immunity News and Research

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Insufficient drug exposure most likely to cause COVID-19 rebound

Paxlovid is the leading oral medication for preventing severe cases of COVID-19 in high-risk individuals.

21 Jun 2022

Wistar scientists discover a new way to boost a person's immune response to tumors

Due to the development of resistance to chemotherapy and recurring tumors, patients with ovarian cancer often have low survival rates.

21 Jun 2022

Vaccination uptake found to be critical to limiting COVID-19 transmission during variant-driven surges

US states with low vaccination rates bore the brunt of the COVID-19 surge caused by the Delta variant during the summer of 2021, says a study published today in eLife.

21 Jun 2022

Researchers discover the skin's natural protection from nighttime bacterial invasion in mice

Researchers at Kyoto University have discovered the skin's natural protection from nighttime bacterial invasion in mice, which may provide a basis for eventually developing a drug treatment.

21 Jun 2022

Researchers compare the development and persistence of antibody and T-cell responses elicited by the mRNA BNT162b2 vaccine or SARS-CoV-2 infection

Researchers comparatively assessed the generation of B lymphocyte-mediated antibody responses and T lymphocyte-mediated cellular responses between mRNA BNT162b vaccinees and mild COVID-19 patients.

21 Jun 2022

Only 20% of Americans have effective protection against Omicron infection

In a recent research paper published in the Clinical Infectious Diseases journal, scientists analyzed the population immunity against pre-Omicron and Omicron severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) variants in U.S. counties and states up until December 1, 2021. Background

21 Jun 2022

Clonal diversity impacts longevity of T cell reaction specific to SARS-CoV-2 epitope

A recent article under review at the Nature Portfolio journal and currently available on the Research Square* preprint server analyzed the factors influencing the durability of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epitope-specific T cell reaction.

21 Jun 2022

After maternal COVID vaccination, infants have persistent anti-SARS-CoV-2 antibodies at 3 months

A recent article published in the journal Clinical Infectious Diseases assessed the kinetics of anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies derived from mothers among infants in association with the timing of prenatal SARS-CoV-2 vaccination.

21 Jun 2022

An estimate of Omicron's fitness advantage

Researchers quantify the transmission advantage of the SARS-CoV-2 Omicron variant across forty countries.

21 Jun 2022

How specific comorbidities impact severity of COVID-19

Researchers identify the association between severe COVID-19 and specific comorbidities.

20 Jun 2022

Each SARS-CoV-2 reinfection causes more severe disease

In a recent study under review at the Nature Portfolio journal and currently posted to the Research Square* preprint server, researchers at Washington University School of Medicine and VA Saint Louis Health Care System showed that acute severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reinfection adds to the risks of all-cause mortality and hospitalization accrued during the first SARS-CoV-2 infection.

20 Jun 2022

Implications of impaired type I interferon immunity and increasing COVID-19 severity

Researchers demonstrated that impaired type I interferon immunity is associated with increasing coronavirus disease 2019 severity.

20 Jun 2022

Gut microbiome acts on the brain to control appetite

Hypothalamic GABAergic neurons recognize microbial muropeptides through the cytosolic receptor NOD2, which regulates food intake and body temperature.

19 Jun 2022

Study points to a new direction for the development of NAMPT-targeted cancer therapies

In this new article publication from Acta Pharmaceutica Sinica B, authors Ying Wu, Congying Pu, Yixian Fu, Guoqiang Dong, Min Huang and Chunquan Sheng from Second Military Medical University, Shanghai, China and University of Chinese Academy of Sciences, Shanghai, China discuss how NAMPT-targeting PROTAC promotes antitumor immunity via suppressing myeloid-derived suppressor cell expansion.

18 Jun 2022

immunity News and Research

Insufficient drug exposure most likely to cause COVID-19 rebound

Wistar scientists discover a new way to boost a person's immune response to tumors

Vaccination uptake found to be critical to limiting COVID-19 transmission during variant-driven surges

Researchers discover the skin's natural protection from nighttime bacterial invasion in mice

Researchers compare the development and persistence of antibody and T-cell responses elicited by the mRNA BNT162b2 vaccine or SARS-CoV-2 infection

Only 20% of Americans have effective protection against Omicron infection

Clonal diversity impacts longevity of T cell reaction specific to SARS-CoV-2 epitope

After maternal COVID vaccination, infants have persistent anti-SARS-CoV-2 antibodies at 3 months

An estimate of Omicron's fitness advantage

How specific comorbidities impact severity of COVID-19

Each SARS-CoV-2 reinfection causes more severe disease

Implications of impaired type I interferon immunity and increasing COVID-19 severity

Gut microbiome acts on the brain to control appetite

Study points to a new direction for the development of NAMPT-targeted cancer therapies

Research may open door to the design of a better structured rabies vaccine

Effectiveness of previous COVID-19 and vaccination against SARS-CoV-2 Omicron infection

HIV coinfection significantly impacts B cell response to SARS-CoV-2

Oral immunotherapy for peanut allergies is highly effective when started for infants under 12 months

Combination drug strategy activates natural killer cell-mediated immunity to attack tumors

Effectiveness of a hybrid vaccine against COVID-19 and influenza

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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