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How to beat throat cancer

Rochesterian Jim Toole is looking forward to a warm summer filled with hearty picnic barbecues after beating throat cancer.

16 Apr 2004

Mayo Clinic debunks myths cancer myths

Believing cancer myths can be dangerous to your health, because they could prevent you from having the tests and treatments needed to detect and treat cancer.

16 Apr 2004

New gene presents a potent new target for breast cancer therapy

A gene known to promote longevity in animals has now been discovered to encode a tumor suppressor – a protein that helps prevent cancer, according to a study by a team of scientists from The University of Texas M. D. Anderson Cancer Center. The new gene, which was inactivated in two-thirds of patients studied, presents a potent new target for breast cancer therapy, the researchers say.

16 Apr 2004

New insights into how tumors neutralize CD8 T cells

Scientists have speculated that this may be because the immune response is not strong enough, or because it does not last long enough to have an effect. Hence the increasing efforts to develop cancer vaccines that induce, strengthen, and increase the duration of immunological attack against cancer cells.

16 Apr 2004

Cancer-specific protein offers new target for the development of melanoma vaccine

Scientists from the Cancer Vaccine Collaborative (CVC) have discovered that the cancer-specific protein, SSX-2, induces a spontaneous immunological reaction against cancer cells in melanoma patients, offering a new target for the development of a therapeutic melanoma vaccine. SSX-2 is the prototype of the SSX family, and is part of a larger group of proteins known as cancer/testis (CT) antigens.

16 Apr 2004

Breast cancer treatment based on MIT radar research

A breast cancer treatment based on MIT radar research that was originally aimed at detecting space-borne missiles is showing promise in the final phase of clinical testing.

16 Apr 2004

Cinnamon's role as an insulin substitute in type II diabetes

Cinnamon may be more than a spice – it may have a medical application in preventing and combating diabetes. Cinnamon may help by playing the role of an insulin substitute in type II diabetes, according to cellular and molecular studies at the University of California, Santa Barbara, Iowa State University and the U.S. Department of Agriculture.

14 Apr 2004

Lung tumor therapies improved by combining scanning technologies

Physicians targeting lung tumors for radiation therapy can substantially improve their aim by combining data from two scanning techniques, according to Washington University researchers at Siteman Cancer Center and Barnes-Jewish Hospital in St. Louis.

14 Apr 2004

Extended lymph node dissection fails to increase survival among gastric cancer patients

Extended lymph node dissection – a treatment for gastric cancer involving the surgical removal of lymph nodes near the tumor, in distant areas of the stomach, and in some cases, in combination with the removal of the spleen and pancreas tail – has shown no long-term survival benefit for gastric cancer patients, according to the largest randomized trial of limited and extended lymph node dissection among this population.

13 Apr 2004

Extended lymph node dissection, a treatment for gastric cancer

12 Apr 2004

Green tea helps kill cells of the most common leukemia

Mayo Clinic researchers have discovered that a component in green tea helps kill cells of the most common leukemia in the United States.

12 Apr 2004

US Study Suggests New Approach to Breast Cancer Needed

Women with early-stage breast cancer face three late breast cancer consequences: disease recurrence within the conserved breast, development of a contralateral breast cancer, and manifestation of distant metastases. Although local therapy with surgery and radiotherapy is used to minimize the first possibility, adjuvant systemic therapy may theoretically reduce the likelihood of all three events.

11 Apr 2004

Results of Creutzfeldt-Jakob disease research in people who received human growth hormone from cadavers

The largest study of its kind, designed to track the development of Creutzfeldt-Jakob disease in people who received human growth hormone from cadavers, has found that the vast majority of those who received the hormone did not contract the fatal condition. However, some recipients (26 out of approximately 7,700) did develop the disease.

7 Apr 2004

FDA accepts REMICADE® (infliximab) for the treatment of early rheumatoid arthritis

Centocor, Inc., announced today that the U.S. Food and Drug Administration (FDA) has accepted its filing of a supplemental Biologics License Application (sBLA) for REMICADE® (infliximab) as first-line therapy, in combination with methotrexate, for the treatment of early rheumatoid arthritis (RA) patients with moderately-to-severely active disease. REMICADE®, in combination with methotrexate, is currently indicated in the U.S. for reducing signs and symptoms, inhibiting the progression of structural damage and improving physical function in patients with moderately-to-severely active RA who have had an inadequate response to methotrexate alone.

6 Apr 2004

Women treated with radiation therapy to cure Wilms tumor can have healthy babies if entire pelvis was not irradiated

Women who were treated with radiation therapy to cure Wilms tumor as a child can go on to have healthy babies so long as their entire pelvis was not irradiated, according to a new study in the April 2004 issue of the International Journal of Radiation Oncology-Biology-Physics, the official journal of ASTRO, the American Society for Therapeutic Radiology and Oncology.

5 Apr 2004

NeoRx Corporation acquires worldwide rights to platinum-based anti-cancer agent

NeoRx Corporation today announced that it has acquired from AnorMED Inc. the worldwide exclusive rights, excluding Japan, to develop, manufacture and commercialize AMD473, a platinum-based anti-cancer agent. AMD473 has been administered to more than 500 cancer patients in phase I and phase II clinical trials, demonstrating anti-cancer activity in a wide range of tumors and a manageable safety profile. NeoRx expects to initiate clinical studies of AMD473 in one or more cancer indications in the second half of this year.

5 Apr 2004

New center enables genetic treatments and advances

A new state-of-the-art research facility dedicated to helping produce modified cells for treatment of cancer and other diseases recently opened at the Siteman Cancer Center.

1 Apr 2004

DakoCytomation has acquired exclusive worldwide rights to develop and commercialize pharmacogenomic diagnostic tests in the field of oncology

Human Genome Sciences, Inc. announced today a license agreement with DakoCytomation A/S (Glostrup, Denmark), under which DakoCytomation has acquired exclusive worldwide rights to develop and commercialize pharmacogenomic diagnostic tests in the field of oncology based on the TRAIL Receptor-1 (TRAIL-R1) and TRAIL Receptor-2 (TRAIL-R2) proteins.

31 Mar 2004

Research team has found a new way to streamline gene isolation to determine their functions

A single strand of plant or animal DNA may contain tens of thousands of genes, each programmed to produce a specific protein essential for the growth or survival of the organism. The challenge for geneticists is to isolate individual genes and determine their function -- a painstaking process often requiring years of laboratory trial and error.

31 Mar 2004

Faster new cloning technique - transcript-based cloning

A single strand of plant or animal DNA may contain tens of thousands of genes, each programmed to produce a specific protein essential for the growth or survival of the organism. The challenge for geneticists is to isolate individual genes and determine their function – a painstaking process often requiring years of laboratory trial and error.

30 Mar 2004