VEGF News and Research

RSS

VEGF is a substance made by cells that stimulates new blood vessel formation. Also called vascular endothelial growth factor.

Researchers shed new light on how Toxoplasma parasite damages the human eye

One third of the world population is infected with the parasite -Toxoplasma- which causes a common eye infection called ocular toxoplasmosis. Researchers have shed new light on how an infection with the parasite causes a distinctive lesion in the retina.

30 Sep 2019

Johns Hopkins researchers develop new way to deliver sight-saving gene therapy to the retina

In experiments with rats, pigs and monkeys, Johns Hopkins Medicine researchers have developed a way to deliver sight-saving gene therapy to the retina.

From Johns Hopkins Medicine 30 Sep 2019

New biomarkers help predict response to treatment in common brain tumor

Many scientists have noted that there is a link between inflammation or the immune response, and patient survival. One such possible relationship is the association of blood markers and the prognosis in the brain tumor called medulloblastoma.

16 Sep 2019

Drugs used to treat retinal diseases are excreted into human breast milk, study finds

Certain drugs used to treat retinal diseases are excreted into breast milk, raising possible safety concerns for developing infants, suggests a first-of-its-kind study led by St. Michael's Hospital in Toronto and published in Ophthalmology.

15 Sep 2019

Protein found in the eye can protect against diabetic retinopathy

Researchers at Joslin Diabetes Center have shown that a protein found in the eye can protect against and potentially treat diabetic eye disease.

4 Jul 2019

Promising new approaches in the fight against brain metastasis

Research is currently pursuing several highly promising approaches in the fight against cancers that give rise to metastases in the brain.

28 Jun 2019

Scientists use advanced imaging to track brain tumor 'turncoats'

Glioblastomas, the deadliest type of brain tumor in adults, attract "turncoats." These are macrophages, a type of immune cell, which promote tumor progression and mask tumors from the immune system's scrutiny.

26 Jun 2019

Researchers find a potential modulator in revascularization of pancreatic islets

The first cause of the loss of functionality in transplanted pancreatic islets is the low capacity to create new vessels to allow the arrival of nutrients in the cells.

20 Jun 2019

Study uncovers potential new way to prevent common pregnancy-related complications

About 1 in 10 pregnant women experience placenta abnormalities that lead to life-threatening preeclampsia (hypertension), preterm labor and fetal growth problems, but finding effective treatments to effectively prevent or reverse these conditions has so far been elusive.

19 Jun 2019

New implant technology safely minimizes injections for people with macular degeneration

In a clinical trial of 220 people with “wet” age-related macular degeneration, Johns Hopkins Medicine researchers, collaborators from many sites across the country, and Genentech in South San Francisco have added to evidence that using a new implant technology that continuously delivers medication into the eyes is safe and effective in helping maintain vision and reduces the need for injections in the eyes.

From Johns Hopkins Medicine 14 Jun 2019

New therapeutic approach utilizes endogenous processes to enhance cardiac repair

Myocardial infarction results in the localized death of the muscle cells that are essential for the heart's pumping function.

12 Jun 2019

'Eye-in-a-dish' model helps scientists to uncover 'surprising' AMD gene variant

Researchers have discovered a new genetic variant responsible for blood vessel dysregulation in the development of age-related macular degeneration (AMD).

29 May 2019

Prostate cancer marker activates growth factors that contribute to tumor spread

A new study indicates that PSA, a prostate cancer marker, is one of the catalysts that activate vascular endothelial and lymphangiogenic growth factors which contribute to the spread of cancer.

25 May 2019

Novel approach uses magnetic beads for the treatment of preeclampsia

Preliminary laboratory tests show that functionalized magnetic beads successfully reduced blood levels of a harmful molecule that is elevated during preeclampsia, according to new research in the American Heart Association's journal Hypertension.

13 May 2019

'Eye-in-a-dish' model reveals genetic variants that may contribute to AMD

Age-related macular degeneration is one of the most common causes of vision loss in people over age 65.

10 May 2019

A new strategy for managing diabetic macular edema in people with good vision

A change to the approach for treating diabetic macular edema may be on the way, thanks to a study published today in the Journal of the American Medical Association.

2 May 2019

Experimental drug may be twice as good at fighting vision loss as previously thought

In studies with lab-grown human cells and in mice, Johns Hopkins Medicine researchers have found that an experimental drug may be twice as good at fighting vision loss as previously thought.

11 Apr 2019

Gene medication shows promise to treat spinal cord injuries

The two-gene medication has been proven to recover motor functions in rats. After several months of treatment, rodents were able to use previously paralyzed limbs. Researchers at Kazan Federal University are now seeking pre-clinical trial investment.

18 Mar 2019

Study suggests new approach to ameliorating obesity-associated metabolic abnormalities

The search by scientists to find ways to combat obesity continues. Recently, investigators have been exploring whether they can engage the lymphatic system to help regulate obesity-induced inflammation of fat (adipose) tissue and restore systemic metabolic fitness.

14 Mar 2019

Study shows therapeutic potential of VEGF-A mRNA for regenerative angiogenesis in humans

An international team of researchers from academia and the biopharma industry has published a Phase 1a/b study, showing the therapeutic potential of mRNA encoding for vascular endothelial growth factor A (VEGF-A) for regenerative angiogenesis in humans.

20 Feb 2019