Troponin News and Research

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Elevated troponin I should not rule out donor hearts

Donor cardiac troponin I level is not associated with intermediate-term mortality, cardiac allograft vasculopathy or primary graft failure in patients receiving heart transplants, US researchers report.

28 Jun 2016

Protein-based CHD risk score developed

Researchers have screened over 1000 plasma proteins to develop a predictive score in patients with stable coronary heart disease.

22 Jun 2016

Temporal hs-cTNT changes may predict future heart disease

Temporal increases in high-sensitivity cardiac troponin T are associated with a significantly increased risk of coronary heart disease, heart failure and death among people initially free from cardiovascular disease, US study data show.

9 Jun 2016

Rapid NSTEMI exclusion becoming reality

Two studies show that modern high-sensitivity troponin I assays can help physicians to rapidly identify patients with a very low likelihood of having non-ST-segment elevation myocardial infarction.

4 Jun 2016

Rapid hand-held troponin blood test for heart attack diagnosis launched by Philips

Chest pain patients presenting at the emergency department are set to benefit from a major development by Royal Philips. The company today announced that it has CE marked its cardiac troponin I (cTnI) blood test on the Minicare I-20 handheld device. Minicare cTnI delivers its lab comparable test results in less than 10 minutes near the patient, reducing the time for the physician to decide on treatment.

From Philips Healthcare 25 May 2016

Study shows short-term statin treatment does not benefit heart surgery patients

Giving daily doses of statins for a few days before and after heart surgery does not prevent heart muscle damage or the development of atrial fibrillation (AF), according to an international clinical trial led by the University of Oxford and funded by the British Heart Foundation.

5 May 2016

Diagnosing heart attacks in 1 hour: an interview with Dr Richard Body

Cardiac troponin is a highly sensitive and specific biomarker for myocardial injury but concentrations in the blood rise over several hours after the onset of an acute myocardial infarction.

28 Apr 2016

Heart disease patients who experience mental stress ischemia tend to have higher levels of troponin

Some people with heart disease experience a restriction of blood flow to the heart in response to psychological stress. Usually silent (not painful), the temporary restriction in blood flow, called ischemia, is an indicator of greater mortality risk.

4 Apr 2016

PAH role proposed for left heart failure biomarker

Levels of galectin-3 are elevated in patients with pulmonary arterial hypertension and correlate with disease severity, research shows.

10 Mar 2016

Ohio State researchers develop new approach to enhance heart function, cardiovascular performance

For the first time, scientists at The Ohio State University have engineered new calcium receptors for the heart to tune the strength of the heartbeat in an animal model. The research is published online by the journal Nature Communications.

24 Feb 2016

Troponin T test provides possible one hour diagnosis of heart attack

Results from the TRAPID-AMI clinical study have been published online by the Annals of Emergency Medicine, confirming a novel approach for a more rapid diagnosis of heart attack in patients with acute chest pain.

From Roche Sequencing and Life Science 15 Jan 2016

Mast Therapeutics begins vepoloxamer Phase 2 study in patients with chronic heart failure

Mast Therapeutics, Inc., a clinical-stage biopharmaceutical company leveraging its molecular adhesion and sealant technology (MAST) platform to develop novel therapies for sickle cell disease, heart failure, and stroke, announced that it has initiated its Phase 2 study of vepoloxamer for the treatment of patients with chronic heart failure.

26 Oct 2015

Study identifies specific protein that can be early indicator of end-stage renal disease

Mayo Clinic researchers in Rochester, Minnesota, collaborated with the University of Mississippi Medical Center on a recent study, "Troponin T as a Predictor of End-Stage Renal Disease and All-Cause Death in African-American and Whites From Hypertensive Families." For the first time, this study identified the presence of a specific protein in the blood used to look for heart damage.

20 Oct 2015

Sleep apnea associated with evidence of early heart injury in women

Risk factors for obstructive sleep apnea (OSA) and the development of subsequent cardiovascular (CV) complications differ by sex, but it is not clear from prior research whether the effects of sleep apnea on heart disease is similar for men and women.

13 Oct 2015

New test for heart attack may save NHS millions

A simple blood test could be used to rule out the possibility of heart attack in two-thirds of people who attend A&E with chest pains, report UK researchers.

9 Oct 2015

Acute Cardiovascular Care 2015 to be held in Vienna from 17 to 19 October

Acute Cardiovascular Care 2015 will highlight innovations and controversies in the field, guaranteeing great stories on topics relevant to the press.

18 Sep 2015

Patients with suggestive AMI can be triaged more quickly and safely using rapid, sensitive assay

Patients arriving at the emergency department with chest pain suggestive of acute myocardial infarction (AMI) can be triaged more quickly and more safely using a new rapid assay with refined cut-offs, German research suggests.

31 Aug 2015

Radial approach superior than femoral one for coronary angiography and PCI for ACS patients

For the first time, ESC Guidelines published today give the highest degree of recommendation for the radial approach over the femoral one for coronary angiography and percutaneous coronary intervention (PCI) in patients with acute coronary syndromes (ACS).

29 Aug 2015

Commonly used heart attack blood test may identify people at risk for hypertension

Analysis of blood samples from more than 5,000 people suggests that a more sensitive version of a blood test long used to verify heart muscle damage from heart attacks could also identify people on their way to developing hypertension well before the so-called silent killer shows up on a blood pressure machine.

27 Aug 2015

Common marker can help identify patients at high risk for deadly cardiac events

A marker commonly used to determine if a patient is having a heart attack can also be used to identify stable patients at high risk for deadly cardiac events, according to a new study led by investigators at Brigham and Women's Hospital.

13 Aug 2015