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Quanterix's ELISA precisely measures low abundance cytokines in Crohn's disease

Quanterix Corporation, a company enabling a new generation of molecular diagnostic tests based on its revolutionary Single Molecule Array technology, today announced results of a pilot study to measure biomarkers of inflammation from patients with Crohn's disease.

20 Aug 2011

New findings on cancer stem cells

In cancer, tumors aren't uniform: they are more like complex societies, each with a unique balance of cancer cell types playing different roles. Understanding this "social structure" of tumors is critical for treatment decisions in the clinic because different cell types may be sensitive to different drugs. A common theory is that tumors are a hierarchical society, in which all cancer cells descend from special self-renewing cancer stem cells.

20 Aug 2011

NIH/NINDS awards AMRI to develop pre-clinical drug candidate for spinal muscular atrophy

AMRI today announced it received a federal contract award from the National Institutes of Health (NIH)/National Institute of Neurological Disorders and Stroke (NINDS) to provide chemistry and other drug discovery technologies in support of NINDS' Medicinal Chemistry for Neurotherapeutics Program (MCNP), part of the NIH Blueprint Neurotherapeutics Network.

19 Aug 2011

Scientists uncover how human egg captures sperm to begin fertilisation process

Researchers have uncovered exactly how a human egg captures an incoming sperm to begin the fertilisation process, in a new study published this week in the journal Science.

19 Aug 2011

Human embryonic stem cell, iPS-derived progeny are similar and developmentally immature

Stem cell researchers at UCLA have discovered that three types of cells derived from human embryonic stem cells and induced pluripotent stem cells are similar to each other, but are much more developmentally immature than previously thought when compared to those same cell types taken directly from human tissue.

18 Aug 2011

FDA approves Zelboraf (vemurafenib) for advanced skin cancer

A new drug was approved for advanced skin cancer this Wednesday by U.S. regulators, offering the first new treatment for melanoma in 13 years.

18 Aug 2011

Zelboraf receives FDA approval for treatment of metastatic melanoma

The U.S. Food and Drug Administration today approved Zelboraf (vemurafenib), a drug to treat patients with late-stage (metastatic) or unresectable (cannot be removed by surgery) melanoma, the most dangerous type of skin cancer.

17 Aug 2011

Patrys product shows activity in multiple myeloma cancer cells

Patrys Limited today announced the results of preclinical work conducted at The University Hospital of Würzburg showing the activity of one of Patrys’ products in multiple myeloma.

16 Aug 2011

China Medical first fiscal quarter net revenues increase 27.4% to US$36.7 million

China Medical Technologies, Inc., a leading China-based advanced in-vitro diagnostic company, announced its unaudited financial results for the first fiscal quarter ended June 30, 2011 today.

16 Aug 2011

Biochemist develops polymer material to convert precursor cells into functional neurones

Nervous system diseases are especially difficult to treat, as it is not easy to replace the parts of the neural puzzle which are damaged. The key is in developing functional neurons from in vitro-treated, cells but for this it is essential that the support on which these cells are based simulate the characteristics of the nervous system.

16 Aug 2011

Human Genome Sciences, 4-Antibody sign collaboration agreement

4-Antibody AG today announced the signing of a collaboration agreement with Human Genome Sciences (HGS) to discover and develop fully human therapeutic antibodies.

16 Aug 2011

Caffeine in sunscreens may protect from skin cancer: Study

Studies have revealed that drinking caffeinated beverages reduces one’s chances of developing some types of cancer, including UV-associated skin cancer. Now, researchers propose a possible mechanism for this observation—the inhibition of a DNA repair pathway that sensitizes cells to death after sun exposure.

15 Aug 2011

Blocking type 2 receptor reduces PDA cell growth with the activation of AMPK enzyme

Pancreatic cancer researchers at Thomas Jefferson University have shown, for the first time, that blocking a receptor of a key hormone in the renin-angiotensin system (RAS) reduces cancer cell growth by activating the enzyme AMPK to inhibit fatty acid synthase, the ingredients to support cell division.

