Viral Disease News and Research

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Scientists find key to strengthening immune response to chronic infection

A team of researchers from The Wistar Institute has identified a protein that could serve as a target for reprogramming immune system cells exhausted by exposure to chronic viral infection into more effective "soldiers" against certain viruses like HIV, hepatitis C, and hepatitis B, as well as some cancers, such as melanoma.

6 Aug 2009

Discovery of 'tell-tale' viral signature in blood that identifies underlying viral infection

Scientists have identified a genomic "signature" in circulating blood that reveals exposure to common upper respiratory viruses, like the cold or flu, even before symptoms appear.

6 Aug 2009

Pattern of gene expression in blood provides clues to etiology of respiratory infections

Scientists have shown that they can identify and characterize an individual's response to a respiratory viral infection by examining the pattern of gene expression in their blood.

6 Aug 2009

Discovery of potential candidate protein for cancer vaccines

Researchers at the University of Pittsburgh School of Medicine have learned that some healthy people naturally developed an immune response against a protein that is made in excess levels in many cancers, including breast, lung, and head and neck cancers. The finding suggests that a vaccine against the protein might prevent malignancies in high-risk individuals.

4 Aug 2009

New nano-gene therapy technique could fight late-stage tumors

Tiny particles carrying a killer gene can effectively suppress ovarian tumor growth in mice, according to a team of researchers from MIT and the Lankenau Institute.

31 Jul 2009

Scientists block Ebola infection in cell-culture experiments - could lead to first therapy

Researchers at the University of Texas Medical Branch at Galveston have discovered two biochemical pathways that the Ebola virus relies on to infect cells.

23 Jun 2009

Transplant drug Rapamycin stimulates immune memory

Rapamycin, a drug given to transplant recipients to suppress their immune systems, has a paradoxical effect on cells responsible for immune memory, scientists at the Emory Vaccine Center have discovered.

22 Jun 2009

HIV antibody tests unreliable for early infections in teens

A previously healthy teenager shows up at the doctor's office with a sore throat, fever, aches and general malaise. Routine blood tests are normal, an HIV test comes back negative, and the pediatrician sends the patient home with a diagnosis of acute viral infection.

21 Jun 2009

Research uncovers clues to the development of cancers in AIDS patients

In a series of recently-published articles, a research team from the University of North Carolina at Chapel Hill Lineberger Comprehensive Cancer Center has uncovered clues to the development of cancers in AIDS patients.

17 Jun 2009

Adding antiviral agent to corticosteroids to treat facial paralysis not linked to improved recovery

Adding an antiviral agent to corticosteroids for treatment of Bell's palsy (a condition characterized by partial facial paralysis) is not associated with improved recovery of facial movement function, according to a meta-analysis of previously published studies in the June issue of Archives of Otolaryngology-Head & Neck Surgery.

16 Jun 2009

FDA releases fraudulent H1N1 flu virus product list

The U.S. Food and Drug Administration is enforcing the laws that protect consumers from illegal products marketed through the Internet that claim to diagnose, prevent, mitigate, treat or cure the 2009 H1N1 flu virus.

15 Jun 2009

Research identifies 3D structure of key nuclear pore building block

The genome of complex organisms is stashed away inside each cell's nucleus, a little like a sovereign shielded from the threatening world outside.

8 Jun 2009

Discovery of new arenavirus associated with hemorrhagic fever – first identified in nearly four decades

Scientists at Columbia University's Mailman School of Public Health, the South African National Institute for Communicable Diseases of National Health Laboratory Service (NICD-NHLS), the U.S. Centers for Disease Control and Prevention, and Roche's 454 Life Sciences Corporation have discovered the new virus responsible for a highly fatal hemorrhagic fever outbreak in Zambia and South Africa in late 2008.

2 Jun 2009

Discovery of biochemical signals that help immune cells remember how to fight infection

Immunology researchers at UT Southwestern Medical Center have discovered how two biochemical signals play unique roles in promoting the development of a group of immune cells employed as tactical assassins.

28 May 2009

Chronic infection clearly linked to key immunity protein

The reason deadly infections like human immunodeficiency virus (HIV) and hepatitis C never go away is because these viruses disarm the body's defense system.

15 May 2009

Cytomegalovirus may cause high blood pressure

A new study suggests for the first time that cytomegalovirus (CMV), a common viral infection affecting between 60 and 99 percent of adults worldwide, is a cause of high blood pressure, a leading risk factor for heart disease, stroke and kidney disease.

15 May 2009

New insights into immune exhaustion

A main reason why viruses such as HIV or hepatitis C persist despite a vigorous initial immune response is exhaustion. The T cells, or white blood cells, fighting a chronic infection eventually wear out.

13 May 2009

New mathematical model predicts immune response to influenza A virus

Researchers at the University of Rochester have developed a mathematical model to predict immune responses to infection with influenza A viruses, including novel viruses such as the emergent 2009 influenza A (H1N1). This model examines the contributions of specific sets of immune cells in fighting influenza A virus.

13 May 2009

A potentially better way to make flu virus vaccines

A team of Princeton University scientists may have found a better way to make a vaccine against the flu virus.

12 May 2009

FDA approves Creon (pancrelipase) - designed to help those with cystic fibrosis

The U.S. Food and Drug Administration announced that it has approved Creon (pancrelipase), a pancreatic enzyme replacement product designed to help patients with cystic fibrosis and others with exocrine pancreatic insufficiency (EPI) digest and absorb nutrients from foods.

7 May 2009