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New compound that is designed to overcome Gleevec resistance

One of the truly spectacular success stories in modern oncology is the development and implementation of Gleevec, a drug that virtually halts the progress of chronic myeloid leukemia. Yet for some patients who harbor particularly stubborn genetic mutations, Gleevec fails miserably.

17 Jul 2004

Animal bone implants that resemble natural bone

A team of researchers at the Institute of Bioengineering and Nanotechnology (IBN) has moved one step closer to developing an ideal bone scaffold for reconstructive surgery.

15 Jul 2004

Latest findings on HIV pathogenesis at AIDS Conference in Bangkok

At the XVth International AIDS Conference in Bangkok, Thailand, Anthony S. Fauci, M.D., director of the National Institute of Allergy and Infectious Diseases and chief of the NIAID Laboratory of Immunoregulation (LIR), will present his laboratory’s latest findings on how aberrant immune activation underlies HIV pathogenesis.

15 Jul 2004

Natural products to be developed as anti-cancer therapeutics

The licence grants Zentaris exclusive worldwide rights for the development, manufacture and marketing of disorazoles, a novel class of natural products with strong anti-cancer potential discovered by GBF researchers.

8 Jul 2004

Protein called Rac controls a number of biological processes and is directly implicated in several human diseases

Scientists at The Scripps Research Institute have described the regulatory mechanism of an important human protein called Rac that controls a number of biological processes and is directly implicated in several human diseases.

2 Jul 2004

Abnormalities observed in cloned mice help reinforce the need to continue to avoid the reproductive cloning of humans

Dr. Takumi Takeuchi, from Cornell University, New York, USA told a media briefing that he and Dr. Gianpiero Palermo's team had compared imprinting abnormalities (the process where specific genes inherited from both parents are silent) in mice embryos derived from assisted reproduction techniques and from cloning.

30 Jun 2004

Successes in frozen ovarian tissue technology may offer hope to women being treated for cancer

Doctors in Denmark have succeeded in producing a two-cell embryo after ovarian tissue was removed, frozen, and then thawed and replaced two years later.

29 Jun 2004

Chromosomal chaos in early embryonic development is linked to abnormalities in cytokinesis and spindle formation

Abnormalities in the spindles (the bi-polar thread like structures that link and pull the chromosomes during cell division) of human embryos before implantation may be the primary reason for many of the chromosome defects observed in early human development

29 Jun 2004

Studies show new massage and physical therapy technique increased pregnancy rates in infertile women

The researchers reported that the Wurn Technique(R) (patent pending) is highly effective at increasing fertility in both natural conception and in vitro fertilization (IVF). The therapy uses neither drugs nor surgery.

29 Jun 2004

SARS siRNA studied further to help many respiratory diseases including lung cancer

Intradigm Corporation, has announced achievement of prophylactic and therapeutic effects of siRNA (small interfering RNA) inhibitors of SARS-CoV in non-human primate cells. The results are published in the June 2004 issue of Antiviral Therapy (International Medical Press).

15 Jun 2004

Gestational diabetes is a type of diabetes, or high blood sugar, that only pregnant women get

Gestational diabetes is a type of diabetes, or high blood sugar, that only pregnant women get. If a woman is found to have high blood sugar when she's pregnant, but she never had high blood sugar before, she has gestational diabetes.

15 Jun 2004

Conflicting views on embryonic and adult stem cells complicate research in stem cell therapeutics

Though there has been considerable biological and political debate over the use of embryonic stem cells (ESCs) vs. adult stem cells (ASCs) as therapies for tissue engineering and organ transplants, inherent benefits and drawbacks in both techniques compel them to coexist and complement each other.

10 Jun 2004

Non-aspirin pain drugs may help men with recurrent prostate cancer

Early results from a University of North Carolina at Chapel Hill School of Medicine study may determine if drugs called Cox-2 inhibitors, a newer type of non-aspirin pain medicine now widely prescribed for arthritis symptoms, may benefit men with recurrent prostate cancer.

