Viral Vector News and Research

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Viral Vector is a type of virus used in cancer therapy. The virus is changed in the laboratory and cannot cause disease. Viral vectors may produce tumor antigens (proteins found on a tumor cell) to stimulate an antitumor immune response in the body. Viral vectors may also be used to carry genes that can change cancer cells back to normal cells.

Gene therapy study shows promise for chronic kidney disease

A study has shown that a viral vector can deliver genetic material to damaged kidney cells, potentially providing a treatment that can slow or reverse chronic kidney disease.

6 Jul 2018

Mice study shows beneficial effect of MANF treatment on reversal of stroke-induced behavioral deficits

Stroke is the most common cause of adult disability. This is due not only to the high incidence of stroke, but also because spontaneous recovery is often incomplete and no drugs are available that hasten recovery.

11 Jun 2018

Sartorius Stedim Biotech selected by ABL Europe to supply single-use process technologies

Sartorius Stedim Biotech S.A., a leading international technology partner of the biopharmaceutical industry, has been selected by ABL Europe as its primary supplier of single-use systems.

From Sartorius 21 Mar 2018

Innovative antibody delivery method could offer effective way to combat Ebola infection

More than 11,000 people died during the Ebola outbreak in West Africa from 2013-16, demonstrating both the deadly nature of the virus and the limitations of the medication used to fight it.

6 Mar 2018

Treatments targeted to enhance brain neurotrophic factor signaling may improve memory functions

Treatments targeted to enhance brain neurotrophic factor signaling could improve memory functions in Alzheimer's disease even though they don't alter brain amyloid burden, according to recent research from the University of Eastern Finland.

6 Mar 2018

Researchers develop gene therapy that treats a form of macular degeneration in canine model

Researchers from the University of Pennsylvania have developed a gene therapy that successfully treats a form of macular degeneration in a canine model.

6 Mar 2018

Experimental therapy may enhance recovery for stroke patients

An experimental therapy being tested by University of Alberta scientists that targets the spinal cord may one day be key to spurring on enhanced recovery for stroke victims.

1 Feb 2018

Researchers describe severe toxicity with AAV9-based high-dose gene therapy in animal models

Researchers have described severe, life-threatening toxicity in monkeys and piglets given high doses of gene therapy delivered using an adeno-associated virus (AAV9) vector capable of accessing spinal cord neurons.

30 Jan 2018

The Salk Institute and Indivumed collaborate for cutting-edge cancer research

The Salk Institute, which hosts a National Cancer Institute-designated cancer center and Indivumed GmbH, a world leading cancer research company today announce a multi-year strategic alliance to secure, preserve and analyze human cancer tissue and annotated clinical data from consenting patients around the world, enabling the most cutting-edge basic and translational research in cancer.

16 Jan 2018

New, more easily administered therapies offer benefits for bleeding and clotting disorders

In three studies being presented today during the 59th American Society of Hematology (ASH) Annual Meeting and Exposition in Atlanta, researchers report remarkable benefits from new, more easily administered therapies for bleeding and clotting disorders.

11 Dec 2017

Gene therapy shows promising effect against blood clots, study states

A new study conducted in the Children's Hospital Of Philadelphia (CHOP) reported positive results in a phase 1/2 clinical trial for the inherited bleeding disorder hemophilia B.

8 Dec 2017

Gene therapy prevents age-related learning and memory problems in mice

Researchers from the Institute of Neurosciences at the Universitat Autònoma de Barcelona and the Vall d'Hebron Research Institute are the first to demonstrate that regulation of the brain's Klotho gene using gene therapy protects against age-related learning and memory problems in mice.

31 Oct 2017

Gene therapy effectively stabilizes progression of cerebral adrenoleukodystrophy, trial reveals

In a recent clinical trial, a gene therapy to treat cerebral adrenoleukodystrophy (CALD) -- a neurodegenerative disease that typically claims young boys' lives within 10 years of diagnosis -- effectively stabilized the disease's progression in 88 percent of patients, researchers from the Dana-Farber/Boston Children's Cancer and Blood Disorders Center and Massachusetts General Hospital report today.

