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Improved-resolution views of a zinc transporter protein deciphered

New, improved-resolution views of a zinc transporter protein deciphered at the U.S. Department of Energy's Brookhaven National Laboratory provide not just a structure but also a suggested mechanism for how cells sense and regulate zinc, an element that is essential for life, but which must be kept at a steady state to avoid problems like seizures, diabetes, and possibly Alzheimer's disease.

14 Sep 2009

Acceleron's Phase 1 trial of ACE-031 reveals its potential in treating neuromuscular diseases

Acceleron Pharma, Inc., a biopharmaceutical company developing novel therapeutics that modulate the growth of cells and tissues including red blood cells, bone, and muscle, today announced preliminary results from the ACE-031 Phase 1 single dose clinical trial demonstrating that ACE-031 increased lean body mass and muscle volume. The results from this randomized, placebo-controlled study were presented at the 14th International Congress of the World Muscle Society in Geneva, Switzerland.

10 Sep 2009

Brain's SCN is the master clock that synchronizes other biological clocks in the body

Alexis Webb enters a small room at Washington University in St. Louis with walls, floor and ceiling painted dark green, shuts the door, turns off the lights and bends over a microscope in a black box draped with black cloth. Through the microscope, she can see a single nerve cell on a glass cover slip glowing dimly.

10 Sep 2009

Lead exposure may result in cardiovascular mortality

Growing evidence shows that exposure to lead in the environment is associated with cardiovascular disease, including increased risk of hypertension. However, those studies have looked at lead concentrations in blood, not bone lead, a better indicator of cumulative lead exposure over time.

10 Sep 2009

Synexus on track to double its clinical trial capacity in South Africa, opens two new research centres in Pretoria

Manchester-based Synexus, the world’s largest multi-national company dedicated to the recruitment and running of clinical trials, celebrated the first phase of its South African expansion programme in Pretoria today.

From AES - Accelerated Enrollment Solutions 9 Sep 2009

FDA approves the distribution of IMRISNV and IMRIScardio systems

IMRIS Inc. ("IMRIS" or the "Company") today announced that it has received 510(k) clearance from the US Food and Drug Administration (FDA), permitting the Company to market its newest products, IMRISNV and IMRIScardio in the United States.

9 Sep 2009

Campaign seeks to distribute 700m bednets in sub-Saharan Africa by 2015

Several organization led by the WHO have contributed $5 billion for a campaign aimed at distributing 700 million bednets to prevent malaria in sub-Saharan Africa by 2015, the East African reports.

9 Sep 2009

Western Dental Services launches digital X-ray imaging program

CDW Healthcare, part of the public sector subsidiary of CDW Corporation and a leading provider of technology products and services to healthcare organizations, today announced that Western Dental Services, Inc. (“Western Dental”) of Orange, Calif., launched an extensive digital X-ray imaging program powered via technology configured and deployed by CDW Healthcare.

8 Sep 2009

BEST bags orders for state-of-the-art synchrotron instrumentation

Bruker Energy & Supercon Technologies, Inc. (BEST) today announced that its subsidiary Bruker ASC GmbH in Bergisch Gladbach, Germany, has been awarded several significant contracts for state-of-the-art synchrotron instrumentation from leading research institutions worldwide.

8 Sep 2009

NSF grants funds to develop next-generation nano-CT imaging system

In 1991, Ge Wang produced the first paper on spiral cone-beam computed tomography (CT), now an imaging technique used in the mainstream of the medical CT field. Today, Wang, known as a pioneer in this field, and his colleagues have been awarded more than $1.3 million from the National Science Foundation (NSF) to develop the next-generation nano-CT imaging system, which promises to greatly reduce the required dose of radiation.

4 Sep 2009

Insects may guide in building better artificial tissues and organs

Insects are about to be analyzed in a new way by a host of Virginia Tech engineering faculty. They will be using some fancy state-of-the-art equipment, such as a kilometer-long synchrotron x-ray light source, which might be enough to scare any bug. And first up will be beetles, grasshoppers and silk moths because they have some endearing characteristics.

4 Sep 2009

Banner Good Samaritan treats cancers and neurological disorders with the Novalis Tx radiosurgery platform

John J. Kresl, M.D., Ph.D., and colleagues at Banner Good Samaritan Medical Center are now treating a wide variety of cancers and neurological disorders with highly-accurate, non-invasive, image-guided radiosurgery using the Novalis Tx(TM) radiosurgery platform from Varian Medical Systems (NYSE: VAR) and BrainLAB.

4 Sep 2009

MPI Research appoints Executive Vice President of Sales and Marketing

MPI Research announced today that Thomas Laughlin will join the company as Executive Vice President of Sales and Marketing and will be a member of the company’s Corporate Management Team. Laughlin’s 30+ years of executive experience span several of the world’s largest and most successful healthcare products companies.

3 Sep 2009

Study reports a potential new investigational therapy for skin cancer

A study published today in the New England Journal of Medicine reports a potential new investigational therapy for advanced and metastatic basal cell skin cancer tested at the Virginia G. Piper Cancer Center at Scottsdale Healthcare and other sites appears to demonstrate tumor shrinkage and limited side effects in patients.

3 Sep 2009

SPi acquires Laguna Medical Systems for $8.25 million

SPi, a leading global business process outsourcing (BPO) company, today announced that it has acquired Laguna Medical Systems, Inc. (LMS) for an aggregate purchase price of US $8.25 million.

3 Sep 2009

Boron-based molecules can be used as new pharmacophores

Chemists and biologists have successfully demonstrated that specially synthesized boron compounds are readily accepted in biologically active enzymes, a move that, they say, is a proof of concept that could lead to new drug design strategies.

3 Sep 2009

New therapy for advanced and metastatic basal cell skin cancer

3 Sep 2009

The CyberKnife Robotic Radiosurgery System deployed at the CHUM

In operation since recently at the Centre hospitalier de l'Université de Montréal (CHUM), the CyberKnife(R) Robotic Radiosurgery System, is revolutionizing the treatment of both cancerous and non-cancerous tumors anywhere in the body. Used in radiation oncology, the CyberKnife System is the latest word in radiosurgery technology. Designed to destroy tumours using radiation beams, it is the first system of its kind to treat tumors non-invasively to be installed in Canada.

2 Sep 2009

Hope for limiting skin toxicity of cancer drug users

There may be a way around the harsh skin toxicity associated with a widely used cancer drug, according to a study published online this week in Cancer Biology and Therapy by researchers from City of Hope and the Kimmel Cancer at Jefferson.

2 Sep 2009

St. Luke's Episcopal Hospital uses CyberKnife robotic radiosurgery system for treating tumours

St. Luke's Episcopal Hospital is the first hospital in Houston to feature the CyberKnife((R)), a noninvasive alternative to surgery for the treatment of both cancerous and non-cancerous tumors.

2 Sep 2009