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New genetic test can predict clinical outcomes in glioblastoma patients

New research proves that a change in a particular gene can identify which patients with a specific kind of brain cancer will respond better to treatment. Testing for the gene can distinguish patients with a more- or less-aggressive form of glioblastoma, the most common and an often-fatal type of primary brain cancer, and help guide therapy, the researchers say.

1 Jun 2011

Lymphoma vaccine extends disease-free survival by 14 months

A lymphoma vaccine uniquely tailored for each patient extends disease-free survival by 14 months, with signs of an even better response for patients with a specific biological marker, a team led by scientists at The University of Texas MD Anderson Cancer Center reported today in the online version of Journal of Clinical Oncology.

1 Jun 2011

IPSOGEN announces two studies on Genomic Grade test to be presented at ASCO 2011

IPSOGEN SA today announces that two studies on the Genomic Grade test will be presented at the American Society for Clinical Oncology Annual Meeting, that will take place June 3-7, 2011, in Chicago, Ill, USA.

1 Jun 2011

Type II diabetes drug may slow or stop breast cancer tumor metastasis

A protein activated by certain drugs already approved for treating Type II diabetes may slow or stop the spread of breast tumors.

1 Jun 2011

Centocor Ortho Biotech, AVEO sign license deal to develop, commercialize RON-targeted antibodies

AVEO Pharmaceuticals, Inc. today announced it has entered into an exclusive license agreement with Centocor Ortho Biotech Inc. for the worldwide development and commercialization of AVEO's internally-discovered antibodies targeting the RON receptor.

1 Jun 2011

Chronic fatigue syndrome and mouse virus – no association

An earlier study published in 2009 had claimed that a mouse virus was the cause of chronic fatigue syndrome. New evidence suggests that this assumption is wrong. According to latest evidence the earlier study findings were likely based on contaminated lab samples, US researchers said Tuesday.

1 Jun 2011

Fraunhofer MEVIS' novel brain procedure helps minimize patient-specific surgical risks

To increase patient safety in clinical practice and minimize risks and damage that may arise during surgery, computer support and digital medical imaging are key technologies. Before brain operations, neurosurgeons can now evaluate patient-specific surgical risks, achieve increased safety, and avoid unacceptable risks.

30 May 2011

New insights into pathogenesis and treatment of hereditary breast, ovarian cancer

5% to 10% of all breast cancers are monogenic in origin. In other words, there is a mutation of the genes BRCA1, BRCA2 or other high-risk genes. In this edition of Deutsches Ärzteblatt International, Alfons Meindl of the Klinikum rechts der Isar and coauthors report on new insights into the pathogenesis and treatment of hereditary breast and ovarian cancer and newly-discovered risk genes.

30 May 2011

Scientists identify new molecular pathway that may combat retinal disease, cancers

Scientists identify in the journal Nature a new molecular pathway used to suppress blood vessel branching in the developing retina - a finding with potential therapeutic value for fighting diseases of the retina and a variety of cancers.

30 May 2011

OVA1 more effective than CA 125 test in evaluating likelihood of ovarian cancer

A paper published in the June issue of Obstetrics & Gynecology demonstrated that adding OVA1 to a physician's preoperative assessment of a woman's ovarian mass would identify more ovarian cancers than a physician's preoperative assessment alone.

From Quest Diagnostics 27 May 2011

Transgenomic secures exclusive license from Montefiore for cancer predictive markers

Transgenomic, Inc. announced today that it has acquired an exclusive worldwide license to Montefiore Medical Center's patent application, "Method of Determining the Sensitivity of Cancer Cells to EGFR Inhibitors including cetuximab, panitumumab and erlotinib".

27 May 2011

Innovations in diagnosis and treatment for esophageal cancer

In recent years, the number of cases of adenocarcinoma of the esophagus (or gullet) has been on the rise. At the same time, however, new ways of treatment are improving the outlook for patients. In the current issue of Deutsches Ärzteblatt International, Angelika Behrens and her working group report on innovations in diagnosis and treatment.

