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Non-profit public-private partnership develops affordable, new drug regimens for tuberculosis

The Global Alliance for TB Drug Development (TB Alliance), a non-profit public-private partnership developing affordable, new drug regimens for tuberculosis, today announced the start of Phase I clinical trials for the lead TB drug in its pipeline, PA-824. The trials begin this month.

14 Jun 2005

Findings could lead to a new approach in diagnosing and treating Alzheimer’s disease

The human body has its own defense against brain aging: the innate immune system, which helps to clean the brain of amyloid-beta waste products. However, UCLA researchers discovered that some patients with Alzheimer’s disease have an immune defect making it difficult to clean away these wastes.

From MP Biomedicals, LLC 10 Jun 2005

Omega-3 combined with propofol may lead to new drugs to treat breast cancer

Omega-3, the fatty acid found in oily fish, could be combined with a commonly used anesthetic to develop drugs to treat breast cancer, according to research published in the journal Breast Cancer Research.

8 Jun 2005

HIV protease inhibitors block programmed cell death in vivo

The immunodeficiency that arises in HIV may be due to excessive programmed cell death of immune CD4 T cells.

3 Jun 2005

Triple approach is promising against cancer cells

A trimodal treatment strategy combining chemotherapy, radiation therapy, and a protein kinase inhibitor is much more effective against cancer cells than any combination of only two treatment methods.

1 Jun 2005

Baby boy is first successful birth in Canada from frozen eggs

McGill University Health Center (MUHC) in Montreal yesterday announced the first successful birth in Canada resulting from frozen eggs. A healthy baby boy, weighing 3740 grams was born on April 29 to a 26-year-old mother who had suffered from infertility for two years.

31 May 2005

A new technique might allow women diagnosed with cancer the opportunity to have children when chemotherapy and radiation treatments rob them of their fertility

Freezing eggs is one thing; thawing them safely so they can lead to pregnancy is the challenge. In the past, efforts to freeze a woman's eggs, or oocytes, have not worked well because the cells are large. When the egg is thawed, ice crystals cause damage that prevents the egg from being fertilized.

29 May 2005

U.S. House of Representatives approve two bills on stem-cell research

Two new bills related to stem-cell research have been approved by the U.S. House of Representatives one promoting non-destructive methods and the other supporting research resulting in the death of unborn children.

26 May 2005

The National Infertility Association joins infertility groups to Support Stem Cell Research Enhancement Act

The National Infertility Association joins with the American Society for Reproductive Medicine (ASRM) and the American Fertility Association in support of the Stem Cell Research Enhancement Act, HR 810.

23 May 2005

FDA recommends approval of the investigational anti-HIV drug tipranavir

Boehringer Ingelheim today announced that the U.S. Food and Drug Administration's (FDA) Antiviral Drugs Advisory Committee recommended the approval of the investigational anti-HIV drug tipranavir (11-3). Tipranavir is a non-peptidic protease inhibitor that requires boosting with low-dose ritonavir and must be used in combination with other antiretroviral agents.

20 May 2005

Premature use of stem cell therapy could put patients at risk

The premature use of stem cell therapy could put many patients at risk of viral or prion diseases unless appropriate safety systems are in place, warn experts in this week’s BMJ.

19 May 2005

UN wants ban on creation of smallpox virus in labs

Health officials around the world are being urged by United Nations experts to ban scientists from making the deadly smallpox virus in laboratories for fear it could fall into terrorist hands.

18 May 2005

Testosterone appears to benefit, not harm, cardiovascular health of middle-aged men

Although men suffer more coronary heart disease than women, the blame should not be placed on testosterone, according to a new study in the May 17, 2005, issue of the Journal of the American College of Cardiology.

18 May 2005

Two-sided coating could breathe life into medical implants

By mimicking an adhesive protein secreted by mussels and a polymer that repels cells and proteins, researchers at Northwestern University have designed a versatile new two-sided coating that could breathe life into medical implants.

15 May 2005

Simple and efficient method for creation of novel protein functions in an existing protein scaffold

By designing a molecular bridge, scientists at the University of Illinois at Urbana-Champaign have forged a successful pathway through a complex ocean of barriers: They've changed the function of a protein using a co-evolution approach.

8 May 2005

Stem-cell breakthrough gives new hope for IVF treatments

In a scientific first, human eggs have been grown in the laboratory using stem cells scraped from the surface of women's ovaries and the development raises the possibility of delaying menopause and providing a limitless source of donor eggs for in vitro fertilisation treatments and embryonic stem cell research.

5 May 2005

Little evidence found for IVF as most effective infertility treatment

In vitro fertilization can improve pregnancy rates among couples with unexplained infertility, but there is little evidence to show whether IVF results in more live births than other treatments, according to a new review of recent studies.

1 May 2005

British court gives the go ahead for IVF babies to be created to save sick siblings

Britain's highest appeal court has rejected a challenge from an anti-abortion group and has backed a 2003 Court of Appeal ruling that some couples undergoing the fertility treatment could have their embryos screened to find tissue matches for seriously ill children. The procedure will help save desperately ill children but some fear it could lead to the creation of babies for spare parts

1 May 2005

Quintuplets born to surrogate mother

In what is believed to be a world first, a surrogate mother has given birth to quintuplets.

26 Apr 2005

Guidelines for research involving human embryonic stem cells

The National Academies today recommended guidelines for research involving human embryonic stem cells, and urged all institutions conducting such research to establish oversight committees to ensure that the new guidelines will be followed.

26 Apr 2005