Vascular News and Research

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Targeting of angiogenic endothelial cells at sites of inflammation by Dexamethasone Phosphate-containing RGD peptide liposomes inhibits experimental arthritis

Vascular endothelial cells (VECs) form the walls of blood vessels and play a critical role in inflammation.

4 Apr 2006

Trial of paclitaxel with or without bevacizumab as first-line therapy for locally recurrent or metastatic breast cancer

Results from a large, randomised clinical trial for patients with breast cancer show that those who received bevacizumab (Avastin.) in combination with paclitaxel (Taxol.) survived without the disease getting worse for almost twice as long as patients who received paclitaxel alone.

23 Mar 2006

Stem cells, gene therapy and allograft applications show promise for treating orthopaedic conditions

Recent advances in gene therapy, stem cells and other promising applications are offering new hope for patients and helping orthopaedic surgeons provide state-of-the-art treatment for various frame-related conditions.

23 Mar 2006

Research finds blood type, age may be pivotal in transfusion success

The controversial practice of blood transfusions for patients suffering from cardiac episodes may lead to an increased risk of mortality, and may be correlated to transfusion blood type and blood age, according to research presented at the American College of Cardiology Annual Scientific Session.

21 Mar 2006

Donepezil (Aricept) helps cognitive function in brain tumor patients after radiation

A drug that is marketed to treat Alzheimer's disease also improves cognitive function, mood and quality of life in brain tumor patients following radiation therapy, according to a research team at Wake Forest University Baptist Medical Center.

21 Mar 2006

Carotid stenting beneficial for patients with disease but no symptoms

Results from the largest-ever multi-center U.S. registry on the efficacy of carotid stenting shows that the procedure is safe in patients who are at high risk for standard surgical therapy.

20 Mar 2006

Salt substitution in rural China would cut hypertension rates

A salt substitute specially formulated to be flavourful and effective has significantly reduced blood pressure among high-risk residents of northern, rural China, where home-pickled foods are a dietary mainstay and hypertension is rampant.

15 Mar 2006

Creative new therapies for atherosclerotic disease

Patients with a build-up of plaque in arteries in the heart, brain and leg face a high risk of major cardiovascular complications.

14 Mar 2006

Australian researchers find key 'go-betweeen' in heart disease

Medical researchers at the University of New South Wales (UNSW) - Australia, have shed light on a little-known mechanism involved in the thickening of arteries, a process associated with heart disease.

13 Mar 2006

Renal and extrarenal predictors of nephrectomy from The National Trauma Data Bank reviewed

The management of renal trauma has become increasingly conservative with multiple series showing renal preservation after high grade injury.

13 Mar 2006

B vitamins and folic acid don't cut the risk of further heart attacks

Scientists have found that levels of the amino acid homocysteine may be high in people destined for a heart attack or stroke, and some studies in the past have linked homocysteine to an increased risk of heart disease.

13 Mar 2006

Sirolimus-releasing stents more effective than vascular brachytherapy for treating restenosis within a stent

David R. Holmes, Jr., M.D., of Mayo Clinic, Rochester, Minn., and colleagues with the SISR trial compared the use of vascular brachytherapy (VBT - intra-coronary radiation therapy) with implantation of the sirolimus-eluting stent for the treatment of restenosis occurring within a previously placed bare-metal stent

13 Mar 2006

Using a growth factor to stimulate production of circulating endothelial progenitor cells improves cell production and mobility in arterial disease

Using a growth factor to stimulate production of circulating endothelial progenitor cells increases the numbers of these vascular regenerative cells, improves mobility, and potentially could improve blood vessel function in patients with peripheral arterial disease (PAD).

13 Mar 2006

Stents that release the drug paclitaxel to treat stenosis more effective than radiation therapy

Insertion of stents that release the drug paclitaxel to treat stenosis within an implanted bare-metal stent in a coronary artery reduces the risk of subsequent re-narrowing within the stent, when compared with treatment using intra-coronary radiation

13 Mar 2006

Drug-eluting stents best treatment for managing coronary restenosis

In the first published trial of its kind, a multi-center clinical study has shown that drug-eluting stents outperform the current "gold standard" radiation treatment in managing coronary restenosis and in preventing further clogging of coronary arteries.

13 Mar 2006

Depressed older adults more likely to develop mild cognitive impairment

Older adults with depressive symptoms are more likely than those without depression to develop mild cognitive impairment (MCI) within six years, according to a study conducted by researchers at the San Francisco VA Medical Center and the University of California, San Francisco.

9 Mar 2006

Taipan venom may stop excessive bleeding during vascular surgery

A blood-clotting protein in taipan venom has been identified by Queensland University of Technology PhD researcher Liam St Pierre to rapidly stop excessive bleeding during vascular surgery and major trauma.

9 Mar 2006

Exposure to fine particle air pollution significantly increases the risk for cardiovascular and respiratory disease

New data from a four-year study of 11.5 million Medicare enrollees show that short-term exposure to fine particle air pollution from such sources as motor vehicle exhaust and power plant emissions significantly increases the risk for cardiovascular and respiratory disease among people over 65 years of age.

9 Mar 2006

Short-term exposure to fine particulate matter increases hospital admissions for heart problems

Short-term exposure to fine particulate matter - the microscopic particles that pollute the air - increased hospital admissions for cardiovascular and respiratory disease among Medicare participants, according to a study of 204 U.S. urban counties conducted by researchers at the Johns Hopkins Bloomberg School of Public Health and Yale University’s environment school.

8 Mar 2006

Study may lead to ways to reduce heart attacks in diabetes patients

For people with type 2 diabetes, the death rate from a first heart attack is two to three times the death rate of patients without the disease. Similarly, patients with diabetes and ischemic (reduced blood flow) heart disease have a much higher mortality rate than the general population.

7 Mar 2006

Vascular News and Research

Targeting of angiogenic endothelial cells at sites of inflammation by Dexamethasone Phosphate-containing RGD peptide liposomes inhibits experimental arthritis

Trial of paclitaxel with or without bevacizumab as first-line therapy for locally recurrent or metastatic breast cancer

Stem cells, gene therapy and allograft applications show promise for treating orthopaedic conditions

Research finds blood type, age may be pivotal in transfusion success

Donepezil (Aricept) helps cognitive function in brain tumor patients after radiation

Carotid stenting beneficial for patients with disease but no symptoms

Salt substitution in rural China would cut hypertension rates

Creative new therapies for atherosclerotic disease

Australian researchers find key 'go-betweeen' in heart disease

Renal and extrarenal predictors of nephrectomy from The National Trauma Data Bank reviewed

B vitamins and folic acid don't cut the risk of further heart attacks

Sirolimus-releasing stents more effective than vascular brachytherapy for treating restenosis within a stent

Using a growth factor to stimulate production of circulating endothelial progenitor cells improves cell production and mobility in arterial disease

Stents that release the drug paclitaxel to treat stenosis more effective than radiation therapy

Drug-eluting stents best treatment for managing coronary restenosis

Depressed older adults more likely to develop mild cognitive impairment

Taipan venom may stop excessive bleeding during vascular surgery

Exposure to fine particle air pollution significantly increases the risk for cardiovascular and respiratory disease

Short-term exposure to fine particulate matter increases hospital admissions for heart problems

Study may lead to ways to reduce heart attacks in diabetes patients

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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