Type I Diabetes News and Research

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Discovery may lead to new class of diabetes drugs

A multidisciplinary team led by researchers at the University of California, San Diego has determined the structure of a protein found in cells that shows potential as a target for the development of new drugs to treat diabetes.

30 Aug 2007

Brain's impaired ability to sense glucose might play role in type 2 diabetes

New findings from studies in mice suggest that defects in the brain's ability to respond to glucose play a role in the development of non-insulin dependent (type 2) diabetes, and that a high-fat diet may contribute to impairing brain cells' ability to regulate glucose throughout the body.

30 Aug 2007

Third factor identified in obesity-induced Type 2 diabetes

In cases of Type 2 diabetes, the body's cells fail to appropriately regulate blood glucose levels.

30 Aug 2007

Study looks at salsalate for type 2 diabetes

The University of Illinois at Chicago is one of 16 sites in the United States taking part in the first large-scale study to test a promising approach to lowering blood glucose levels in adults with type 2 diabetes.

24 Aug 2007

New diabetes mellitus clinical practice guidelines

The American Association of Clinical Endocrinologists (AACE) has announced the release of its medical guidelines for the diagnosis and management of diabetes mellitus.

24 Aug 2007

Insulin pens may offer diabetics substantial savings

Diabetics who need to switch from oral medications to insulin could reduce their annual healthcare costs up to $17,000 by using an insulin pen instead of a syringe to deliver their daily dose of medication.

22 Aug 2007

Tumors use enzyme to recruit regulatory T-cells and suppress immune response

One way tumors fly under the radar of the immune system is by using IDO, an enzyme used by fetuses to help avoid rejection, to recruit powerful regulatory T cells that turn down the immune response, researchers say.

17 Aug 2007

Sirtuin protein instrumental in fat production and metabolism

A new Joslin Diabetes Center-led study has identified a protein found in fat cells that may play a major role in how fat is produced and stored, offering a new target for treatments to prevent obesity and reduce the risk for type 2 diabetes.

17 Aug 2007

Women with a history of gestational diabetes may have higher risk of developing pancreatic cancer

Pregnancies in Jerusalem in the 1960s and 1970s may hold vital clues about how pancreatic cancer and diabetes are linked.

17 Aug 2007

Cytokines shown to be a cause of type 2 diabetes

In the first large scale, multiethnic study of its kind, researchers at UCLA have confirmed the role played by three particular molecules known as cytokines as a cause of Type 2 diabetes, and further, have identified these molecules as early biological markers that may be used to more accurately predict future incidences of diabetes among apparently healthy individuals.

16 Aug 2007

Strengthened warnings on some type 2 diabetes drugs

The U.S. Food and Drug Administration has announced manufacturers of certain drugs approved to treat Type 2 diabetes have agreed to add a stronger warning on the risk of heart failure, a condition that occurs when the heart does not adequately pump blood.

16 Aug 2007

Healthy eating for type 2 diabetes

Myths abound when it comes to diabetes and food - one of the most common being that there is a "diabetes diet" that prohibits sugar and other items.

16 Aug 2007

Eating junk food during pregnancy and breastfeeding gives offspring taste for junk food

Mothers who eat junk food during pregnancy and breastfeeding may be putting their children at risk of overeating and developing obesity, according to a study funded by the Wellcome Trust and carried out at the Royal Veterinary College, London.

16 Aug 2007

Pregnant women advised to cut out junk food for their child's sake

British researchers are warning pregnant women that a penchant for junk food may be condemning their children to crave the same diet.

14 Aug 2007

MS patients given hope with new vaccine treatment

Canadian researchers have developed a vaccine to stop the progression of multiple sclerosis (MS) and they say encouraging results have already been seen.

14 Aug 2007

Mitochondrial DNA variants are linked to risk factors for type 2 diabetes

Researchers report for the first time that genetic variants in mitochondria,energy-producing structures harboring DNA that are inherited only from the mother,are directly linked to metabolic markers for type 2 diabetes.

13 Aug 2007

Staggering costs of end-stage renal disease in U.S.

Recent progress in the prevention and treatment of end-stage renal disease (ESRD) in the United States give reason for "cautious optimism," but skyrocketing costs are a major concern, according to a Special Article in the October Journal of the American Society of Nephrology.

12 Aug 2007

Writing off Avandia may be premature

Rosiglitazone, a drug marketed by GlaxoSmithKline as Avandia, for the treatment of type 2 diabetes, came under fire after an article published online May 21 by the New England Journal of Medicine linked it to significantly increased risk of heart attack and cardiovascular death.

12 Aug 2007

The role of estrogens and polyphenols in hypertension and diabetes

Menopausal women are at relatively high risk for memory loss, high blood pressure (hypertension) and diabetes.

12 Aug 2007

FGFR4 gene plays a complex role in obesity, fatty liver and diabetes

Researchers at the Texas A&M Health Science Center Institute of Biosciences and Technology at Houston have found that a gene in the liver and elsewhere in the body, when inhibited or increased, affects fatty liver and diabetes but does not alleviate both diseases at once.

11 Aug 2007