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Turning on hormone tap could aid osteoporosis fight

A potential new drug that 'opens the taps' for the release of useful hormones could stimulate new bone growth - and may eventually bring relief to osteoporosis sufferers.

From The University of Manchester 16 Jul 2008

Improving understanding of cell behaviour in breast cancer

The invasion and spread of cancer cells to other parts of the body, known as metastasis, is a principal cause of death in patients diagnosed with breast cancer. Although patients with early stage, small, breast tumours have an excellent short term prognosis, more than 15 to 20 per cent of them will eventually develop distant metastases, and die from the disease. Vascular invasion - through lymphatic and blood vessels - is the major route for cancer spreading to regional lymph nodes and to the rest of the body.

15 Jul 2008

Novel approach shows potential to become an emergency treatment for heart attack patients

Researchers at The Children's Hospital of Philadelphia have manipulated cell activity that occurs during the interruption of blood flow to strongly protect heart tissue in animal studies. The finding has the potential to become an emergency treatment for heart attack patients, particularly since already existing drugs might be pressed into service to produce the protective effects.

10 Jul 2008

More research needed into effects of flavonoids and flavonoid-rich food sources on heart disease

More research is needed into food compounds which could reduce the risk of heart disease, according to a systematic review of trials carried out so far.

10 Jul 2008

Nanomaterials key to new strategies for blocking metastasis

A new treatment strategy using targeted nanoparticles to block metastasis with anti-cancer drugs leads to good results using significantly lower doses of toxic chemotherapy, with less collateral damage to surrounding tissue, according to a collaborative team of researchers at the Center of Nanotechnology for Treatment, Understanding, and Monitoring of Cancer at the University of California, San Diego. In designing this system, the investigators, led by David Cheresh, Ph.D., have identified what may become a generic method for using nanotechnology to target metastasis.

9 Jul 2008

Holey nanoparticles create new tumor imaging and therapeutic agent

Using a polymer that has both water-soluble and water-insoluble regions, a team of investigators from the Siteman Center of Cancer Nanotechnology Excellence has created a nanoparticle shaped like a bialy, a close relative of the bagel. Combining this nanoparticle with manganese, a metal that boosts magnetic resonance imaging signals, and an antibody that targets blood vessels, the investigators then created a new type of imaging agent that also has the potential to deliver drugs to tumors.

9 Jul 2008

Lowering blood pressure reduces the risk of dementia

New research suggests that lowering blood pressure in older people could reduce their chances of dementia by 13%.

8 Jul 2008

93-year old man with life threatening aneurysm treated using new fenestrated endograft stent

In a New York City metro-area first, a 93-year-old Bronx man underwent implantation of a new stent graft at NewYork-Presbyterian Hospital, the only center on the Eastern Seaboard with access to this investigational device. The new stent graft was implanted under an FDA-approved clinical trial protocol.

7 Jul 2008

Resveratrol shown to reduce age related health problems

Researchers in the U.S. have found that a compound found in grapes and red wine can significantly reduce age related health problems.

7 Jul 2008

Resveratrol mimics the beneficial effects of eating fewer calories

Large doses of a red wine ingredient can ward off many of the vagaries of aging in mice who begin taking it at midlife, according to a new report published online on July 3rd in Cell Metabolism, a Cell Press publication.

3 Jul 2008

Scientists shed new light into early mechanisms governing cardiovascular specification

The mature heart is composed by different cell types, including contractile cardiac cells, vascular cells, smooth muscle cells as well as pacemaker cells.

3 Jul 2008

Statins have unexpected effect on pool of powerful brain cells

Cholesterol-lowering drugs known as statins have a profound effect on an elite group of cells important to brain health as we age, scientists at the University of Rochester Medical Center have found. The new findings shed light on a long-debated potential role for statins in the area of dementia.

3 Jul 2008

New insight into role of statins in dementia

3 Jul 2008

Low levels of good cholesterol could signal dementia

A study by British and French scientists has revealed that the risk of dementia may increase with a lack of "good" cholesterol in middle age.

1 Jul 2008

Low levels of high-density lipoproteins linked to memory loss, dementia risk

Low levels of high-density lipoproteins (HDL) - the "good" cholesterol - in middle age may increase the risk of memory loss and lead to dementia later in life, researchers reported in Arteriosclerosis, Thrombosis and Vascular Biology: Journal of the American Heart Association.

30 Jun 2008

Low childhood IQ linked to dementia risk later in life

The researchers from Edinburgh University compared the records of 173 people who took part in the Scottish Mental Survey of 1932, a mental ability test taken by almost every child aged 11 in Scotland, they found that lower childhood IQ increased the risk of vascular dementia.

30 Jun 2008