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New approach to predict protein function

In a paper published online this month in the journal Nature Chemical Biology, researchers report that they have developed a way to determine the function of some of the hundreds of thousands of proteins for which amino acid sequence data are available, but whose structure and function remain unknown.

12 Jul 2007

Brain lesions may be sign of more widespread disease in the brain

Lesions commonly seen on MRI in the brains of older patients may be a sign of potentially more extensive injury to the brain tissue, according to a recent study conducted by researchers at the Duke University Medical Center, in Durham, NC.

10 Jul 2007

New weapon in the battle against antibiotic-resistant bacteria

Putting bacteria on birth control could stop the spread of drug-resistant microbes, and researchers at the University of North Carolina at Chapel Hill have found a way to do just that.

10 Jul 2007

Waiting for joint replacement surgery

A team of Bristol University researchers are aiming to find out why some people waiting for a hip or knee replacement have to wait longer than others for surgery.

9 Jul 2007

Researchers discover why some mosquitoes are resistant to malaria

A team led by UT Southwestern Medical Center researchers has discovered why some mosquitoes are resistant to malaria, a finding that may one day help fight a disease that afflicts and kills millions of people.

9 Jul 2007

Orlistat weight loss drug points to new cancer treatments

Based on their surprising discovery that an obesity drug can kill cancer cells, scientists at Wake Forest University School of Medicine have made a new finding about the drug's effects and are working to design more potent cancer treatments.

9 Jul 2007

Multiple-electrode radiofrequency ablation safe and effective way of treating patients with liver cancer

Multiple-electrode radiofrequency ablation is a safe and effective way of treating patients with liver cancer that can be completed in less time than current ablation techniques, according to a recent study conducted by researchers at the University of Wisconsin in Madison.

29 Jun 2007

Scientists create sheets of protein-gold arrays

In groundbreaking research, scientists have demonstrated the ability to strategically attach gold nanoparticles -- particles on the order of billionths of a meter -- to proteins so as to form sheets of protein-gold arrays.

28 Jun 2007

Decline in mental health after SARS

Most patients who survived severe acute respiratory syndrome (SARS) had good physical recovery, but they or their caregivers often reported a decline in mental health one year later, according to a study in the June 25 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

26 Jun 2007

New compound kills fungal pathogens

A new mechanism to attack hard-to-treat fungal infections has been revealed by scientists from the biotech company Anacor Pharmaceuticals Inc., California, and the European Molecular Biology Laboratory (EMBL) outstation in Grenoble, France.

23 Jun 2007

New cancer drug target

Research led by scientists at Weill Cornell Medical College has uncovered two new potential points of vulnerability on a key cancer-promoting protein, called XIAP.

23 Jun 2007

Anacor finds novel mechanism for lead anti-fungal drug, AN2690

Anacor Pharmaceuticals, a privately held pharmaceutical company, has announced that the journal Science will publish results of research that details how AN2690, the company's lead clinical candidate, kills fungal cells by interfering with synthesis of a specific protein required for fungal growth.

23 Jun 2007

Standards for the use of ultrasound to measure narrowing of the carotid artery may be too aggressive

These standards, used by the majority of vascular laboratories around the country since the early 1980s, were based on the use of angiography, a medical imaging technique in which an X-ray picture is taken to visualize the inner opening of blood filled structures.

8 Jun 2007

Researchers develop criteria to detect bone mass deficiencies in children with chronic diseases

Pediatricians now have a practical tool to help determine whether children with chronic diseases like Crohn's, juvenile arthritis and anorexia nervosa or those undergoing cancer treatment are at increased risk for bone mass deficiencies, fracture or osteoporosis as they get older, according to a new study whose lead author is a researcher at Cincinnati Children's Hospital Medical Center.

8 Jun 2007

Newer iodine-containing contrast agents safe for children

Allergic-like reactions to newer iodine-containing contrast agents (nonionic contrast media), are rare in children according to a recent study conducted by researchers from the University of Michigan Medical Center and C.S. Mott Children's Hospital both in Ann Arbor.

8 Jun 2007

Lack of sun, low vitamin D and the elderly

It's not yet clear why overweight elderly adults have low levels of vitamin D in their blood.

8 Jun 2007

Time-of-flight positron emission tomography provides benefits for cancer patients

Moving from computer simulation to patient images, researchers are now demonstrating the benefits that time-of-flight (TOF)/PET (positron emission tomography) imaging can provide for cancer patients.

5 Jun 2007

Combining molecular imaging technologies to stop/prevent heart attacks

The use of combined imaging technologies may hold the key to stopping and even preventing heart attacks, according to research reported at the 54th Annual Meeting of SNM, the world's largest society for molecular imaging and nuclear medicine professionals.

5 Jun 2007

Molecular imaging provides a better way to visualize heart disease

Technically advanced molecular imaging provides a 3-D way to significantly improve the diagnosis of heart disease, according to researchers at the 54th Annual Meeting of SNM, the world's largest molecular imaging and nuclear medicine society.

5 Jun 2007

Designer lipid-like peptides to play a key role in improving drug delivery systems

Scientists from Institute of Biophysics and Nanosystems Research (IBN), Austrian Academy of Sciences and of Centre for Biomedical Engineering, Massachusetts Institute of Technology, Cambridge, USA report the study of Tuning Curvature and Stability of Monoolein Bilayers by Designer Lipid-Like Peptide Surfactants in the May 30th issue of the online, open-access journal PLoS ONE.

30 May 2007