Troponin News and Research

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High levels of two proteins in the bloodstream indicate need for action to avoid heart attack

Researchers working to decode chemical SOS signals sent out by disease-damaged hearts believe they now know better when to aggressively clear clogged arteries and when medical procedures may be unnecessary and even harmful.

12 Sep 2006

Redefining myocardial infarction for the 21st century

World Congress of Cardiology Report - Progress in the identification and quantification of biochemical markers of myocardial injury have led to a redefinition of myocardial infarction (MI).

5 Sep 2006

Researchers find viable new sources for stem cell transplants to the heart

Stem cell transplantation is among one of the most exciting and hotly debated areas of medical research today. While the promise of personalized medicine and effective treatments for debilitating diseases drive progress in this area, moral and ethical dilemmas about embryonic cells continues to cloud the field.

14 Mar 2006

Clopidogrel reduces risk of adverse events for patients with acute coronary syndromes undergoing balloon angioplasty

Patients with acute coronary syndromes who were pre-treated with the anti-platelet agent clopidogrel before undergoing a procedure such as balloon angioplasty or stent placement had a reduced risk of adverse events if they received the anti-clotting drug abciximab

14 Mar 2006

Histidine may be key to new therapies for cardiovascular disease

It's just one little amino acid, but it makes all the difference in protecting the heart from the harmful effects of heart attack and cardiac failure. Researchers from the University of Michigan Medical School suggest this amino acid, called histidine, could be the key to a new therapy for cardiovascular disease

23 Jan 2006

Emergency physicians' fear of malpractice in evaluating patients with possible acute cardiac ischemia

A new survey of emergency physicians finds those most concerned about lawsuits are more likely to admit patients with cardiac symptoms and to order more tests. The results will be published by Annals of Emergency Medicine as an early online release July 13 (Emergency Physicians' Fear of Malpractice In Evaluating Patients With Possible Acute Cardiac Ischemia).

13 Jul 2005

Heart attacks in women not being picked up

Women are still less likely than men to be correctly identified as having had a heart attack, despite the publication of new guidance designed to lower the index of suspicion, reveals research in Heart.

16 Jan 2005

Protein in cardiac muscle cells may play a crucial role in heart failure prevention

Scientists at the University of North Carolina at Chapel Hill School of Medicine have shown that a protein in cardiac muscle cells may play a crucial role in heart failure prevention.

5 Jan 2005

Troponin genes offer new insights to familial heart failure

Mutations in the troponin protein complex may be useful for predicting the course of heart failure due to dilated cardiomyopathy and also for guiding treatment and research, according to a new study in the Nov. 16, 2004 issue of the Journal of the American College of Cardiology.

16 Nov 2004

No benefit from early PCI/CABG in high risk unstable angina patients

Patients with chest pain are recognized as being at high risk of subsequent adverse cardiac events when their plasma levels of cardiac troponin are elevated as evidence of myocardial damage.

29 Aug 2004

Dexrazoxane reduces heart damage caused by childhood leukemia treatment with doxorubicin (Adriamycin)

A potent chemotherapy that is highly effective in treating the most common form of childhood leukemia can significantly harm the heart, but findings from a multi-center study

9 Jul 2004

New series of clinical standards to diagnose heart attacks

Diagnosing heart attacks will become a more precise science thanks to the first of a new series of clinical standards just issued by the National Institute of Standards and Technology (NIST). Standard Reference Material (SRM) 2921 (human cardiac troponin complex) will help manufacturers develop and calibrate assays that measure specific protein concentrations in patient blood samples to determine whether a heart attack has occurred.

24 May 2004

High levels of troponin I (TNI) protein in the blood helps identify possible heart damage after cancer treatment

TNI is a protein present exclusively in heart cells. The TNI blood concentration is a well-established marker of heart muscle injury that’s widely used to diagnose and treat heart attacks and other acute coronary syndromes.

18 May 2004