10 Jun 2004

Studies suggest white tea help prevent staphylococcus and streptococcus infections

New studies conducted at Pace University, have indicated that White Tea Extract (WTE) may have prophylactic applications in retarding growth of bacteria that cause Staphylococcus infections, Streptococcus infections, pneumonia and dental caries.

2 Jun 2004

Stent methodologies for treating occluded arteries

Branch points in the arteries are a common area of atherosclerotic disease, resulting in the occlusion of both branches. These branch points can generally be defined as a main branch and a side branch, and, in treating the disease, the question of what is the optimal course of action, opening the main branch, the side branch, or both, remains uncertain.

2 Jun 2004

More likely that older IVF mothers will suffer a pregnancy loss

It is a widely known that, as women age, it becomes more difficult for them to become pregnant. In a study from the Weill Medical College of Cornell University, researchers documented that it is also increasingly more likely that older IVF mothers will suffer a pregnancy loss, most often due to cytogenetic abnormalities of the fetus.

27 May 2004

Zengen announces positive results of treatment for vaginal yeast infection

Zengen Inc. announced today positive phase I/II results for its proprietary molecule CZEN-002 for the treatment of vulvovaginal candidiasis (VVC), commonly known as vaginal yeast infection.

25 May 2004

New series of clinical standards to diagnose heart attacks

Diagnosing heart attacks will become a more precise science thanks to the first of a new series of clinical standards just issued by the National Institute of Standards and Technology (NIST). Standard Reference Material (SRM) 2921 (human cardiac troponin complex) will help manufacturers develop and calibrate assays that measure specific protein concentrations in patient blood samples to determine whether a heart attack has occurred.

24 May 2004

Cystic Fibrosis Foundation Therapeutics awards $21 million to Vertex

Vertex Pharmaceuticals Incorporated has announced that it has expanded its drug discovery and development collaboration with Cystic Fibrosis Foundation Therapeutics, Inc. (CFFT), the nonprofit drug discovery and development affiliate of the Cystic Fibrosis Foundation.

24 May 2004

KETEK® (telithromycin) is highly active in vitro against Streptococcus pneumoniae (S. pneumoniae) isolates

Results from an ongoing surveillance study, PROTEKT US (Prospective Resistant Organism Tracking and Epidemiology of the Ketolide Telithromycin – United States) Year 2 (2001-2002), suggest that KETEK® (telithromycin) is highly active in vitro against Streptococcus pneumoniae (S. pneumoniae) isolates, including those resistant to other antimicrobial agents.

24 May 2004

in vitro News and Research

New compound that is designed to overcome Gleevec resistance

Animal bone implants that resemble natural bone

Latest findings on HIV pathogenesis at AIDS Conference in Bangkok

Natural products to be developed as anti-cancer therapeutics

Protein called Rac controls a number of biological processes and is directly implicated in several human diseases

Abnormalities observed in cloned mice help reinforce the need to continue to avoid the reproductive cloning of humans

Successes in frozen ovarian tissue technology may offer hope to women being treated for cancer

Chromosomal chaos in early embryonic development is linked to abnormalities in cytokinesis and spindle formation

Studies show new massage and physical therapy technique increased pregnancy rates in infertile women

SARS siRNA studied further to help many respiratory diseases including lung cancer

Gestational diabetes is a type of diabetes, or high blood sugar, that only pregnant women get

Conflicting views on embryonic and adult stem cells complicate research in stem cell therapeutics

Non-aspirin pain drugs may help men with recurrent prostate cancer

Studies suggest white tea help prevent staphylococcus and streptococcus infections

Stent methodologies for treating occluded arteries

More likely that older IVF mothers will suffer a pregnancy loss

Zengen announces positive results of treatment for vaginal yeast infection

New series of clinical standards to diagnose heart attacks

Cystic Fibrosis Foundation Therapeutics awards $21 million to Vertex

KETEK® (telithromycin) is highly active in vitro against Streptococcus pneumoniae (S. pneumoniae) isolates

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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