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Monash University software helps tackle cancer and aircraft design

A powerful software tool designed by academics at Monash University is being used in the UK to help develop cancer treatments and improve aircraft engine design.

2 Aug 2005

Valuable clues for rational antimalarial drug design and vaccine development

By determining the molecular structure of a protein that enables malaria parasites to invade red blood cells, researchers have uncovered valuable clues for rational antimalarial drug design and vaccine development. The findings are reported in the July 29 issue of the journal Cell.

28 Jul 2005

Combined computed tomography (CT) and positron emission tomography (PET) - may detect the spread of head and neck cancer more accurately

"PET/CT is very helpful in determining where we should pinpoint our biopsies for recurrent disease," said Dr. Carol Shores, assistant professor of otolaryngology/head and neck surgery at UNC and the report's senior author. Shores is a member of the UNC Lineberger Comprehensive Cancer Center.

26 Jul 2005

Positron emission tomography (PET) imaging can identify effectiveness of chemotherapy early in high-risk breast cancer patients

The effectiveness of chemotherapy in patients with advanced breast cancer can be evaluated earlier by using 18F-FDG positron emission tomography (PET) imaging over other conventional imaging procedures, according to an article in the July issue of the Society of Nuclear Medicine's Journal of Nuclear Medicine.

26 Jul 2005

Maintaining a healthy weight in children may be one good way to keep a healthy blood lipid profile and a happy heart

A study of 400 high school age children with a variety of fitness and fatness levels showed that fatter youths had unfavorable lipid profiles, including higher levels of triglycerides and higher ratios of total cholesterol to the protective HDL cholesterol or high density lipoprotein.

21 Jul 2005

Videotaping advance directives would allow people to express medical decisions to their physicians and families more easily

Ray Moseley sees the trouble with advance health-care directives every time he speaks to a group of senior citizens: Several in the crowd always know someone who had a living will but whose end-of-life decisions were not honored anyway.

19 Jul 2005

Scientists determine the structures of eight proteins in just 10-20 days per protein

A University at Buffalo scientist created a stir in 2003 when he announced a much faster, more precise and far less expensive method of obtaining nuclear magnetic resonance (NMR) data to map a protein's atomic structure. Genomics researchers were fascinated, but some also were a bit skeptical.

18 Jul 2005

Dental X-rays effectively identify stroke risk

General dentists from across the United States exchanged vital information today showing that dental X-rays, known as panoramic radiographs, used for oral health examinations, are effective in detecting some cases of clinically significant carotid artery stenosis, or blockages in the carotid artery, which can potentially lead to stroke.

15 Jul 2005

White blood cell called a neutrophil appears to be crucial to abdominal aortic aneurysm formation

Each year, 200,000 Americans find out that the largest blood vessel in their body, the aorta, may burst open at any time. About 20,000 die suddenly from such a rupture. And another 36,000 have surgery to repair or replace the swelling section of aorta before time runs out.

13 Jul 2005

Biologists determine structure of a common-cold virus

Biologists at Purdue University have determined the combined structure of a common-cold virus attached to a molecule that enables the virus to infect its host, information that ultimately may help researchers develop methods for treating certain viral infections.

13 Jul 2005

X-ray crystallography images show how a protein called alpha-actinin performs molecular ballet

As a cell moves forward, physical stress on its skeleton triggers molecular fingers and arms to grasp each other in reinforcing links that stabilize the skeleton, according to images produced by investigators at St. Jude Children's Research Hospital.

12 Jul 2005

X-ray measurements help determine whether chronic problems with the hard-to-reach frontal sinuses can be corrected with surgery

"The frontal sinus is behind the forehead and it has a very tortuous drainage," says Dr. Stil E. Kountakis, vice chair of the Medical College of Georgia Department of Otolaryngology-Head and Neck Surgery. "It's the most difficult sinus to work with."

6 Jul 2005

Drug abusers are increasingly turning to a slow-release form of drug fentanyl

Drug abusers are increasingly turning to a slow-release form of a powerful painkiller for a quick and dangerous high, University of Florida researchers warn. The trend is raising alarm as the number of people dying from an overdose of the drug fentanyl, an opioid 100 times more potent than morphine, rises.

6 Jul 2005

Daclizumab effective at reducing organ rejection and risk of infection in heart transplant patients

A new study shows that a drug, called daclizumab, is effective at reducing organ rejection and risk of infection in heart transplant patients. The multi-center study by cardiologists from the United States, Sweden, Germany and Canada will be published in the June 30 issue of The New England Journal of Medicine.

30 Jun 2005

Tetracycline antibiotic shows promise for treating osteoarthritis

A tetracycline antibiotic, doxycycline, has been successfully used to treat a wide-range of bacterial infections. In addition to its effects as an antibiotic, doxycycline has other actions as a drug and, in laboratory studies with animals and with human tissue, can inhibit the degradation of cartilage in a way that could be useful for the treatment of osteoarthritis (OA).

28 Jun 2005

Patients with rheumatoid arthritis are at increased risk of coronary artery disease

The findings of research published today in Arthritis Research & Therapy show that CAD is accelerated in RA patients, and patients with both RA and CAD are at an increased risk of death from heart disease.

28 Jun 2005

Scientists solve structure of a critical innate immune system protein

Scientists at The Scripps Research Institute have solved the structure of a crucial human immune system molecule called TLR3, an acronym for Toll-like receptor three. In an upcoming issue of the journal Science, the protein is described as a large horseshoe-shaped coil composed of 23 leucine-rich repeats (LRRs).

27 Jun 2005

Pioneering new thyroid treatment

The doctor has developed a revolutionary technique for treating hyperthyroidism, also known as Graves' Disease. And earlier this month, Culham became the first person in North America to undergo the new procedure.

21 Jun 2005

Dartmouth Medical School collaboration in Tanzania may alter assumptions about the diagnosis of tuberculosis in HIV-infected people

New findings from a Dartmouth Medical School collaboration in Tanzania may alter assumptions about the diagnosis of tuberculosis in HIV-infected people, and prompt a major change in way TB testing is routinely done in the developing world.

15 Jun 2005

Walking more slowly, obese individuals can burn more calories per mile and may reduce the risk of arthritis or joint injury

Leisurely walking for distance combined with low-impact cardiovascular activity appears to be the best formula for obese people seeking to get into shape and stay healthy, according to a University of Colorado at Boulder study.