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New drug candidate found to be highly effective in treating rare sight-threatening eye infection

A drug candidate, based on pioneering UCL and Moorfields Eye Hospital research and currently under development by SIFI S.p.A., has been found to be highly effective in treating a rare sight-threatening eye infection in a new international clinical trial.

26 Oct 2023

Brain injury expert calls for reforms to legal definition of death in the United States

After surveying the views expressed by 41 advocacy, medical, and transplant-focused organizations on the Uniform Determination of Death Act, a brain injury expert is calling for much-needed reforms to the legal definition of death in the United States.

26 Oct 2023

Viral rebound common in lung transplant recipients treated with nirmatrelvir/ritonavir for COVID-19

Data on the viral rebound and safety of nirmatrelvir/ritonavir in lung transplant (LTx) recipients are limited.

24 Oct 2023

Potato starch supplement may help prevent gvhd in bone marrow transplant patients

Researchers at Baylor College of Medicine and the University of Michigan conducted a phase I pilot study to assess the feasibility of using potato starch as a dietary intervention to modify the gut microbiome in bone marrow transplant patients.

19 Oct 2023

Microscale device for eye implantation may be used in the treatment of diabetes

Researchers in Sweden have developed a microscale device for implantation in the eye, which presents new opportunities for cell-based treatment of diabetes and other diseases.

18 Oct 2023

Gut microbiota linked to Alzheimer's disease

Researchers have discovered the link between the gut microbiota and Alzheimer's disease.

17 Oct 2023

Live vaccinations found to be safe for pediatric organ transplant recipients

Live vaccinations provided to children who previously received liver or kidney transplants were found to be safe and prompted an immune response to guard against several life-threatening conditions, according to a new study published Oct. 12, 2023, in JAMA Network Open.

16 Oct 2023

Researchers identify genes that may improve success of fecal microbe transplants

Fecal microbe transplants from healthy donors can treat patients with recurrent Clostridium difficile infections. However, after tens of thousands transplants, little was known about which donor strains provide long-term engraftment, and which engraft early after the transplant.

13 Oct 2023

Pitt scientists develop new approach to reduce side effects of organ transplants

Giving living donor liver transplant recipients an infusion of immune cells derived from their donor a week before transplantation is feasible, safe – and may lead to recipients being successfully weaned off immunosuppressant medications without rejecting the transplanted organ.

11 Oct 2023

Non-melanoma skin cancer causing greater number of global deaths than melanoma, study finds

Non-melanoma skin cancer (NMSC) is causing a greater number of global deaths than melanoma, the more serious form of skin cancer, a new study presented today at the European Academy of Dermatology and Venerology (EADV) Congress 2023 has found.

10 Oct 2023

Gut health and leukemia: Exploring the crucial connection between diet and microbiota changes

Gut microbiota's role in leukemia treatment responses is explored, with evidence suggesting diet and prebiotics may help manage microbiota alterations in patients. Diet during pregnancy, breastfeeding, and gut microbiota composition all intersect, potentially influencing leukemia risks and treatment outcomes.

8 Oct 2023

Can viruses in our gut be a game changer for health?

Bryan Hsu, funded by a $1.9 million award, aims to explore the role of lytic bacteriophages in mammalian guts, specifically focusing on their interaction with gut bacteria. Through innovative models, the study seeks to elucidate whether phages, known to infect bacteria, could significantly impact gut health or be leveraged to combat antibiotic-resistant bacterial infections.

3 Oct 2023

New model prioritizes lung transplant candidates based on time on waitlist

A team from Cleveland Clinic has developed a new model for prioritizing patients waiting for a lung transplant, aimed at improving outcomes and reducing deaths among those in need of donor lungs.

29 Sep 2023

New recommendations to improve outcomes at US congenital heart surgery centers

A set of recommendations to address the known variation in outcomes at US congenital heart surgery centers has been endorsed by 15 collaborating societies led by the Congenital Heart Surgeons' Society (CHSS).

29 Sep 2023

Researchers describe the origin and fate of liver myofibroblasts

Hepatic fibrosis occurs when scar tissue replaces damaged cells in the liver. Over time, accumulating scarring distorts the liver, interferes with its blood supply and may progressively lead to worsening consequences, from cirrhosis to liver failure to liver cancer.

28 Sep 2023

Commonly used anti-viral drugs reduce risk of hospitalization, death in patients with mild COVID-19

New Cleveland Clinic-led research shows commonly used COVID-19 anti-viral drugs Paxlovid (nirmatrelvir) and Lagevrio (molnupiravir) reduce risk of hospitalization and death in high-risk patients with mild disease, even with Omicron subvariants.

28 Sep 2023

Acute kidney injury patients on dialysis may be overtreated

Patients with acute kidney injury requiring outpatient dialysis after hospital discharge receive the same care as those with the more common end-stage kidney disease, according to a study led by UC San Francisco.

28 Sep 2023

Living donor liver transplantation improves waitlist outcomes in high-risk cirrhosis patients

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 17, entitled, "Availability of living donor optimizes timing of liver transplant in high-risk waitlisted cirrhosis patients."

26 Sep 2023

UMMC transplant team performs second pig heart transplant on patient with end-stage heart disease

After world's first successful transplant in 2022, also performed at the University of Maryland Medical Center (UMMC), this groundbreaking transplant team performed second pig heart transplant on patient deemed ineligible for traditional heart transplant.

25 Sep 2023

Cellular crosstalk between mother and offspring is more complex than expected

Scientists have known for decades that pregnancy requires a mother's body to adjust so that her immune system does not attack the growing fetus as if it were a hostile foreign invader.

22 Sep 2023

Transplant News and Research

New drug candidate found to be highly effective in treating rare sight-threatening eye infection

Brain injury expert calls for reforms to legal definition of death in the United States

Viral rebound common in lung transplant recipients treated with nirmatrelvir/ritonavir for COVID-19

Potato starch supplement may help prevent gvhd in bone marrow transplant patients

Microscale device for eye implantation may be used in the treatment of diabetes

Gut microbiota linked to Alzheimer's disease

Live vaccinations found to be safe for pediatric organ transplant recipients

Researchers identify genes that may improve success of fecal microbe transplants

Pitt scientists develop new approach to reduce side effects of organ transplants

Non-melanoma skin cancer causing greater number of global deaths than melanoma, study finds

Gut health and leukemia: Exploring the crucial connection between diet and microbiota changes

Can viruses in our gut be a game changer for health?

New model prioritizes lung transplant candidates based on time on waitlist

New recommendations to improve outcomes at US congenital heart surgery centers

Researchers describe the origin and fate of liver myofibroblasts

Commonly used anti-viral drugs reduce risk of hospitalization, death in patients with mild COVID-19

Acute kidney injury patients on dialysis may be overtreated

Living donor liver transplantation improves waitlist outcomes in high-risk cirrhosis patients

UMMC transplant team performs second pig heart transplant on patient with end-stage heart disease

Cellular crosstalk between mother and offspring is more complex than expected

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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