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First evidence of the molecular link between inflammation and cancer

The investigators found that a gene called I-kappa-B kinase (IKK beta), a pro-inflammatory gene, acts differently in two cell types to cause cancer. When IKK beta was deleted, the cancer incidence and tumor growth in mice was decreased by nearly 80 percent.

5 Aug 2004

New gene-silencing technique

A new gene-silencing technique that takes place in the nucleus of human cells, has been demonstrated by researchers at the University of California, San Diego (UCSD) School of Medicine and the VA San Diego Healthcare System.

5 Aug 2004

Smart drug that targets cancer cells in the brain following removal of a tumor

The use of a "smart" drug that targets cancer cells in the brain following removal of a tumor may provide treatment that can extend the survival of people with the most common form of primary malignant brain tumor, glioblastoma multiforme (GBM).

3 Aug 2004

Successfully cloning mice from an advanced melanoma cell

Nature can reset the clock in certain types of cancer and reverse many of the elements responsible for causing malignancy, reports a research team led by Whitehead Institute Member Rudolf Jaenisch, in collaboration with Lynda Chin from Dana Farber Cancer Institute.

3 Aug 2004

Recommendation against the use of chemotherapy sensitivity and resistance assays

A new technology assessment from the American Society of Clinical Oncology states that the use of chemotherapy sensitivity and resistance assays (CSRAs) to select chemotherapeutic agents for cancer patients should not be undertaken outside of the clinical trial setting.

3 Aug 2004

Adhering to established guidelines improves survival and reduces the risk of breast cancer

The first study to compare survival between women with breast cancer whose treatment was based on consensus guidelines and those whose treatment was not shows that adhering to established guidelines improves survival and reduces the risk of recurrence.

3 Aug 2004

One-third of U.S. adults use some form of alternative medicine

More than one-third of U.S. adults use some form of alternative medicine such as herbal supplements and other therapies, showed in a nationwide survey by NIH's National Center for Complementary and Alternative Medicine published in May 2004.

2 Aug 2004

New approach to cancer vaccines may eradicate skin cancer tumors

Mayo Clinic and British researchers have developed a new approach to cancer vaccines that purposely kills healthy skin cells to target the immune system against tumors. The new approach has eradicated skin cancer tumors in mice.

2 Aug 2004

Identification of PIK3CA as an oncogene associated with brain cancers opens the door to new screening processes

Hotspots in two areas of a gene that encodes a specific signaling enzyme, or kinase, are vulnerable to a variety of mutations found in five types of brain cancers, according to a report published in the August 1 issue of the journal Cancer Research.

2 Aug 2004

Miniature spectroscopic instruments and software to look at changes that occur within the cells and tissue of the brain

When molecules in cells are stimulated by light, they respond by becoming excited and re-emitting light of varying colors (fluorescence) that can be captured and measured by highly sensitive optical equipment.

2 Aug 2004

The p53 transcription factor plays a vital role in preventing cancer onset

Researchers at the Uppsala Branch of the Ludwig Institute for Cancer Research have discovered that the transcription factor Yin Yang 1 (YY1) is a novel regulator of the tumor suppressor p53, which is inactivated in at least half of all human cancers.

2 Aug 2004

New surgical technique for larynx reconstruction

Professor Pierre Delaere (Otorhinolaryngology Department, K.U.Leuven) has in the past decade developed a new surgical technique for larynx reconstruction.

29 Jul 2004

Alimta receives positive endorsement for lung cancer approval from FDA Advisory Committee

Eli Lilly and Company have announced that the Oncologic Drugs Advisory Committee (ODAC) of the U.S. Food and Drug Administration positively endorsed Alimta® (pemetrexed), an antifolate, for accelerated approval in the second-line treatment of non-small cell lung cancer.

29 Jul 2004

Combination of hormonal therapy, radioactive seed implant and external beam radiation therapy increases chance of cancer cure

High-risk prostate cancer patients who undergo a combination of hormonal therapy, radioactive seed implant (also called brachytherapy) and external beam radiation therapy are shown to have an increased chance of cancer cure

29 Jul 2004

Further evidence about how estrogen helps activate breast cancer

A UC Irvine researcher has found a novel tumor- suppressor function for a gene that, when mutated, often triggers breast cancer in women.

29 Jul 2004

Women with a history of cancer in their family are better off having MRI scans instead of mammograms

New research by Mieke Kriege at the Department of Medical Oncology, Rotterdam Family Cancer Clinic suggests that women with a history of cancer in their family are better off having MRI scans instead of mammogram's.

28 Jul 2004

Possible inherited component for lung cancer

Researchers have discovered a possible inherited component for lung cancer, a disease normally associated with external causes, such as cigarette smoking.

27 Jul 2004

Physical symptoms such as nausea and shortness of breath, may predict shorter survival for patients with terminal cancer

A new study published July 26, 2004 in the online edition of CANCER, a peer-reviewed journal of the American Cancer Society, finds a patient's symptoms and results of quality of life assessments may provide important clues to an individual patient's prognosis. Psychosocial factors, such as anxiety or spiritual distress, did not predict shorter survival.

26 Jul 2004

Preliminary tests of the new method, which can detect cancer in a sample with as few as 50 cells

Finding cancer in a tiny drop of body fluid containing relatively few cells now may be possible with a new method of analyzing multiple genes in small samples of DNA, the cellular building blocks of our genetic code.

23 Jul 2004

Bladder-sparing treatment shows promise against cancer

For patients with invasive bladder cancer, treatment has typically meant an operation to remove the bladder and nearby organs. This requires up to a week in the hospital and leaves patients with a reconstructed bladder or urostomy bag.

21 Jul 2004

Tumor News and Research

First evidence of the molecular link between inflammation and cancer

New gene-silencing technique

Smart drug that targets cancer cells in the brain following removal of a tumor

Successfully cloning mice from an advanced melanoma cell

Recommendation against the use of chemotherapy sensitivity and resistance assays

Adhering to established guidelines improves survival and reduces the risk of breast cancer

One-third of U.S. adults use some form of alternative medicine

New approach to cancer vaccines may eradicate skin cancer tumors

Identification of PIK3CA as an oncogene associated with brain cancers opens the door to new screening processes

Miniature spectroscopic instruments and software to look at changes that occur within the cells and tissue of the brain

The p53 transcription factor plays a vital role in preventing cancer onset

New surgical technique for larynx reconstruction

Alimta receives positive endorsement for lung cancer approval from FDA Advisory Committee

Combination of hormonal therapy, radioactive seed implant and external beam radiation therapy increases chance of cancer cure

Further evidence about how estrogen helps activate breast cancer

Women with a history of cancer in their family are better off having MRI scans instead of mammograms

Possible inherited component for lung cancer

Physical symptoms such as nausea and shortness of breath, may predict shorter survival for patients with terminal cancer

Preliminary tests of the new method, which can detect cancer in a sample with as few as 50 cells

Bladder-sparing treatment shows promise against cancer

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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