11 Aug 2011

NCI, Genesis Biopharma sign CRADA agreement to develop cancer immunotherapies

Genesis Biopharma, Inc., a biotechnology company developing targeted cancer immunotherapies, today announced it has signed a Cooperative Research and Development Agreement (CRADA) with the National Cancer Institute.

10 Aug 2011

China Medical receives SFDA approvals for TOP2A and prostate cancer FISH detection kits

China Medical Technologies, Inc., a leading China-based advanced in-vitro diagnostic company, today announced that it has received approvals for its prostate cancer FISH detection kit and Topoisomerase 2-alpha FISH detection kit from the State Food and Drug Administration of the People's Republic of China.

10 Aug 2011

Test for ticking biological clock

Researchers from St Andrews University, Scotland have been able to chart the levels of a vital fertility hormone in women of different ages thus essentially detect their biological clocks.

9 Aug 2011

Leica Microsystems, CMED partner to co-develop and market automated FISH kits

China Medical Technologies, Inc. (CMED), a leading China-based advanced in-vitro diagnostic ("IVD") company, and Leica Biosystems, a division of Leica Microsystems, a world leader in microscopes and scientific instruments, today announced that they have established a sales, research and development collaboration to co-develop and market automated FISH kits to be used on the Leica BOND system.

8 Aug 2011

Stem cells could provide sperm for infertile males

Researchers have been successful in creating sperm-producing germ cells from stem cells in a lab and transferred them into infertile mice, which after the treatment were able to produce healthy offspring. This new development could help thousands of infertile men become fathers if the method proves similarly effective in humans.

5 Aug 2011

Key protein discoveries could lead to new lung repair therapies for children, adults

A team at The Saban Research Institute of Children's Hospital Los Angeles has made crucial discoveries about the role of key proteins in wound healing in the tiny air sacs in the lungs known as "alveoli" that could lead to new therapies for children and adults.

5 Aug 2011

Virginia Tech student receives prestigious award for cellular signaling receptor study linked to diabetes, obesity

Stephanie Nicole "Nikki" Lewis, a graduate student in the interdisciplinary doctoral program in genetics, bioinformatics, and computational biology at Virginia Tech, has been awarded the prestigious Ruth L. Kirschstein National Research Service Award for Predoctoral Research through the National Institutes of Health for her study of a cellular signaling receptor that is associated with chronic inflammatory diseases such as diabetes, obesity, and inflammatory bowel disease.

5 Aug 2011

in vitro News and Research

Quanterix's ELISA precisely measures low abundance cytokines in Crohn's disease

New findings on cancer stem cells

NIH/NINDS awards AMRI to develop pre-clinical drug candidate for spinal muscular atrophy

Scientists uncover how human egg captures sperm to begin fertilisation process

Human embryonic stem cell, iPS-derived progeny are similar and developmentally immature

FDA approves Zelboraf (vemurafenib) for advanced skin cancer

Zelboraf receives FDA approval for treatment of metastatic melanoma

Patrys product shows activity in multiple myeloma cancer cells

China Medical first fiscal quarter net revenues increase 27.4% to US$36.7 million

Biochemist develops polymer material to convert precursor cells into functional neurones

Human Genome Sciences, 4-Antibody sign collaboration agreement

Caffeine in sunscreens may protect from skin cancer: Study

Blocking type 2 receptor reduces PDA cell growth with the activation of AMPK enzyme

NCI, Genesis Biopharma sign CRADA agreement to develop cancer immunotherapies

China Medical receives SFDA approvals for TOP2A and prostate cancer FISH detection kits

Test for ticking biological clock

Leica Microsystems, CMED partner to co-develop and market automated FISH kits

Stem cells could provide sperm for infertile males

Key protein discoveries could lead to new lung repair therapies for children, adults

Virginia Tech student receives prestigious award for cellular signaling receptor study linked to diabetes, obesity

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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