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Insufficient Th1 polarisation blocks RCC vaccine efficacy

A lack of a clinical response to an allogenic gene-modified renal cell cancer vaccine may be due to insufficient type 1 T-helper cell polarisation, show results of a gene expression profiling study.

30 Oct 2014

Major research project aims to reduce chances of hair loss after chemotherapy treatment

Cancer suffers who lose their hair as a consequence of chemotherapy will benefit from a major research project that will improve the scalp cooling technology that prevents hair loss.

From Paxman 30 Oct 2014

Novel 'designer' nanodevice could improve cancer diagnostics, treatment

Cancer diagnostics and treatment options could be drastically improved with the creation of a 'designer' nanodevice being developed by researchers from the UK, Italy, the US and Argentina.

22 Oct 2014

Identifying infections rapidly: an interview with Dr. David J. Ecker

Current methods for diagnosing infectious diseases are based on the 150-year-old culture method, where physicians collect a sample of a patient’s tissue, such as blood, mucus or urine, and transfer it onto media bottle to allow the pathogens to grow.

From Abbott Diagnostics 20 Oct 2014

Scientists develop promising vaccination strategy to counteract RSV infection

Respiratory Syncytial Virus causes severe respiratory tract infections and worldwide claims the lives of 160,000 children each year. Scientists at VIB and Ghent University have succeeded in developing a promising vaccination strategy to counteract this common virus infection.

17 Oct 2014

Females' natural resistance to bacterial pneumonia is linked to NOS3 enzyme

Researchers have linked increased resistance to bacterial pneumonia in female mice to an enzyme activated by the female sex hormone estrogen.

17 Oct 2014

Nanotechnology expert from PETA Science Consortium to outline hazard testing strategy at ECHA workshop

The PETA International Science Consortium's nanotechnology expert will present a poster titled "A Tiered-Testing Strategy for Nanomaterial Hazard Assessment" at the Topical Scientific Workshop – Regulatory Challenges in Risk Assessment of Nanomaterials being organized by the European Chemicals Agency (ECHA) on October 23 and 24 in Helsinki.

17 Oct 2014

Promising vaccination strategy to counteract RSV

16 Oct 2014

Scientists combine new type of nanoparticle with photodynamic therapy to kill cancer cells

An international group of scientists led by Gang Han, PhD, at the University of Massachusetts Medical School, has combined a new type of nanoparticle with an FDA-approved photodynamic therapy to effectively kill deep-set cancer cells in vivo with minimal damage to surrounding tissue and fewer side effects than chemotherapy. This promising new treatment strategy could expand the current use of photodynamic therapies to access deep-set cancer tumors.

16 Oct 2014

LaVision BioTec report on users of light sheet microscopy in the Miami Project to Cure Paralysis

LaVison BioTec, developers of advanced microscopy solutions for the life sciences, report on users of their Ultramicroscope Light Sheet Fluorescence Microscope system to aid the research of the Miami Project to Cure Paralysis under the supervision of Professor Vance Lemmon, the Walter G. Ross Distinguished Chair in Developmental Neuroscience & Professor of Neurological Surgery at the University of Miami.

14 Oct 2014

Researchers generate fruit fly model, unveil key genetic factors behind human colon cancer

Researchers at the Institute for Research in Biomedicine (IRB Barcelona) have managed to generate a fruit fly (Drosophila melanogaster) model that reproduces human colon cancer. With two publications appearing in PLoS One and EMBO Reports, the IRB team also unveil the function of a key gene in the development of the disease.

9 Oct 2014

New England Biolabs inks deal to supply critical reagents to TriLink BioTechnologies

New England Biolabs, Inc. (NEB®) has strengthened its position as a key supplier to the fast-growing RNA synthesis market by signing an agreement to supply critical reagents to TriLink BioTechnologies, Inc., a leading manufacturer of mRNA and long RNA for research, diagnostic and therapeutic applications.

From New England Biolabs 7 Oct 2014

Absorption Systems supports Pediatric Praziquantel Consortium led by Merck KGaA

Absorption Systems, a leader in preclinical contract testing of drugs, biologics, and medical devices, announces that it has been subcontracted by the German pharmaceutical company Merck KGaA to work on a new pediatric formulation of praziquantel.

