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Tyco declares quarterly dividend of CHF 0.22 per share

The Board of Directors of Tyco International Ltd. today declared a quarterly dividend of 0.22 Swiss Francs (CHF) per share, payable on August 25, 2010 to shareholders of record at the close of business on July 30, 2010, subject to a required filing with the Swiss Commercial Register.

8 Jul 2010

UTHealth Biotechnology Commercialization Center leases over three-quarters of available space

The University of Texas Health Science Center at Houston (UTHealth) announced that its Biotechnology Commercialization Center (BCC) has leased more than three-quarters of its available space to eight Texas-based startups in less than a year. The center's focus is to assist biotech entrepreneurs and small companies with the translation of discoveries into innovative health solutions.

8 Jul 2010

Alnylam Pharmaceuticals initiates dosing in Phase I human clinical study with ALN-TTR01

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today it has initiated dosing in a Phase I human clinical study with ALN-TTR01. The study is aimed at evaluating the safety and tolerability of ALN-TTR01 in patients with transthyretin -mediated amyloidosis, and is also designed to provide preliminary data on human proof of concept based on measurements of TTR serum levels.

7 Jul 2010

Molecular Templates enters into oncology drug discovery and translation research agreement with ImClone

Molecular Templates announced today that it has entered into a collaborative oncology drug discovery and translation research agreement with ImClone Systems, a wholly-owned subsidiary of Eli Lilly and Company.

7 Jul 2010

SAIC-Frederick, Fluidigm collaborate to decode entire genome of Epstein-Barr virus

SAIC-Frederick, Inc. and Fluidigm Corporation are collaborating to decode the entire genome of the Epstein-Barr virus (EBV) using technology that can speed up research on the genetic basis of cancer and other diseases.

1 Jul 2010

Ronin, Hcf-1 bind together to control gene program that stimulates growth of stem cells

Ronin, crucial to the self-renewal of embryonic stem cells, and a co-regulator called Hcf-1, binds to a small strand of DNA called a hyperconserved enhancer element to control a gene "program" that stimulates growth of the stem cells and may even play a role in cancer, said a group of researchers led by Baylor College of Medicine in a current report in the journal Genes and Development.

1 Jul 2010

MPIB researcher makes methodical progress in the area of genetic code engineering

Proteins are the main actors in our body: They transport substances, convey messages or carry out vital processes in their role as molecular machines. The "helmsmen of the cell" are composed of amino acids, whose sequence is already defined by the heritable information in every living being. The translation of this information during the production of proteins (protein synthesis) is determined by the genetic code.

1 Jul 2010

Alnylam receives Portuguese, Swedish, British approvals to initiate ALN-TTR01 Phase I study in ATTR

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today that its applications for ALN-TTR01 have been given clearance by Portuguese, Swedish, and British regulatory authorities to begin clinical testing. The trial will begin enrolling patients shortly in a blinded, randomized, placebo-controlled, multicenter Phase I study.

29 Jun 2010

Helicos BioSciences to develop, market MDx tests that utilize HeliScope Single Molecule Sequencer

Helicos BioSciences Corporation announced today that it is in the early stages of validating molecular diagnostic (MDx) tests that utilize its HeliScope® Single Molecule Sequencer. The HeliScope Sequencer's ability to sequence single molecules of natural, unamplified DNA or RNA simplifies the diagnostic testing workflow obviating the need for the amplification steps utilized by most genetic analysis methods.

28 Jun 2010

Experts to discuss latest trends in treatments, diagnostic techniques for managing HCC

Today, world renowned experts have assembled in Dubrovnik, Croatia to discuss the latest trends in treatment and cutting edge research in diagnostic techniques that will shape the future management of hepatocellular carcinoma - the third most common cause of cancer-related death globally, and a leading cause of death among patients with liver cirrhosis.

28 Jun 2010

Entelos agree to the terms of non-exclusive perpetual license to Metabolism Physiolab platform for Pfizer

Entelos, Inc. announced today that it has agreed to the terms of a non-exclusive perpetual license to its Metabolism Physiolab platform for Pfizer Inc. The perpetual license will include access for Pfizer to Entelos' PhysioLab Modeler software and its PhysioLab Simulation Server.

24 Jun 2010

Local health clinics in U.S. do not offer diabetes screening, obesity prevention programs to poor clients: Study

A new nationwide study finds that some local health clinics do not offer diabetes screening or obesity prevention programs to their clients, who tend to be poor. The clinics need to be "armed and equipped" to respond to the growing threat from type 2 diabetes and obesity in the United States, said researcher and study co-author Ann Albright. "These are huge problems that we're facing. We want to be sure that we're responding effectively."

