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Biodegradable drug containing nano-particles effective in killing human breast tumors

Research studies, based at the University of Pennsylvania, demonstrate that biodegradable nano-particles containing two potent cancer-fighting drugs are effective in killing human breast tumors.

11 Apr 2006

Lack of response to herceptin may be reversed with PI3K inhibiting agents

Breast cancer patients with HER2-positive tumors who don't respond to Herceptin (trastuzumab) may benefit from cocktail therapy that includes Herceptin along with one or more PI3K inhibiting agents, say researchers at the University of Texas M. D. Anderson Cancer Center.

11 Apr 2006

Assessment of health-related quality of life in children with cancer: consistency and agreement between parent and child reports

Researchers and physicians can confidently assess quality of life factors in pediatric patients from either the child or parents, according to a new study.

10 Apr 2006

Risk of invasive breast carcinoma among women diagnosed with ductal carcinoma in situ and lobular carcinoma in situ

A new study of women with early stage, localized breast cancer identifies new patterns and risk factors for invasive disease that may influence how patients are treated.

10 Apr 2006

Discovery of new human retrovirus

Howard Hughes Medical Institute researchers and their colleagues have discovered a new retrovirus in humans that is closely related to a cancer-causing virus found in mice. Their findings describe the first documented cases of human infection with a retrovirus that is native to rodents.

10 Apr 2006

Proteins could help predict whether moles will progress into melanoma

For the first time, researchers studying patients with abnormal moles have identified proteins that could help predict whether such moles will progress into melanoma, the deadliest form of skin cancer.

7 Apr 2006

Newly discovered testosterone effect may act on prostate cancer

A newly-discovered mode of action of testosterone is showing great promise in the fight against prostate cancer, with tests showing a 60% reduction in tumor size in mice.

6 Apr 2006

A genomic signature of 254 genes predicting clinical outcome in Primary Cutaneous Melanoma identified

EORTC Melanoma Group researchers have identified a genomic signature predicting clinical outcome in Primary Cutaneous Melanoma, after patients having undergone standard treatment.

6 Apr 2006

MIT look at how cells make life-or-death decisions

The biological processes underlying diseases such as rheumatoid arthritis and cancer are fundamentally linked, and should be linked in how they are treated with drugs, a series of MIT studies indicates.

6 Apr 2006

Researchers aim to develop instrument to help physicians estimate risk for developing lung cancer

Physicians have little to help them predict development of lung cancer in their patients - even a history of heavy smoking doesn't really help, since only a small fraction of lifetime smokers develops the cancer.

6 Apr 2006

Inflammation cuts both ways

Inflammation cuts both ways. When invaded by an infectious agent, for example, the body calls on the forces of inflammation to fight and defeat the intruder.

6 Apr 2006

Vegetables slow growth of prostate cancer in mice

Chemicals in cruciferous vegetables, such as broccoli, watercress, cabbage and cauliflower, appear to stop human prostate cancer cells from growing in mice by affecting the expression of proteins, says a University of Pittsburgh Cancer Institute study

6 Apr 2006

Ingredient in red peppers inhibits prostate cancer in laboratory studies

Capsaicin is the pungent ingredient in red peppers and is presently used as a topical pain reliever. Now, a new study shows it may be justified to evaluate capsaicin for inhibiting prostate cancer (CaP) in patients.

5 Apr 2006

High glucose-uptake tumors can be identified with PET scans

Cervical cancers that take up a lot of blood sugar, or glucose, are more resistant to treatment than those that are less glucose-hungry, according to research at Washington University School of Medicine in St. Louis.

4 Apr 2006

New mechanism that initiates metastasis

Researchers have known for years that the enzyme MMP-9 plays a key role in the spread of colorectal cancer. Now, scientists at Jefferson Medical College in Philadelphia have found out how the enzyme helps initiate the process, known as metastasis.

4 Apr 2006

First study of uterine fibroid embolization to treat post-menopausal women

The first study of uterine fibroid embolization to treat post-menopausal women shows that the non-surgical treatment was technically successful in 100 percent of patients, and improved bulk-related symptoms in 92 percent of the women.

4 Apr 2006

Johns Hopkins scientists identify genes in fruitflies that may shed light on human cancer spread

By searching through all the genes in the fruitfly genome, Johns Hopkins scientists have identified those required for a certain type of cell migration and simultaneously captured a global view of all the genes turned on when cells are on the move.

4 Apr 2006

Protein in urine may point to more sensitive screening tests for women with ovarian cancer

According to the National Cancer Institute, ovarian cancer causes more deaths than any other cancer of the female reproductive system. An estimated 20,180 new cases of ovarian cancer are expected in the United States this year.

4 Apr 2006

Radiofrequency ablation is as effective as surgery for small liver tumors

Three-year data shows that radiofrequency ablation is as effective as surgical resection for overall survival and tumor recurrence, for the treatment of single small hepatocellular carcinoma in patients with liver cirrhosis, according to a study presented at the Society of Interventional Radiology's 31st Annual Scientific Meeting.

4 Apr 2006

Panitumumab shows promise for patients with colorectal cancer

Results from a Phase III study of a new drug show promise for patients with colorectal cancer that has spread to other parts of the body, according to a study presented during the 97th Annual Meeting of the American Association for Cancer Research.

4 Apr 2006