Thrombocytopenia is a condition in which there is a lower-than-normal number of platelets in the blood. It may result in easy bruising and excessive bleeding from wounds or bleeding in mucous membranes and other tissues.
Researchers determined the neutralization potency of sera from people vaccinated with BNT162b2, mRNA-1273, or ChAdOx1 against the novel SARS-CoV-2 Omicron variant.
Over 90 percent of patients with transfusion-dependent thalassemia, an inherited blood disorder, no longer needed monthly blood transfusions years after receiving gene therapy, according to an international Phase 3 clinical trial that for the first time included children younger than 12 years of age.
Researchers investigated the role of platelets in the adverse immune response against a COVID-19 vaccine.
Researchers assessed the intensity of association between SARS-CoV-2 infection and risks of various respiratory and non-respiratory complications.
In a recent study posted to the Research Square* preprint server, researchers conducted a systematic review to investigate any association between immunoglobulin A (IgA) vasculitis and coronavirus disease 2019 (COVID-19) in children.
The clinical and imaging characteristics of COVID-19 breakthrough infections in fully vaccinated patients tend to be milder than those of partially vaccinated or unvaccinated patients, according to a new multicenter study published in the journal Radiology.
In a new study, a team of researchers estimated the pre-pandemic incidence rates of adverse events of special interest now observed in association with COVID-19 vaccines in Canada.
In a new study, researchers engineered the bacterial strain, Salmonella, to express differently-sized antigens to serve as vaccine platforms.
One dose of Ad5-nCoV (Convidecia), a COVID-19 vaccine developed in China, is 57.5% effective against symptomatic COVID-19 and 91.7% effective against severe COVID-19 disease beginning 28 days postvaccination, according to a phase 3 randomized controlled trial published in The Lancet.
A collaborative team from the School of Medicine at the University of Cardiff, Wales and a range of US institutions used the UK's national synchrotron, Diamond Light Source, to help reveal the details of how a protein in the blood is attracted to a key component of Adenovirus based vaccines.
Researchers examined autopsy tissue samples of hearts from patients who died early in the COVID-19 pandemic.
A recent study conducted in the United States has revealed that thrombosis with thrombocytopenia syndrome following adenoviral vector-based coronavirus disease 2019 (COVID-19) vaccination is a rare event.
A new preprint explores the efficacy of vaccination against infection with SARS-CoV-2 in pregnancy.
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) produces inflammatory cytokine storms. But an FDA-approved anti-rheumatic drug, Auranofin, used to treat autoimmune and infectious diseases, may also help serve as an antiviral treatment for COVID-19 infection.
Researchers have investigated the differences between 'classic' myocarditis, COVID-19 induced myocarditis, and vaccine-related myocarditis.
A new preprint deals with the characterization of neutrophil phenotypes in an attempt to provide biomarkers that can predict severe disease in patients hospitalized with COVID-19.
A new study reports on the results of phase III clinical trial on the safety and efficacy of the AstraZeneca-Oxford COVID-19 vaccine.
The results of a new patient survey by the British Liver Trust reveal that over half of chronic liver disease patients say they’ve had procedures cancelled or delayed due to the COVID-19 pandemic.
Researchers from the University of Oxford have today announced the results of a study into thrombocytopenia (a condition with low platelet counts) and thromboembolic events (blood clots) following vaccination for Covid-19, some of the same events which have led to restricted use of the Oxford-AstraZeneca vaccine in a number of countries.
Treatment with atezolizumab plus carboplatin and pemetrexed was safe and yielded promising brain progression-free survival in patients with nonsquamous non-small cell lung cancer with untreated and asymptomatic brain metastases.