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Biomarker predicts severity of SARS-CoV-2 infection in patients

A new study investigates a biomarker to predict the severity of disease in patients infected with SARS-CoV-2.

20 Oct 2021

Suggested mechanism of SARS-CoV-2 infection inhibition by Mitoxantrone

A group of researchers performed a drug repurposing screen on an FDA-approved anti-cancer drug named Mitoxantrone.

20 Oct 2021

Mutation of cysteine residues in NRP1 reduces SARS-CoV-2 spike protein entry into cells

Researchers have been investigating altered protein conformations in variants of concern to provide further insight for future therapies against COVID-19.

14 Oct 2021

Research reveals 3D structure of cell receptor with critical role in health and disease

Cells communicate with their environment via receptors on their surface. When a protein approaches these receptors, they can pass along a message to the inside of the cell, for example the instruction to grow which can lead to tumor formation.

13 Oct 2021

Cancer drug can restore memory and cognitive function in mice with Alzheimer’s symptoms

A drug commonly used to treat cancer can restore memory and cognitive function in mice that display symptoms of Alzheimer's disease, new UBC research has found.

5 Oct 2021

Osimertinib offers a hint of added benefit for NSCLC patients who have received adjuvant chemotherapy

Osimertinib was the first drug to be approved for adjuvant treatment after complete tumour resection in adults with stage IB to IIIA non-small cell lung cancer (NSCLC).

2 Oct 2021

New study clears a pharmacologic hurdle in developing molecularly targeted therapies for AML

New research from Johns Hopkins Kimmel Cancer Center investigators shows why some drugs in clinical trials for treating a form of acute myeloid leukemia (AML) often fail and demonstrates a way to restore their effectiveness.

27 Sep 2021

Potential covalent SARS-CoV-2 spike protein inhibitors

There remains a significant need for new and effective drugs that can be used to treat COVID-19.

23 Sep 2021

Study shows how SARS-CoV-2 viral proteases can be targeted to stop virus replication

Researchers at the University of Liverpool have shown how SARS-CoV-2 viral proteases attack the host cell, and how this can be targeted to stop virus replication in cell culture using existing drugs.

21 Sep 2021

Novel combination therapy approach to keep leukemia at bay

In chronic leukemias, blocking the overactive kinase JAK2 by a targeted therapy approach is only mitigating the patients' symptoms, but cannot truly change the course of the disease.

16 Sep 2021

Grouping EGFR mutations provides an accurate way to match lung cancer patients to the right drugs

Researchers from The University of Texas MD Anderson Cancer Center have discovered that grouping epidermal growth factor receptor (EGFR) mutations by structure and function provide an accurate framework to match patients with non-small cell lung cancer (NSCLC) to the right drugs.

16 Sep 2021

Implications of persistent SARS-CoV-2 infection in patients with lymphoid malignancies

In a recent study, scientists attempt to understand persistent COVID-19 and its implications in patients with hematologic malignancies.

6 Sep 2021

Scientists identify novel mechanism that links genetic defect in IBD patients to gut leakiness

A team of researchers led by a biomedical scientist at the University of California, Riverside, has identified a novel mechanism by which loss-of-function mutations in the gene PTPN2, found in many patients with inflammatory bowel disease, or IBD, affect how intestinal epithelial cells maintain a barrier.

3 Sep 2021

Tyrosine News and Research

Biomarker predicts severity of SARS-CoV-2 infection in patients

Suggested mechanism of SARS-CoV-2 infection inhibition by Mitoxantrone

Mutation of cysteine residues in NRP1 reduces SARS-CoV-2 spike protein entry into cells

Research reveals 3D structure of cell receptor with critical role in health and disease

Cancer drug can restore memory and cognitive function in mice with Alzheimer’s symptoms

Osimertinib offers a hint of added benefit for NSCLC patients who have received adjuvant chemotherapy

New study clears a pharmacologic hurdle in developing molecularly targeted therapies for AML

Potential covalent SARS-CoV-2 spike protein inhibitors

Study shows how SARS-CoV-2 viral proteases can be targeted to stop virus replication

Novel combination therapy approach to keep leukemia at bay

Grouping EGFR mutations provides an accurate way to match lung cancer patients to the right drugs

Implications of persistent SARS-CoV-2 infection in patients with lymphoid malignancies

Scientists identify novel mechanism that links genetic defect in IBD patients to gut leakiness

Researchers develop new photodynamic therapy for the treatment of deep tumors

Two studies on gastrointestinal stroma tumors describe advances that may lead to new treatments

Study: PirB inhibits the self-renewal and differentiation capacities of neural stem cells

Severe COVID-19 characterized by phosphorylation of STAT1

New approach could be a useful tool in the fight against cancer drug resistance

SARS-CoV-2 variants and their ability to infect mice

Research suggests potential new treatment strategy for phenylketonuria

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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