27 May 2011

Lactate shuttle also exists in human tumors

Researchers at the Kimmel Cancer Center at Jefferson have shed new light on the longstanding conundrum about what makes a tumor grow-and how to make it stop. Interestingly, cancer cells accelerate the aging of nearby connective tissue cells to cause inflammation, which ultimately provides "fuel" for the tumor to grow and even metastasize.

27 May 2011

BioDiscovery, Affymetrix enter co-marketing agreement for OncoScan FFPE Express Service

Affymetrix, Inc. today announced a co-marketing agreement naming BioDiscovery, Inc. its preferred software provider for Affymetrix OncoScan FFPE Express Service data analysis.

27 May 2011

Leukemia, psoriasis drugs may treat vascular diseases

A drug that has been on the market for decades to treat leukemia and skin disorders such as acne and psoriasis may be a possible therapy for vascular diseases, including atherosclerosis and hypertension, which can lead to heart attack or stroke.

27 May 2011

Tacrolimus prevents breast cancer growth in pre-clinical studies

Tacrolimus, a drug that is commonly used to prevent organ transplantation rejection, inhibits breast cancer growth in pre-clinical studies. The finding from UNC scientists was reported in the May 26th PLoS ONE.

27 May 2011

Pro-Pharmaceuticals announces name change to Galectin Therapeutics

Pro-Pharmaceuticals, Inc. today announced that it has changed its name to Galectin Therapeutics Inc. to more accurately reflect the Company's core expertise in galectin science and its leading platform for the creation of galectin inhibitors to treat serious diseases including fibrosis and cancer.

27 May 2011

Turkey tail mushrooms effective in prostate cancer: study

Preliminary studies have shown that mushrooms used in Asia for medicinal purposes vanquished prostate tumor successfully in mice.

26 May 2011

Boehringer Ingelheim's new afatinib-cetuximab phase Ib data in NSCLC presented at ASCO 2011

Boehringer Ingelheim Pharmaceuticals, Inc. will present new phase Ib data at the 2011 American Society of Clinical Oncology annual meeting in Chicago that indicates combining its investigational therapy afatinib with cetuximab at the maximum tested dose controlled disease in all (n=22) treated epidermal growth factor receptor (EGFR)-mutation positive patients with non-small cell lung cancer who developed acquired resistance to treatment with a reversible EGFR tyrosine kinase inhibitor.

26 May 2011

ASTRO to honor two radiation oncologists with 2011 Gold Medal award

The American Society for Radiation Oncology has selected K. Kian Ang, MD, PhD, FASTRO, and Bernard Cummings, MB, ChB, FASTRO, as the Society's 2011 Gold Medal recipients.

26 May 2011

Tumor News and Research

New genetic test can predict clinical outcomes in glioblastoma patients

Lymphoma vaccine extends disease-free survival by 14 months

IPSOGEN announces two studies on Genomic Grade test to be presented at ASCO 2011

Type II diabetes drug may slow or stop breast cancer tumor metastasis

Centocor Ortho Biotech, AVEO sign license deal to develop, commercialize RON-targeted antibodies

Chronic fatigue syndrome and mouse virus – no association

Fraunhofer MEVIS' novel brain procedure helps minimize patient-specific surgical risks

New insights into pathogenesis and treatment of hereditary breast, ovarian cancer

Scientists identify new molecular pathway that may combat retinal disease, cancers

OVA1 more effective than CA 125 test in evaluating likelihood of ovarian cancer

Transgenomic secures exclusive license from Montefiore for cancer predictive markers

Innovations in diagnosis and treatment for esophageal cancer

Lactate shuttle also exists in human tumors

BioDiscovery, Affymetrix enter co-marketing agreement for OncoScan FFPE Express Service

Leukemia, psoriasis drugs may treat vascular diseases

Tacrolimus prevents breast cancer growth in pre-clinical studies

Pro-Pharmaceuticals announces name change to Galectin Therapeutics

Turkey tail mushrooms effective in prostate cancer: study

Boehringer Ingelheim's new afatinib-cetuximab phase Ib data in NSCLC presented at ASCO 2011

ASTRO to honor two radiation oncologists with 2011 Gold Medal award

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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