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Study establishes link between Piezo1 and intracellular cholesterol levels during neural development

A new University of California, Irvine-led study reveals how mechanical forces and tissue mechanics influence the morphology of the developing brain, and establishes a direct link in neural stem cells between Piezo1, a mechanically-activated ion channel, and intracellular cholesterol levels during neural development.

8 Sep 2022

Administering immunotherapy drug before surgery for oral cavity cancer did not increase complications

A University of Cincinnati study found administering an immunotherapy drug before surgery for oral cavity cancer did not lead to increased rates of complications during and after surgery.

7 Sep 2022

Single-cell Stereo-seq reveals new insights into axolotl brain regeneration

The axolotl Ambystoma mexicanum is a popular pet due to its unique and cute appearance. Unlike other salamanders undergoing metamorphosis, axolotls (pronounced ACK-suh-LAH-tuhl) never outgrow their larval, juvenile stage, a phenomenon called neoteny.

6 Sep 2022

Research shows how orderly regeneration is activated after injury

The phenomenon of regeneration was discovered over 200 years ago in the freshwater polyp Hydra. Until now, however, it was largely unclear how the orderly regeneration of lost tissues or organs is activated after injury.

2 Sep 2022

3 shots in 1: How microparticles could be used to deliver self-boosting vaccines

In this interview, we speak to Morteza Sarmadi from MIT about his labs latest research that developed microparticles able to deliver self-boosting vaccines.

30 Aug 2022

Inactivation of particular protein complex associated with Parkinson's and anxiety disorders

Inactivation of a particular protein complex that plays a key role in keeping genes switched off leads to nerve cells not producing enough essential neurotransmitters.

29 Aug 2022

High-throughput proteomics reveals pregnancy-specific responses to COVID-19

Researchers evaluated pregnancy-specific responses to SARS-CoV-2 infection.

29 Aug 2022

Study shows how Klebsiella pneumoniae suppresses the body's defenses

New research published in Cell Reports has shown how the bacterium Klebsiella pneumoniae suppresses our body's defences, resulting in it being unable to clear infection.

24 Aug 2022

Researchers discover the vital role of immune cells in liver regeneration

If liver tissue has to be removed due to cancer or another liver disease, the organ usually regenerates quickly, soon becoming fully functional once again.

24 Aug 2022

Cornea implant made of collagen from pig’s skin restores vision

In this interview, News-Medical speaks to Professors Neil Lagali and Mehrdad Rafat about their latest research, which detailed a bioengineered corneal tissue for minimally invasive vision restoration in advanced keratoconus in two clinical cohorts.

23 Aug 2022

They call it ‘tranq’ — and it’s making street drugs even more dangerous

Approaching a van that distributes supplies for safer drug use in Greenfield, Massachusetts, a man named Kyle noticed an alert about xylazine.

11 Aug 2022

Study shows how the same protein that is key for brain development can also be the cause for the spread of cancer

Researchers at Queen's University Belfast have revealed how the pathway of an identified protein could lead to early diagnosis and targeted treatment for several cancers and brain disorders.

10 Aug 2022

Aberrant levels of three microRNAs may impair healing in venous ulcers, study shows

The study, which includes the first resource detailing the role of microRNAs in the wound-repair process, shows that aberrant levels of a trio of microRNAs may impair healing in venous ulcers.

9 Aug 2022

Vitamin A supplementation is missed by two in five children in India, analysis finds

Two in five eligible children in India are missing out on preventive vitamin A supplementation designed to ward off the health problems associated with deficiency of the vitamin, finds an analysis of representative survey data, published in the open access journal BMJ Global Health.

29 Jul 2022

Hospices have become big business for private equity firms, raising concerns about end-of-life care

Hospice care, once provided primarily by nonprofit agencies, has seen a remarkable shift over the past decade, with more than two-thirds of hospices nationwide now operating as for-profit entities.

29 Jul 2022

New technology converts discarded bullfrog skin into wound healing products

A new clinical-grade collagen made from discarded bullfrog skin is leapfrogging from the lab bench to clinics soon.

27 Jul 2022

New treatment guidelines published for anorectal abscess, anal fistula, and rectovaginal fistula

The American Society of Colon and Rectal Surgeons has issued updated guidelines for physicians, published in Diseases of the Colon & Rectum, about how to treat problems of the anus and rectum called anorectal abscess, anal fistula, and rectovaginal fistula.

22 Jul 2022

Tissue nanotransfection technology can serve as a non-viral, topical, gene-editing delivery device, research shows

The Indiana Center for Regenerative Medicine and Engineering (ICRME) at Indiana University School of Medicine is home to tissue nanotransfection (TNT) regenerative medicine technology that achieves functional tissue reprogramming in the live body.

19 Jul 2022

Chemokine-DNA nanoparticles can induce chronic, dysfunctional immune responses

Small proteins, called chemokines, that direct immune cells toward sites of infection can also form DNA-bound nanoparticles that can induce chronic, dysfunctional immune responses, according to a new study by researchers at Weill Cornell Medicine and Hospital for Special Surgery (HSS).

15 Jul 2022

Nurse midwives step up to provide prenatal care after two rural hospitals shutter birthing centers

Bailee Tordai, who was 33 weeks into her pregnancy, barely made it to the prenatal checkup. Her clunky old Jeep couldn't complete the 2-mile trip from her house to the University of Iowa's outreach clinic in her southeastern Iowa hometown.