7 Oct 2014

Researchers find potential new way to better control immune-mediated diseases

Researchers at University of California, San Diego School of Medicine have discovered that T-cells - a type of white blood cell that learns to recognize and attack microbial pathogens - are activated by a pain receptor.

6 Oct 2014

Sigma-Aldrich enters into agreement to acquire Cell Marque to better serve IHC customers

Sigma-Aldrich Corporation announced today that it has entered into an agreement to acquire Rocklin, California, based Cell Marque Corporation in a move to strengthen its antibody portfolio and to better serve immunohistochemistry (IHC) customers.

3 Oct 2014

Columbia Laboratories' subsidiary to unveil ROADMAP to Clinical Trials platform at CPhI/ICSE event

Columbia Laboratories, Inc., today announced that its subsidiary, Molecular Profiles Ltd., is set to unveil the ROADMAP to Clinical Trials platform at the annual CPhI/ICSE Worldwide event in Paris next week, which aims to support companies with the rapid development of both standard and complex drug products.

1 Oct 2014

Researchers create new Cas9 animal model for in vivo genome editing experiments

Researchers from the Broad Institute and Massachusetts Institute of Technology have created a new mouse model to simplify application of the CRISPR-Cas9 system for in vivo genome editing experiments.

29 Sep 2014

Lung-MAP, ALCHEMIST clinical trials offer innovative study designs for lung cancer patients

The recent launch of two clinical trials offer innovative study designs for patients with lung cancer. These clinical trials are the direct result of a National Cancer Institute sponsored workshop chaired by Drs. Fred R. Hirsch, Shakun Malik and Claudio Dansky- Ullman, that brought together the NCI Thoracic Malignancies Steering Committee, the US Food and Drug Administration, academicians, clinicians as well as industry and government stakeholders to discuss issues and challenges related to clinical trial design and biomarkers for lung cancer targeted-therapies.

29 Sep 2014

Research: Skin cells from pediatric patients can be used in tissue-engineered pulmonary valves

Researchers have found a way to take a pediatric patient's skin cells, reprogram the skin cells to function as heart valvular cells, and then use the cells as part of a tissue-engineered pulmonary valve.

24 Sep 2014

AIT, BioVendor and SCIENION partner to develop in-vitro diagnostic test for colon cancer

The AIT Austrian Institute of Technology, BioVendor and SCIENION today announced that the three companies will partner on the development of an in-vitro diagnostic test for colon cancer. The innovative test kit shall identify cancer at an early stage based on tumor autoantibody biomarkers.

24 Sep 2014

in vitro News and Research

Insufficient Th1 polarisation blocks RCC vaccine efficacy

Major research project aims to reduce chances of hair loss after chemotherapy treatment

Novel 'designer' nanodevice could improve cancer diagnostics, treatment

Identifying infections rapidly: an interview with Dr. David J. Ecker

Scientists develop promising vaccination strategy to counteract RSV infection

Females' natural resistance to bacterial pneumonia is linked to NOS3 enzyme

Nanotechnology expert from PETA Science Consortium to outline hazard testing strategy at ECHA workshop

Promising vaccination strategy to counteract RSV

Scientists combine new type of nanoparticle with photodynamic therapy to kill cancer cells

LaVision BioTec report on users of light sheet microscopy in the Miami Project to Cure Paralysis

Researchers generate fruit fly model, unveil key genetic factors behind human colon cancer

New England Biolabs inks deal to supply critical reagents to TriLink BioTechnologies

Absorption Systems supports Pediatric Praziquantel Consortium led by Merck KGaA

Researchers find potential new way to better control immune-mediated diseases

Sigma-Aldrich enters into agreement to acquire Cell Marque to better serve IHC customers

Columbia Laboratories' subsidiary to unveil ROADMAP to Clinical Trials platform at CPhI/ICSE event

Researchers create new Cas9 animal model for in vivo genome editing experiments

Lung-MAP, ALCHEMIST clinical trials offer innovative study designs for lung cancer patients

Research: Skin cells from pediatric patients can be used in tissue-engineered pulmonary valves

AIT, BioVendor and SCIENION partner to develop in-vitro diagnostic test for colon cancer

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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