immunity News and Research

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Mathematical model of host immune response to SARS-CoV-2 demonstrates that age-related risk factors increased viral load

Researchers evaluated the host immune responses to SARS-CoV-2 and its prolonged symptoms.

21 Feb 2022

Biochemical changes in lung physiology not responsible for severe clinical outcomes in the older population

Researchers investigated whether age-dependent changes in lung physiology make the elderly disproportionately susceptible to SARS-CoV-2 infection.

21 Feb 2022

The relative contagiousness of the Alpha, Delta, and Omicron SARS-CoV-2 variants

A new study, available on the arXiv* server, proposes a simple dynamic model for estimating the relative contagiousness of two variants of SARS-CoV-2, namely Alpha and Delta. Furthermore, it demonstrates how to compute the effective reproduction number for a new variant without contemporaneous sequencing results. This is important to assess the state of the pandemic in real-time.

20 Feb 2022

Researchers develop novel anti-SARS-CoV-2 Omicron vaccine candidate

Researchers have developed a new vaccine candidate that is specifically targeted against the SARS-CoV-2 Omicron variant.

20 Feb 2022

T-cell responses linked with protection from SARS-CoV-2 infection in vaccinated individuals with or without cancer

T-cell responses directed against the receptor-binding domain of the SARS-CoV-2 spike protein were associated with protection from SARS-CoV-2 infection in vaccinated individuals with or without cancer, with lower T-cell responses observed in patients with blood cancers.

18 Feb 2022

Codiak's publication highlights the ability of exoASO-STAT6 to selectively target tumor-associated macrophages

Codiak BioSciences, Inc., a clinical-stage biopharmaceutical company pioneering the development of exosome-based therapeutics as a new class of medicines, today announced the online publication of a new manuscript, Exosome mediated genetic reprogramming of tumor associated macrophages by exoASO-STAT6 leads to potent monotherapy anti-tumor efficacy, in the American Association for the Advancement of Science's journal, Science Advances.

18 Feb 2022

Study characterizes COVID-19 vaccine effectiveness at longer dose intervals

Researchers conducted a prospective cohort study to assess the level and durability of protection offered by two doses of COVID-19 vaccine against SARS-CoV-2 infection in participants with no history of a previous infection.

18 Feb 2022

Demonstrating effectiveness of BNT162b2 vaccine in preventing reinfections after COVID-19 recovery

Researchers conducted a retrospective cohort study to assess the rate of SARS-CoV-2 reinfection in patients who had recovered from COVID-19.

18 Feb 2022

Meta-analysis of population-based seroprevalence studies to estimate SARS-CoV-2 seroprevalence in Africa

Researchers conducted a descriptive meta-analysis to estimate the seroprevalence of SARS-CoV-2 infections in Africa.

18 Feb 2022

Response of peripheral immune cells to ex vivo SARS-CoV-2 exposure compared to SARS-CoV

Researchers characterized the responses of the PBMCs at the individual cell and cell type levels against SARS-CoV-2 and SARS-CoV ex vivo.

18 Feb 2022

Study explores efficacy of mRNA vaccine booster doses during the SARS-CoV-2 Omicron wave

Researchers evaluated the efficacy of an mRNA vaccine booster dose against severe acute respiratory syndrome coronavirus-2 during the Omicron surge.

18 Feb 2022

Immunogenicity, efficacy, and safety of BNT162b2 or mRNA1273 fourth dose

A recent study explored the safety, immunogenicity, and VE of the SARS-CoV-2 mRNA BNT162b2 and mRNA1273 vaccines against its Omicron VOC in HCWs in Israel.

18 Feb 2022

mRNA vaccine-induced antibodies shown to be more effective in neutralizing SARS-CoV-2 and its variants than natural immunity

Researchers designed an electrochemiluminescence-based serology test with remarkable sensitivity to precisely quantify the amounts of anti-RBD antibodies in individuals infected with SARS-CoV-2.

18 Feb 2022

Role of quantitative, multiplexed, targeted proteomics in determining variant-specific SARS-CoV-2 antibody response

Researchers developed a ‘bait and capture’ system which was further followed by a multiplexed and targeted proteomic liquid chromatography-tandem mass spectrometry analyses for the comparison of immune correlates in response to vaccination, natural infection, as well as protection against SARS-CoV-2 variants.

18 Feb 2022

New finding may aid in development of vaccines against future animal-to-human viral diseases

A future vaccine providing protection against a wide range of coronaviruses that jump from their original animal hosts to humans -; including SARS-CoV-2, the cause of COVID-19 -; may be possible, say Johns Hopkins Medicine researchers, based on findings from their recent study.

17 Feb 2022

immunity News and Research

Mathematical model of host immune response to SARS-CoV-2 demonstrates that age-related risk factors increased viral load

Biochemical changes in lung physiology not responsible for severe clinical outcomes in the older population

The relative contagiousness of the Alpha, Delta, and Omicron SARS-CoV-2 variants

Researchers develop novel anti-SARS-CoV-2 Omicron vaccine candidate

T-cell responses linked with protection from SARS-CoV-2 infection in vaccinated individuals with or without cancer

Codiak's publication highlights the ability of exoASO-STAT6 to selectively target tumor-associated macrophages

Study characterizes COVID-19 vaccine effectiveness at longer dose intervals

Demonstrating effectiveness of BNT162b2 vaccine in preventing reinfections after COVID-19 recovery

Meta-analysis of population-based seroprevalence studies to estimate SARS-CoV-2 seroprevalence in Africa

Response of peripheral immune cells to ex vivo SARS-CoV-2 exposure compared to SARS-CoV

Study explores efficacy of mRNA vaccine booster doses during the SARS-CoV-2 Omicron wave

Immunogenicity, efficacy, and safety of BNT162b2 or mRNA1273 fourth dose

mRNA vaccine-induced antibodies shown to be more effective in neutralizing SARS-CoV-2 and its variants than natural immunity

Role of quantitative, multiplexed, targeted proteomics in determining variant-specific SARS-CoV-2 antibody response

New finding may aid in development of vaccines against future animal-to-human viral diseases

Study explores humoral and cellular immunity conferred by second and third COVID-19 BNT162b2 vaccination in elderly

COVID-19 vaccine-induced immunity in heart and kidney solid organ transplant recipients

Study explores differential immune responses against SARS-CoV-2 in adults and children

Vaccination likely to be more protective against SARS-CoV-2 viral variants than natural infection

mRNA COVID-19 vaccine shown to induce afucosylated antibodies in individuals without prior SARS-CoV-2 exposure

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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