Translation News and Research

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New high-resolution data on intact ribosome

A new, sharper picture of the nano-machine that translates our genetic program into proteins promises to help researchers explain how some types of antibiotics work and could lead to the design of better ones.

7 Nov 2005

Study provides insight into cellular defenses against genetic mutation

With their latest discovery, researchers have significantly advanced the understanding of how human cells protect themselves from constant and potentially destructive changes in gene expression.

25 Oct 2005

Discovery of a new kind of messenger RNA molecule

Researchers at Cold Spring Harbor Laboratory have discovered a new kind of messenger RNA molecule that is converted from non-protein coding status to protein coding status in response to cellular stress such as viral infection.

20 Oct 2005

dnaJP1 - novel drug for the treatment of rheumatoid arthritis

Researchers at the University of California, San Diego (UCSD) School of Medicine have announced successful completion of Phase II clinical trials of a novel drug for the treatment of rheumatoid arthritis (RA), one that works without suppressing the patient's immune system.

16 Oct 2005

RPL26 and nucleolin play critical roles in controlling the production of p53

Investigators at St. Jude Children's Research Hospital have discovered a previously unrecognized mechanism that controls a key protein linked to the cell's response to stress - a finding that holds promise for new ways to enhance cancer therapies or protect cells from dying after exposure to damaging chemicals or radiation.

9 Oct 2005

Cancer incidence among women has increased slightly

Overall rates of cancer death for both men and women have declined in the United States, and cancer incidence has remained stable among men. However, overall cancer incidence among women has increased slightly, according to a special article that appears in the October 5 issue of the Journal of the National Cancer Institute.

4 Oct 2005

Lack of oxygen in body tissues creates a defect of red blood cells that further exacerbates the condition by constricting blood vessels in the lung

What's more, the team demonstrated through studies in people and animals that inhalation of a 'souped up' form of nitric oxide, which targets red blood cells, reverses the blood abnormality to restore normal lung pressure.

3 Oct 2005

Translation elongation factor eEF1A2 is is a potential oncogene that is overexpressed in two-thirds of breast tumors

The tissue-specific elongation factor eEF1A2 might be an oncoprotein involved in breast cancer.

12 Sep 2005

MRC call for proposals in experimental medicine

The Medical Research Council (MRC) has launched a Call for Proposals in experimental medicine today as part of its £15 million commitment to promote the translation of laboratory research into clinical practice for the benefit of patients.

7 Sep 2005

New understanding of how our genome works to produce a complex organism like a human being

A series of discoveries by an international consortium of scientists, including a team from The University of Queensland's Institute for Molecular Bioscience (IMB), will transform our understanding of how our genome works to produce a complex organism like a human being.

4 Sep 2005

Opiate drugs such as morphine leave animals more vulnerable to stress

A new study has found that opiate drugs such as morphine leave animals more vulnerable to stress. This means that stress and opiates are in a vicious cycle: Not only does stress trigger drug use, but in return the drug leaves animals more vulnerable to stress.

30 Aug 2005

Genetic makeup may detemine likely success of quit smoking therapies

A study by researchers at the Transdisciplinary Tobacco Use Research Center (TTURC) of the University of Pennsylvania School of Medicine indicates that a smoker's genetic make-up may affect whether they quit or not while using either bupropion (Zyban) or nicotine replacement therapies (NRTs) such as the nicotine patch or nasal spray.

30 Aug 2005

Strategic analyses of European In-Vitro cancer diagnostics market - Cancer research yields promising results

Every year, nearly one in four Europeans - a total of almost one million people - dies from cancer, giving Europe the dubious distinction of having amongst the highest cancer-related mortality rates in the world. Even as cancer remains a difficult disease to diagnose, often resulting in either poor diagnosis or misdiagnosis, the number of new cancer cases is set to double by 2020.

2 Aug 2005

Primordial soup where life began on earth was hot and not cold

A new theory that explains why the language of our genes is more complex than it needs to be also suggests that the primordial soup where life began on earth was hot and not cold, as many scientists believe.

2 Aug 2005

High rates of cervical cancer are indicators of larger problems in access to health care

The report also finds that cervical cancer mortality, which is higher in certain geographic areas and populations, is a marker for other health disparities.

21 Jul 2005

Chronic Obstructive Pulmonary Disease (COPD) rates in women skyrocket

The death rate for one of the most lethal diseases in North America has skyrocketed for women in the last 20 years, and a team of researchers from the University of British Columbia and the B.C. Centre of Excellence for Women's Health wants to find out why.

19 Jul 2005

Study challenges understanding of how messenger RNAs are translated into proteins

Our understanding of how messenger RNAs are translated into proteins is challenged by a new study published in the Open Access journal Journal of Biology.

27 Jun 2005

Researchers use PET/CT for molecular imaging of the heart

For the first time, researchers used positron emission tomography (PET)/computed tomography (CT) for imaging the subcellar function of the heart - from its subcellular function to its morphologic appearance. The results of the study were reported at the Society of Nuclear Medicine's 52nd Annual Meeting June 18–22 in Toronto.

20 Jun 2005

Fewer diabetics end up in hospital

According to new research from the U.S. Centers for Disease Control and Prevention (CDC), Americans with diabetes are less likely than they were a decade ago, to need hospitalization for serious complications such as kidney failure.

14 Jun 2005

Canadian Diabetes Association, UBC partner on funding for childhood diabetes research

A new partnership announced by the Canadian Diabetes Association and the University of British Columbia (UBC) will help fund research in childhood diabetes. Not only will this research further investigate type 1 diabetes, it will also explore the areas of type 2 diabetes and obesity in children, a problem of growing concern and proportions.

23 Apr 2005