4 Oct 2017

New version of gene editing technique corrects molecular mistakes in RNA-based diseases

Until recently, the CRISPR-Cas9 gene editing technique could only be used to manipulate DNA. In a 2016 study, University of California San Diego School of Medicine researchers repurposed the technique to track RNA in live cells in a method called RNA-targeting Cas9 (RCas9).

11 Aug 2017

Preclinical study demonstrates efficacy of gene therapy in treatment of Duchenne muscular dystrophy

Researchers from Genethon, the AFM-Telethon laboratory, Inserm (UMR 1089, Nantes) and the University of London (Royal Holloway) demonstrated the efficacy of an innovative gene therapy in the treatment of Duchenne muscular dystrophy.

25 Jul 2017

Cord-blood-derived natural killer cells can be modified to destroy B-cell cancers

Immune cells with a general knack for recognizing and killing many types of infected or abnormal cells also can be engineered to hunt down cells with specific targets on them to treat cancer, researchers at The University of Texas MD Anderson Cancer Center report in the journal Leukemia.

13 Jul 2017

Research shows new Zika virus vaccine that offers 100% protection in mice

Research presented by Farshad Guirakhoo, Ph.D., Chief Scientific Officer, GeoVax, Inc., at the ASM Microbe 2017 meeting showed a new Zika virus vaccine that gives 100% protection in mice.

5 Jun 2017

Spanish scientists develop promising gene therapy method to treat Wilson's disease

Scientists at the Center for Applied Medical Research at the University of Navarra have designed a promising gene therapy method to treat Wilson's disease, a rare pathology caused by the lack of or malfunction of a gene.

16 May 2017

Sangamo Therapeutics and Pfizer team up for development of Hemophilia A gene therapy

Sangamo Therapeutics, Inc. and Pfizer Inc. today announced an exclusive, global collaboration and license agreement for the development and commercialization of gene therapy programs for Hemophilia A, including SB-525, one of Sangamo's four lead product candidates, which Sangamo expects will enter the clinic this quarter.

11 May 2017

Novel approach cures diabetes in mice for one year without side effects

A potential cure for Type 1 diabetes looms on the horizon in San Antonio, and the novel approach would also allow Type 2 diabetics to stop insulin shots.

5 May 2017

Viral Vector News and Research

Further Reading

Gene therapy study shows promise for chronic kidney disease

Mice study shows beneficial effect of MANF treatment on reversal of stroke-induced behavioral deficits

Sartorius Stedim Biotech selected by ABL Europe to supply single-use process technologies

Innovative antibody delivery method could offer effective way to combat Ebola infection

Treatments targeted to enhance brain neurotrophic factor signaling may improve memory functions

Researchers develop gene therapy that treats a form of macular degeneration in canine model

Experimental therapy may enhance recovery for stroke patients

Researchers describe severe toxicity with AAV9-based high-dose gene therapy in animal models

The Salk Institute and Indivumed collaborate for cutting-edge cancer research

New, more easily administered therapies offer benefits for bleeding and clotting disorders

Gene therapy shows promising effect against blood clots, study states

Gene therapy prevents age-related learning and memory problems in mice

Gene therapy effectively stabilizes progression of cerebral adrenoleukodystrophy, trial reveals

New version of gene editing technique corrects molecular mistakes in RNA-based diseases

Preclinical study demonstrates efficacy of gene therapy in treatment of Duchenne muscular dystrophy

Cord-blood-derived natural killer cells can be modified to destroy B-cell cancers

Research shows new Zika virus vaccine that offers 100% protection in mice

Spanish scientists develop promising gene therapy method to treat Wilson's disease

Sangamo Therapeutics and Pfizer team up for development of Hemophilia A gene therapy

Novel approach cures diabetes in mice for one year without side effects

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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