Tumor News and Research

RSS

Yeast-based vaccine induces immune responses and reduces tumor size in mice

Scientists have found that vaccination with a heat-killed, non-toxic yeast that is genetically engineered to manufacture a common tumor protein can induce specific and repeated anti-tumor immune responses in mice.

1 Jul 2008

Cancer cells revert to normal at specific signal threshold

Cancer starts when key cellular signals run amok, driving uncontrolled cell growth. But scientists at the Stanford University School of Medicine report that lowering levels of one cancer signal under a specific threshold reverses this process in mice, returning tumor cells to their normal, healthy state. The finding could help target cancer chemotherapy to tumors while minimizing side effects for the body's healthy cells.

1 Jul 2008

Children's Brain Tumor Foundation's tissue bank consortium may solve dire problem in pediatric cancer research

In a major effort to speed treatment and cures for pediatric brain tumors and cancer, the Children's Brain Tumor Foundation (CBTF) today launched the initial phase of a tissue bank consortium designed to jump-start meaningful analyses that could lead to treatment and cures for these types of cancer, where survival rates are unacceptably low and neurocognitive and other damage is posed by today's treatment options.

1 Jul 2008

Cancer cure in mice to be tested in humans

Scientists at Wake Forest University Baptist Medical Center are about to embark on a human trial to test whether a new cancer treatment will be as effective at eradicating cancer in humans as it has proven to be in mice.

30 Jun 2008

Growth-stimulating molecule called p110beta a promising cancer drug target in prostate tumors

Scientists at Dana-Farber Cancer Institute report they have blocked the development of prostate tumors in cancer-prone mice by knocking out a molecular unit they describe as a "powerhouse" that drives runaway cell growth.

27 Jun 2008

Clinical Data secures European patent for key multi-drug resistance gene

Clinical Data, Inc. has announced that the European Patent Office has granted Patent No. 1232260 to Bernried, Germany-based Epidauros Biotechnologie AG, a wholly-owned subsidiary of Clinical Data, relating to the use of a genetic variant, or biomarker, of the gene MDR1 (also known as ABCB1), which encodes P-glycoprotein (PGP).

26 Jun 2008

A safe and efficient gene delivery method that doesn't involve viruses

The potential of gene therapy has long been hampered by the risks associated with using viruses as vectors to deliver healthy genes, but a new University of Georgia study helps bring scientists closer to a safe and efficient gene delivery method that doesn't involve viruses.

26 Jun 2008

Pregnancy may protect against bladder cancer

Female mice that had never become pregnant had approximately 15 times as much cancer in their bladders as their counterparts that had become pregnant, according to new findings by investigators at the University of Rochester Medical Center. Their work appears online as a rapid communication in the journal Urology.

26 Jun 2008

Jefferson scientists discover way to immunize mice against metastatic disease

Taking advantage of the fact that the intestines have a separate immune system from the rest of the body, scientists at the Kimmel Cancer Center at Jefferson in Philadelphia have found a way to immunize mice against the development of metastatic disease.

24 Jun 2008

Blue curing light for tumors

A blue curing light used to harden dental fillings also may stunt tumor growth, Medical College of Georgia researchers say.

24 Jun 2008

More government in health care is not a prescription for reform

The Center for Medicine in the Public Interest (CMPI) today launched BigGovHealth.org, a new initiative to expose the consequences of greater government control in health care.

24 Jun 2008

The impact of socioeconomic status on survival after cancer in the United States

Cancer patients with low socioeconomic status (SES) have more advanced cancers at diagnosis, receive less aggressive treatment, and have a higher risk of dying in the five years following cancer diagnosis, according to a new study.

23 Jun 2008

Hedgehog signaling is critical for maintenance of the adult coronary vasculature

A set of promising new anticancer agents could have unforeseen risks in individuals with heart disease, suggests research at Washington University School of Medicine in St. Louis.

23 Jun 2008

Less invasive approach for the treatment of cervical intraepithelial neoplasia

In the United States alone, approximately three-and-a-half million women have abnormal Pap smear tests each year.

23 Jun 2008

Discovery of possible new way to block inflammation in autoimmune disease

Researchers from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), a part of the National Institutes of Health (NIH), have identified a promising new target for autoimmune disease treatment - a cell-surface receptor called DR3.

23 Jun 2008

Patient's own infection-fighting T cells put late-stage melanoma into long-term remission

Researchers describe the first successful use of a human patient's cloned infection-fighting T cells as the sole therapy to put an advanced solid-tumor cancer into long-term remission. A team led by Cassian Yee, M.D., an associate member of the Clinical Research Division at Fred Hutchinson Cancer Research Center, reports these findings in the June 19 issue of the New England Journal of Medicine.

19 Jun 2008

New hope for patients with breast cancers resistant to tamoxifen

Researchers have found a new family of therapeutic agents that interferes with the ability of estrogen to stimulate the growth of breast cancer cells. The results of the new study will be presented by Nicole Patterson at The Endocrine Society's 90th Annual Meeting in San Francisco.

16 Jun 2008

Noninvasive molecular imaging technology helps track stem cells in tumors

Using noninvasive molecular imaging technology, a method has been developed to track the location and activity of mesenchymal stem cells (MSCs) in the tumors of living organisms, according to researchers at the Society of Nuclear Medicine's 55th Annual Meeting. This ability could lead to major advances in the use of stem cell therapies to treat cancer.

16 Jun 2008

Novel agents found to inhibit growth of estrogen-dependent breast cancer cells

Researchers have discovered a new family of agents that inhibit the growth of estrogen-dependent breast cancer cells. The finding, described at a meeting of the Endocrine Society, has opened an avenue of research into new drugs to combat estrogen-dependent breast cancers.

16 Jun 2008

Nanoparticles trigger built-in cell-death signal to overcome drug resistance

One of the most vexing problems in treating cancer is the propensity of tumors to develop resistance to a wide range of anticancer drugs. Over 70 percent of ovarian cancer patients, for example, have drug-resistant tumors at the time of their initial diagnosis, and virtually all patients who relapse have drug-resistant tumors.

15 Jun 2008