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Study compares strategies for BK virus nephropathy

For kidney transplant recipients with a serious complication called BK virus-associated nephropathy (BKVAN), promptly cutting back on anti-rejection drugs reduces the risk of losing the kidney (graft loss), according to a report in the November Clinical Journal of the American Society of Nephrology (CJASN).

26 Nov 2008

Study evaluates corneal collagen cross-linking in subjects with progressive keratoconus

Presently keratoconus is treated through eyeglasses, hard contact lenses, and a newer treatment, INTACS plastic rings inserted into the mid layer of the cornea to flatten it, changing the shape and location of the cone.

26 Nov 2008

Understanding donor-recipient genetics could decrease early kidney transplant complications

Researchers at the University of Pennsylvania School of Medicine have found an association between the genetics of donor-recipient matches in kidney transplants and complications during the first week after transplantation.

25 Nov 2008

Scientists create synthetic Heparin in more varieties

Scientists at the University of North Carolina at Chapel Hill have learned to customize a key human enzyme responsible for producing heparin, opening the door to a more effective synthetic anticoagulant as well as treatments for other conditions.

25 Nov 2008

Follow up results from first case of pulmonary hypertension treated with stem cells

Dr. Leonel Fernandez Liriano, Professor of Medicine at Pontifical Catholic University School of Medicine (PCUSM), announced nine month follow up results for the first patient treated with engineered stem cells in a clinical study of primary pulmonary hypertension.

25 Nov 2008

Improvement seen regarding racial disparities for liver transplantation, disparities for women remain

Following introduction of a new system in 2002 to determine the allocation of donated livers, black patients no longer are less likely to receive a liver transplant, but disparities for women remain, according to a study in the November 26 issue of JAMA, the Journal of the American Medical Association.

25 Nov 2008

Study looks at ventricular assist device outcomes

Ventricular assist devices, or VADs - surgically-placed mechanical pumps that can support failing hearts or buy time to transplant - are associated with high hospital costs and high rates of early death among Medicare recipients, say researchers at Duke University Medical Center.

25 Nov 2008

Researchers repair injured heart muscle with novel stem cells

Researchers at Children's Hospital of Pittsburgh of UPMC have been able to effectively repair damaged heart muscle in an animal model using a novel population of stem cells they discovered that is derived from human skeletal muscle tissue.

25 Nov 2008

Researchers develop new strategy for broad spectrum anti-viral drugs

Bavituximab, an anti-viral drug developed by UT Southwestern Medical Center researchers, shows promise as a new strategy to fight viral diseases, including potential bioterrorism agents.

24 Nov 2008

Pancreatic duct cells identified as new source of insulin-producing cells

Researchers at the Joslin Diabetes Center have shown that insulin-producing pancreatic beta cells can form after birth or after injury from progenitor cells within the pancreas that were not beta cells, a finding that contradicts a widely-cited earlier study that had concluded this is not possible.

24 Nov 2008

New hope for lung disease pulmonary alveolar proteinosis

A tale of two sisters has helped researchers solve a medical mystery and discover a familial genetic mutation that causes an inherited form of the lung disease Pulmonary Alveolar Proteinosis (PAP).

24 Nov 2008

Humoral immunity in kidney transplantation

There are more than 76,000 end-stage renal disease patients waiting for one of the 17,000 kidneys transplanted each year, making a host rejection an unacceptable waste.

24 Nov 2008

Scientists develop unlimited pure insulin-producing cells from mouse embryonic stem cells

These pure insulin-producing cells, which according to electron microscopy studies, have the same sub-cellular structures as the insulin-producing cells naturally found in the pancreas, were highly effective in treating diabetes in the mouse model.

20 Nov 2008

Scientists trick immune system of mice into believing transplanted islets are its own cells

The body's immune system hates strangers. When its security patrol spots a foreign cell, it annihilates it.

20 Nov 2008

First trachea transplant and first tissue transplant without immunosuppression

After 4 years of going from consultation to consultation, Claudia Castillo finally found a solution to her respiratory problems.

19 Nov 2008

Pros and cons of gastric bypass surgery

Severely obese patients who underwent two different gastric bypass techniques had lost up to 31 per cent of their Body Mass Index (BMI) after four years, with no deaths reported among the 50 study subjects, according to the November issue of the British Journal of Surgery.

18 Nov 2008

First tissue-engineered windpipe transplant

The first tissue-engineered trachea (windpipe), utilising the patient's own stem cells, has been successfully transplanted into a young woman with a failing airway.

18 Nov 2008

Scientists use patient's own stem cells to treat heart failure

Researchers at the University of Utah are enrolling people in a new clinical trial that uses a patient's own stem cells to treat ischemic and non-ischemic heart failure.

17 Nov 2008

Ethnic disparities in treatment of trauma patients

The initial evaluation and management of injured patients from minority ethnic groups nationwide appears to be similar to that of non-Hispanic white patients, according to a report in the November issue of Archives of Surgery.

17 Nov 2008

A new method to control bleeding in hemophilia

Investigators at Children's Research Institute, BloodCenter of Wisconsin's Blood Research Institute and the Medical College of Wisconsin have discovered a new way to help the blood clot by having the missing clotting factor packaged in the patient's own platelets.

13 Nov 2008