Transplant News and Research

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Cancer requires support from immune system to develop, researchers report

Tumors that grow around nerves in a rare genetic disease need cooperation from cells from the immune system in order to grow, reports a team of scientists, including researchers from UT Southwestern Medical Center.

30 Oct 2008

Worries over test for mad cow disease

A new test to screen blood for the incurable human form of mad cow disease could be available within 18 months, but it has raised concerns.

21 Oct 2008

New Zealand to trial pig cells as treatment for type 1 diabetes

Authorities in New Zealand have given conditional approval for a human trial to go ahead using pig cells to treat type 1 diabetes.

21 Oct 2008

Targeted cell delivery to the cervical spinal cord is a promising strategy to slow loss of motor neurons in ALS

In a disease like ALS - one that's always fatal and that has a long history of research-resistant biology - finding a proof of principle in animal models is significant.

20 Oct 2008

5 things you should know about stem cell research

In just a few weeks, Michigan voters will have an important decision to make when casting their ballots.

13 Oct 2008

New rapid test for rare leukemia

A new twist on a well-known cell sorting technique may allow physicians to diagnose rare leukemias in hours instead of weeks, according to a study by researchers at the Stanford University School of Medicine and UC-San Francisco.

6 Oct 2008

Researchers explore issues related to multiple myeloma treatment

Multiple myeloma (MM) is a cancer of plasma cells that affects approximately 3 in 100,000 people each year. Although there is no cure for this disease, researchers have developed treatments that help relieve pain, control complications, and slow the progress of MM in many patients. Unfortunately, some of the most effective therapies also have toxic side effects that can pose serious health risks and reduce quality of life. In the October issue of Mayo Clinic Proceedings, two articles authored by Mayo researchers address the issue of how to balance the risks and benefits associated with MM treatments.

6 Oct 2008

Discovery of promising new chemotherapy target for a deadly form of leukemia

Cancer researchers at the Stanford University School of Medicine have discovered a promising new chemotherapy target for a deadly form of leukemia. Their discovery hinges on a novel "double agent" role for a molecular signal that regulates cell growth.

17 Sep 2008

Scientists identify kidney failure susceptibility gene

Scientists at Johns Hopkins schools of Public Health and Medicine have, for the first time, identified variants in the gene MYH9 that are associated with increased risk for non-diabetic end stage renal disease (ESRD,) which is the near-loss of kidney function leading to either dialysis of transplant. MYH9, located on the 22 chromosome, is the first gene identified for common forms of kidney disease.

15 Sep 2008

Depressed dialysis patients more likely to be hospitalized or die, researcher finds

Dialysis patients diagnosed with depression are nearly twice as likely to be hospitalized or die within a year than those who are not depressed, a UT Southwestern Medical Center researcher has found.

14 Sep 2008

Bariatric surgery cost-effective for treating obesity

Health insurers can offset the cost of laparoscopic or traditional bariatric surgery as a weight-loss treatment for obese patients within two to four years as a result of savings on other medical costs, according to a study published this month in the American Journal of Managed Care, the Wall Street Journal reports.

9 Sep 2008

Health care professionals seeing more children with fatty liver disease; condition prevalent among Hispanics

As many as 2% to 5% of children older than age five -- most of whom are obese -- are thought to have nonalcoholic fatty liver disease, and the condition seems to be most prevalent among Hispanic children, the AP/San Mateo Daily Journal reports.

4 Sep 2008

FDA authorizes INDA for recombinant human C1 inhibitor in kidney transplantation

Biotech company Pharming Group NV has announced that the US Food and Drug Administration (FDA) has authorized a clinical study with recombinant human C1 inhibitor (rhC1INH) for the treatment of antibody-mediated rejection (AMR) in kidney transplantation. Dr. Hans Sollinger of the University of Wisconsin, Madison will conduct the clinical trial with rhC1INH under an Investigator IND from the FDA.

3 Sep 2008

Study points to one cause of higher rates of transplanted kidney rejection in blacks

A Johns Hopkins research team reports it may have an explanation for at least some of the higher organ rejection rates seen among black - as compared to white - kidney transplant recipients.

31 Aug 2008

Why transplanted insulin cells die

New research can enhance survival of islets transplants and improve treatment of type 1 diabetes. Transplantation of insulin-producing cell islets, so-called islets of langerhans is an appealing strategy for treatment of type 1 diabetes. But it turns out that these are short-lived, and the procedure needs to be repeated.

28 Aug 2008