Vision Loss News and Research

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Lux initiates pivotal voclosporin Phase 3 trial in non-infectious uveitis

Isotechnika Pharma Inc. announced today that Lux Biosciences, Inc. has commenced its pivotal Phase 3 trial using voclosporin for the treatment of non-infectious uveitis, a leading cause of vision loss and long-term disability.

25 Feb 2011

Early diagnosis can delay or halt progression of macular degeneration

February is Age-related Macular Degeneration and Low Vision Awareness month, providing an opportunity to inform and educate the public on the leading cause of vision loss for adults over the age of 65. Today, over 15 million of these adults suffer from age-related macular degeneration, a number that is expected to grow considerably as the baby boomer generation begins heading into retirement age. While the risks are growing, awareness and education is key to treating and saving the eyesight of millions.

19 Feb 2011

Canadian Cancer Society praises new, enhanced cigarette package warnings

Today, Health Canada released a set of new picture health warnings for cigarette and little cigar packages. The new labels include 16 warnings that will cover 75 per cent of the package front and back, eight additional messages to be printed inside the package (or on an insert), and four toxic emission messages for the side panel.

19 Feb 2011

Phase III RISE study of Lucentis for DME meets primary endpoint

Genentech, Inc., a member of the Roche Group, announced today that one of two Phase III studies evaluating monthly Lucentis® (ranibizumab injection) in patients with diabetic macular edema (DME), met its primary endpoint. DME is a serious complication of diabetes that affects up to 10 percent of people with the disease and can lead to blurred vision, severe vision loss and blindness.

14 Feb 2011

Study explores levels of burden and depression in caregivers with sensory impairment

When a person experiences impairment or declining health, caregiving typically falls to a family member, most often a spouse. This increased burden can cause burnout, stress, and illness in the caregiver. The health care system focuses first on the client and provides little support for the caregiver.

14 Feb 2011

Doctors of Optometry troubled by disregard for vision and eye health needs of children

The American Optometric Association, the voice of America's family eye doctors, today warned that if a set of U.S. Preventive Services Task Force recommendations are adopted as policy, significant harm will be caused to the ongoing efforts of eye doctors nationwide to reverse the high rates of preventable vision loss in children across America, from the first year of life through age 5.

5 Feb 2011

Both absence of insulin and resistance to insulin are associated with defects in FAS

A key mechanism that appears to contribute to blood vessel damage in people with diabetes has been identified by researchers at Washington University School of Medicine in St. Louis.

28 Jan 2011

Regeneron, Bayer and SERI initiate new VEGF Trap-Eye Phase 3 clinical trial in myopic CNV

Regeneron and Bayer HealthCare announced initiation of a new Phase 3 clinical trial in collaboration with the Singapore Eye Research Institute investigating the efficacy and safety of VEGF Trap-Eye (aflibercept ophthalmic solution) in patients with choroidal neovascularisation (CNV) of the retina as a result of pathologic myopia.

18 Jan 2011

Study supports use of PRX as an anti-cataract agent

Scientists are reporting a scientific basis for the long-standing belief that a widely used non-prescription drug in China and certain other countries can prevent and treat cataracts, a clouding of the lens of the eye that is a leading cause of vision loss worldwide. Their study appears in Inorganic Chemistry, an ACS journal.

13 Jan 2011

Nutriceuticals may restore age-related vision loss

While age-related vision loss of catastrophic proportions is predicted in coming decades, rising from 17 million patients today to 55 million by the year 2050, it's possible this catastrophe could be averted and lost vision even restored using molecular medicine.

11 Jan 2011

Alkeus and Columbia University enter license agreement for potential therapies for dry-AMD, Stargardt disease

Alkeus Pharmaceuticals and Columbia University announced today that they have entered into a license agreement for a set of potential therapies for the treatment of dry age-related macular degeneration (dry-AMD), Stargardt disease, and other degenerative diseases of the eye. Left untreated, these conditions often lead to impaired vision and even blindness.

5 Jan 2011

Get examined during Glaucoma Awareness Month

It happens slowly. Over time, a person's vision will get worse. Until one day, that person can no longer see. Glaucoma is the second leading cause of blindness in the United States and worldwide. Unfortunately, there is no cure. Once a person's vision is lost, it cannot be regained. That is why Dr. Bizer's VisionWorld is encouraging people to get an examination during Glaucoma Awareness Month.

5 Jan 2011

Researchers identify new biological pathway that contribute to glaucoma

In a study published today in the Proceedings of the National Academy of Sciences, a team of researchers from the Kennedy Krieger Institute and four collaborating institutions, identified a new and unexpected biological pathway that appears to contribute to the development of glaucoma and its resulting vision loss.

4 Jan 2011

FDA clears ACT's IND to treat AMD using hESC derived RPE cells

Advanced Cell Technology, Inc., a leader in the field of regenerative medicine, announced today that the US Food and Drug Administration (FDA) has cleared the Company's Investigational New Drug (IND) application to treat Dry Age-Related Macular Degeneration (AMD) using retinal pigment epithelial (RPE) cells derived from human embryonic stem cells (hESCs).

3 Jan 2011

NEI awards Case Western Reserve $10M for study of retinal diseases

The Departments of Pharmacology and Ophthalmology and Visual Sciences at Case Western Reserve University School of Medicine have been awarded a $10.1 million grant from the National Eye Institute (NEI) to research and develop new treatments for diseases of the retina, a leading cause of blindness.

29 Dec 2010

FDA recommends removal of breast cancer indication from Avastin label

The U.S. Food and Drug Administration announced today that the agency is recommending removing the breast cancer indication from the label for Avastin (bevacizumab) because the drug has not been shown to be safe and effective for that use.

17 Dec 2010

Closer to restoring vision loss due to optic nerve damage

Damage to the optic nerve, connecting the eye with the brain, is a major cause of blindness. The most common culprit is glaucoma, estimated to affect more than 4 million Americans. There is currently no way to restore the lost vision, because the optic nerve, like other nerves in the mature central nervous system (CNS), cannot regenerate. Now, scientists at Children's Hospital Boston report achieving the greatest regeneration to date in the mammalian optic nerve.

4 Dec 2010

Vision problems in stroke patients can impact rehabilitation

Visual problems can affect up to two thirds of stroke patients, but can sometimes go undetected if patients do not recognise them as an after-effect of the condition or if they are unable to communicate the problem to their medical team or families.

2 Dec 2010

Early eye exam can save sight and prevent a life time disability

Jennifer Hartman had no idea her child had a significant vision problem. The day after her daughter's sixth birthday, after an eye exam, she was diagnosed as being legally blind in one eye with a condition called amblyopia or lazy eye.

1 Dec 2010

FDA grants ACT clearance for Phase I/II clinical trial of hESC derived retinal cells in patients with SMD

Advanced Cell Technology, Inc. announced today that the US Food and Drug Administration (FDA) has cleared the Company's Investigational New Drug (IND) application to immediately initiate a Phase I/II multicenter clinical trial using retinal cells derived from human embryonic stem cells (hESCs) to treat patients with Stargardt's Macular Dystrophy (SMD), one of the most common forms of juvenile macular degeneration in the world. The decision removes the clinical hold that the FDA had placed on the trial.

22 Nov 2010