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Environment rich in sensory stimuli restores memory in mice with neurodegeneration

Mice whose brains had lost a large number of neurons due to neurodegeneration regained long-term memories and the ability to learn after their surroundings were enriched with toys and other sensory stimuli, according to new studies by Howard Hughes Medical Institute researchers.

30 Apr 2007

Roche and Transgene S.A. partner on HPV vaccine program

Roche and Transgene S.A. have announced that they have entered into an exclusive worldwide collaboration agreement to develop and commercialize products from Transgene's therapeutic vaccine program against Human Papilloma Virus-mediated diseases.

11 Apr 2007

Study provides a boost for efforts to reverse type-1 diabetes

Researchers have been able to confirm most but not all of the results of a high-profile study that brought new hope to diabetes patients. This study provides a boost for efforts to reverse type-1 diabetes in recently diagnosed patients but not for efforts to grow new islets from spleens.

27 Mar 2006

Scientists develop a way to block the signals responsible for neuropathic pain

Remember how it felt the last time you burned your finger on a hot stove? Imagine what it's like to have that burning pain in your hands or feet all the time and know there's virtually nothing you can do about it.

1 Jun 2005

Secreted signaling protein called Wnt10b secret to new drugs for preventing or treating osteoporosis

Leaping tall buildings in a single bound may be out of the question, but the genetically engineered "supermice" in Ormond MacDougald's laboratory at the University of Michigan Medical School are definitely stronger than average.

22 Feb 2005

Evolutionarily ancient enzyme-repair system used to identify type of DNA damage responsible for the onset of skin-tumor development

In a finding that broadens our insight into the cause of certain kinds of UV-induced skin cancer, researchers at Erasmus University Medical Center (Rotterdam, The Netherlands) have employed an evolutionarily ancient enzyme-repair system to identify the principal type of DNA damage responsible for the onset of skin-tumor development.

26 Jan 2005

Benitec receives exclusive rights to use DNA technology pioneered at Stanford University for all RNAi therapeutic uses

Benitec has announced an exclusive licensing deal with Stanford University. Under the license, Benitec receives exclusive rights to use the Minicircle DNA technology pioneered at Stanford University for all RNAi therapeutic uses, with sub-licensing rights.

18 Oct 2004

Scientists discover breakthrough method to treat neuronal diseases

What do stroke, epilepsy, head or spinal cord trauma, Parkinson’s disease and Alzheimer’s disease patients have in common? They all suffer from neuronal cell death brought about by the absence or malfunction of specific genes.

30 Aug 2004

U-M scientists say Wnt protein prevents obesity by inhibiting fat cell development

Genetically engineered mice, created at the University of Michigan Medical School, are living every dieter's dream.

29 Jun 2004

New research findings in study of Rett Syndrome

Rudolf Jaenisch of the Whitehead Institute of Biomedical Research in Cambridge, MA reports in the April 6, 2004 online issue of the Proceedings of the National Academy of Sciences that introduction of the MeCP2 protein into post-mitotic nerve cells of MeCP2 mutant mice rescues the symptoms of Rett Syndrome. This raises the possibility that neurons are functionally normal in a newborn child and that neural dysfunction manifests itself only later due to prolonged MeCP2 deficiency. If correct, therapeutic strategies aimed at preventing the onset of Rett symptoms could be initiated at birth.

7 Apr 2004