Wound Healing News and Research

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Natural killer cells mediate a trade-off between wound healing and bacterial defense

Natural killer cells do not just kill cancer cells or cells infected with viruses, they also mediate a trade-off between wound healing and bacterial defense in skin wounds.

8 Sep 2021

Researchers develop new drug-free treatment to accelerate healing of chronic diabetic wounds

About one-fourth of people with diabetes develop painful foot ulcers, which are slow to heal due to low oxygen in the wound from impaired blood vessels and increased inflammation. These wounds can become chronic, leading to poor quality of life and potential amputation.

31 Aug 2021

The impact of mild SARS-CoV-2 infection on maternal-fetal immunity

Recently, a new study published on the pre-print server bioRxiv* examined the effect that maternal asymptomatic COVID-19 had on decidual and peripheral immune cells during the later stage of pregnancy.

30 Aug 2021

Combination therapy disables PI3K/Akt/mTOR pathway and induces apoptosis in carcinoid syndrome

Oncotarget published "Next-generation multimodality of nutrigenomic cancer therapy: sulforaphane in combination with acetazolamide actively target bronchial carcinoid cancer in disabling the PI3K/Akt/mTOR survival pathway and inducing apoptosis" which reported that microscopic imaging, immunocytochemistry, wound healing assay, caspase-cleaved cytokeratin 18 CytoDeath ELISA assay, immunofluorescence labeling assays for apoptosis, hypoxia, Western Blotting, Tunnel assay, measurement of 5-HT secretion by carbon fiber amperometry assay, quantitative methylation-specific PCR, morphologic changes, cell viability, apoptosis activity and the expression levels of phospho-Akt1, Akt1, HIF-1α, PI3K, p21, CAIX, 5-HT, phospho-mTOR, and mTOR in xenografts derived from typical H727 and atypical H720 BC cell lines.

28 Aug 2021

Fetal membranes can heal after injury, study shows

Scientists from Queen Mary University of London and UCL have shown that fetal membranes are able to heal after injury in a new study.

18 Aug 2021

Analysis of landmark vitamin C study challenges the WHO's recommended daily amounts

It was wartime and food was scarce. Leaders of England's effort to wage war and help the public survive during World War II needed to know: Were the rations in lifeboats adequate for survival at sea? And, among several experiments important for public as well as military heath, how much vitamin C did a person need to avoid the deadly disease scurvy?

16 Aug 2021

Tiny gel drops for the development of regenerative therapies

Tiny drops that resemble an extracellular matrix can be used to culture cells for delivery into the human body.

9 Aug 2021

Light therapy may speed up the healing of burns by activating growth protein

Light therapy may accelerate the healing of burns, according to a University at Buffalo-led study.

6 Aug 2021

New molecular and morphologic insights into chronic rejection after lung transplantation

A study of lung tissue from patients with end-stage bronchiolitis obliterans syndrome (BOS) as a complication of lung transplantation yielded molecular and morphologic insights into the development of chronic rejection.

3 Aug 2021

Researchers propose new scoring system for assessing wound healing dynamics

Evaluating the efficacy of novel therapies requires the ability to monitor wound progression accurately and reproducibly over time.

21 Jul 2021

Protein involved in cell migration offers clues to cancer metastases

A protein involved in making cells move offers a clue to how certain types of cancer metastasize and develop into secondary tumors, according to new research from the University of Warwick.

21 Jul 2021

Research reveals clues to how a molecule improves appearance of surgery scars

Surgical scars treated with a molecule called alphaCT1 showed a long-term improvement in appearance when compared to control scars, according to multicenter, controlled Phase II clinical trials - a finding that could help surgeons improve patient outcomes.

20 Jul 2021

Targeting Piezo1 protein may be a new and ideal strategy to cure multiple sclerosis

In a new University of California, Irvine-led study, researchers found that a certain protein prevented regulatory T cells (Tregs) from effectively doing their job in controlling the damaging effects of inflammation in a model of multiple sclerosis (MS), a devastating autoimmune disease of the nervous system.

20 Jul 2021

MCG scientists find copper transporter as potential therapeutic target for cardiovascular diseases

An internal transporter that enables us to use the copper we consume in foods like shellfish and nuts to enable a host of vital body functions also has the essential role of protecting the receptor that enables us to grow new blood vessels when ours become diseased, Medical College of Georgia scientists report.

20 Jul 2021

Novel cold-tolerant bacterium produces a red bio-pigment with germ-killing properties

A team of researchers from Shoolini University, Himachal Pradesh, India have discovered a psychrophilic bacterial strain, called Rhodonellum psychrophilum GL8, at the high altitude Pangong Tso Lake in the Himalayas.

12 Jul 2021

Findings suggest that the cross-linking of fibrin proteins is key to reducing blood clot formation

Researchers have found that the y cross-chain structure of fibrin proteins is essential to stabilizing blood clots that can lead to harmful embolism formation.

29 Jun 2021

Researchers develop smart wound dressings with built-in healing sensors

Researchers have developed smart wound dressings with built-in nanosensors that glow to alert patients when a wound is not healing properly.

28 Jun 2021

Plasma zinc status not an effective prognostic factor for hospitalized COVID-19 patients

Due to previous evidence suggesting that zinc deficiencies can lead to complications along with an impaired antiviral response, a group of international researchers has undertaken a prospective observational study to investigate this association further.

14 Jun 2021

New wound gap closure mechanism may offer faster, better healing after injury or surgery

The observation of a previously undetected biological mechanism for closing gaps in living tissue improves basic understanding of the wound-healing process and may one day inform strategies to speed healing after surgery, according to a team of Penn State and Singapore researchers.

14 Jun 2021

Hair follicle stem cells play an outsize role in healing skin blisters

A team of scientists has shown that the healing of skin blisters is driven by hair follicle stem cells, which delay their own development in the process.

14 Jun 2021

Wound Healing News and Research

Natural killer cells mediate a trade-off between wound healing and bacterial defense

Researchers develop new drug-free treatment to accelerate healing of chronic diabetic wounds

The impact of mild SARS-CoV-2 infection on maternal-fetal immunity

Combination therapy disables PI3K/Akt/mTOR pathway and induces apoptosis in carcinoid syndrome

Fetal membranes can heal after injury, study shows

Analysis of landmark vitamin C study challenges the WHO's recommended daily amounts

Tiny gel drops for the development of regenerative therapies

Light therapy may speed up the healing of burns by activating growth protein

New molecular and morphologic insights into chronic rejection after lung transplantation

Researchers propose new scoring system for assessing wound healing dynamics

Protein involved in cell migration offers clues to cancer metastases

Research reveals clues to how a molecule improves appearance of surgery scars

Targeting Piezo1 protein may be a new and ideal strategy to cure multiple sclerosis

MCG scientists find copper transporter as potential therapeutic target for cardiovascular diseases

Novel cold-tolerant bacterium produces a red bio-pigment with germ-killing properties

Findings suggest that the cross-linking of fibrin proteins is key to reducing blood clot formation

Researchers develop smart wound dressings with built-in healing sensors

Plasma zinc status not an effective prognostic factor for hospitalized COVID-19 patients

New wound gap closure mechanism may offer faster, better healing after injury or surgery

Hair follicle stem cells play an outsize role in healing skin blisters

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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