23 Jun 2010

Regulus Therapeutics, sanofi-aventis partner to develop and commercialize microRNA therapeutics

Regulus Therapeutics Inc. and sanofi-aventis announced today that they have entered into a global, strategic alliance to discover, develop, and commercialize microRNA therapeutics. The alliance represents the largest microRNA partnership formed to date, valued at potentially over $750 million, and includes a $25 million upfront fee, a $10 million future equity investment subject to mutual agreement on company valuation, and annual research support for three years with the option to extend two additional years.

22 Jun 2010

Electron cryomicroscopy helps observe molecules in hydrated state close to natural state

Gene expression takes place in two stages: the transcription of DNA to RNA by an enzyme called RNA polymerase, , followed by the translation of this RNA into proteins, whose behaviour affects the characteristics of each individual.

21 Jun 2010

Stony Brook team creates live attenuated influenza virus vaccine by computer-aided rational design

A team of molecular biologists and computer scientists at Stony Brook University have used a novel method to weaken (attenuate) influenza virus by way of designing hundreds of mutations to its genetic code to create an effective vaccine. Reported online and in the July issue of Nature Biotechnology, the method may be a major step in developing more effective and safe vaccines against influenza, which claims 250,000 to 500,000 lives annually worldwide, partly because existing vaccines are not fully effective.

17 Jun 2010

QR Pharma, Massachusetts General Hospital announce Parkinson's disease research collaboration

QR Pharma, Inc. (QR) and Massachusetts General Hospital announced today a new collaborative research agreement to work on a treatment for Parkinson's disease (PD).

17 Jun 2010

Researchers study science and clinical treatment of FAS

It's long been known that alcohol use in pregnancy can lead to children with mental retardation and birth defects, but researchers who study fetal alcohol syndrome have not made definitive progress on preventing the disorder, detecting it early, or effectively treating it, say researchers from Georgetown University Medical Center.

16 Jun 2010

Interventions are needed to make people exercise after cardiac event

Researchers from the Frances Payne Bolton School of Nursing at Case Western Reserve University found that one year after 248 individuals completed a 12-week cardiac rehabilitation program following a heart attack, bypass surgery or angioplasty, only 37% exercised three times a week to keep their hearts healthy.

16 Jun 2010

Cartoon moms combat obesity

Two Latina mothers are heroes in the new comic book, Small Changes Big Results from the Frances Payne Bolton School of Nursing at Case Western Reserve University. Their quest is to create a healthier lifestyle for their children and families and combat obesity.

15 Jun 2010

Helix BioPharma third-quarter revenues increase 20.6%

Helix BioPharma Corp. today announced financial results for the third quarter ended April 30, 2010.

11 Jun 2010

Translation News and Research

Tyco declares quarterly dividend of CHF 0.22 per share

UTHealth Biotechnology Commercialization Center leases over three-quarters of available space

Alnylam Pharmaceuticals initiates dosing in Phase I human clinical study with ALN-TTR01

Molecular Templates enters into oncology drug discovery and translation research agreement with ImClone

SAIC-Frederick, Fluidigm collaborate to decode entire genome of Epstein-Barr virus

Ronin, Hcf-1 bind together to control gene program that stimulates growth of stem cells

MPIB researcher makes methodical progress in the area of genetic code engineering

Alnylam receives Portuguese, Swedish, British approvals to initiate ALN-TTR01 Phase I study in ATTR

Helicos BioSciences to develop, market MDx tests that utilize HeliScope Single Molecule Sequencer

Experts to discuss latest trends in treatments, diagnostic techniques for managing HCC

Entelos agree to the terms of non-exclusive perpetual license to Metabolism Physiolab platform for Pfizer

Local health clinics in U.S. do not offer diabetes screening, obesity prevention programs to poor clients: Study

Regulus Therapeutics, sanofi-aventis partner to develop and commercialize microRNA therapeutics

Electron cryomicroscopy helps observe molecules in hydrated state close to natural state

Stony Brook team creates live attenuated influenza virus vaccine by computer-aided rational design

QR Pharma, Massachusetts General Hospital announce Parkinson's disease research collaboration

Researchers study science and clinical treatment of FAS

Interventions are needed to make people exercise after cardiac event

Cartoon moms combat obesity

Helix BioPharma third-quarter revenues increase 20.6%

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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