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pH comes from the term “power of Hydrogen”, or the hydrogen ion concentration present in a given solution. It helps to measure the acidity or alkalinity of a substance.

Study brings precision medicine closer to reality for diffuse large B cell lymphoma

DNA mutations are essential to the rapid development of an array of antibody-producing immune cells called B cells that collectively can recognize a vast number of specific targets.

25 May 2022

AI model can accurately identify patients at high risk of undiagnosed structural heart disease

A team of clinicians and scientists from Tempus and Geisinger have found that a new artificial intelligence model can accurately identify patients at increased risk of undiagnosed structural heart disease.

25 May 2022

Dr. Paul Brooks is CN Bio's New Chief Business Officer

CN Bio, a leading Organ-on-a-chip Company (OOC) that designs and manufactures single- and multi-organ microphysiological systems (MPS), today announced the appointment of Dr. Paul Brooks as Chief Business Officer.

From CN-Bio 25 May 2022

Biodegradable, non-ionic polymeric nanovesicles efficiently encapsulate and deliver siRNA

Small interfering RNAs, or siRNAs, hold promise to treat tumors, through their ability to specifically knock down oncogenes that promote tumor growth, without the toxicity that accompanies chemotherapy. However, the siRNAs need a delivery vehicle to protect them from degradation and clearance on their journey through the bloodstream to the cancer tumor.

25 May 2022

Insilico Medicine nominates novel preclinical candidate targeting 3CL protease for COVID-19 treatment

Insilico Medicine, a clinical-stage end-to-end artificial intelligence (AI)-driven drug discovery company, today announced its nomination of a novel preclinical candidate (PCC) targeting 3C-like (3CL) protease for the treatment of COVID-19.

24 May 2022

Stressful work environment and unemployment linked to opioid misuse among U.S. adults

Two linked studies led by UCLA Fielding School of Public Health researchers have found strong associations between drug misuse generally and opioid misuse specifically among unemployed Americans, who were found to have a 40% higher likelihood to misuse opioids than those working 35-40 hours per week.

24 May 2022

Ohio University to launch a summer program focused on diabetes research for undergraduate students

A summer program for undergraduate students who plan to pursue a graduate or medical degree related to diabetes research will be launched at Ohio University in 2023 thanks to support from a prestigious National Institutes of Health Research Education Program (R25) grant.

24 May 2022

AI tool helps doctors predict cancer risk in lung nodules seen on chest CT

An artificial intelligence (AI) tool helps doctors predict the cancer risk in lung nodules seen on CT, according to a new study published in the journal Radiology.

24 May 2022

Anti-SARS-CoV-2 antibodies persist in breast milk, even after gastrointestinal digestion

Researchers evaluate the persistence of anti-SARS-CoV-2 IgA and IgG in breast milk before and after in vitro gastrointestinal digestion.

23 May 2022

Medication, lifestyle intervention effective in preventing Type 2 diabetes, but not cardiovascular disease

A lifestyle intervention program of increased physical activity, healthy eating and aiming for weight loss of 7% or more, or taking the medication metformin were effective long-term to delay or prevent Type 2 diabetes in adults with prediabetes.

23 May 2022

Repurposed drug clofoctol blocks SARS-CoV-2 replication in mouse study

A new paper presents the results of a mouse study using the repurposed antibacterial drug clofoctol against this virus.

23 May 2022

Can human coronaviruses infect the GI tract?

Researchers review current findings on how human coronaviruses like SARS-CoV-2 might cause GI symptoms.

22 May 2022

Study reveals how ZBP1 could lead to a cytokine storm during COVID-19

Scientists from St. Jude Children's Research Hospital have shown that the innate immune sensor, ZBP1, and its associated inflammatory cell death pathway, PANoptosis, are major contributors to the negative effects of interferon treatment and high interferon levels in some COVID-19 patients.

20 May 2022

Montefiore Einstein Cancer Center partners with the Price Family Foundation to advance cancer equity

The National Cancer Institute-designated Montefiore Einstein Cancer Center (MECC) has partnered with the Price Family Foundation to fund eight research teams developing novel cancer therapies and improving cancer outcomes for historically marginalized communities in the Bronx.

20 May 2022

Research provides new insight into how Crimean-Congo hemorrhagic fever virus causes disease

Army scientists determined that the body's own natural immune response contributes to disease severity in mice infected with Crimean-Congo hemorrhagic fever virus (CCHFV), which causes a widespread tick-borne viral infection in humans.

20 May 2022

New training scheme for convolutional neural networks automates cell segmentation and counting

The use of machine learning to perform blood cell counts for diagnosis of disease instead of expensive and often less accurate cell analyzer machines has nevertheless been very labor-intensive as it takes an enormous amount of manual annotation work by humans in the training of the machine learning model.

20 May 2022

Researchers discover how one type of T cell creates functionally distinct, but genetically identical daughter cells

Scientists at St. Jude Children's Research Hospital have solved an immunology puzzle. A CD8+ T cell can have two functionally distinct daughter cells after it divides, despite the cells being genetically identical.

20 May 2022

UNC-Chapel Hill secures $65 million NIH grant for establishing Antiviral Drug Discovery Center

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health awarded the UNC Gillings School of Global Public Health a $65 million grant establishing an Antiviral Drug Discovery Center to develop oral antivirals that can combat pandemic-level viruses like COVID-19.

20 May 2022

Novel brain-permeable Cdk5 inhibitor alters neurobehavior in mice

James Bibb, Ph.D., and colleagues have described a novel preclinical drug that could have the potential to combat depression, brain injury and diseases that impair cognition. The drug, which notably is brain-permeable, acts to inhibit the kinase enzyme Cdk5.

20 May 2022

‘Sting’ protein’s response to clean up damaged brain cells may accelerate Parkinson’s disease progression

In studies with mouse and human tissue, as well as live mice, Johns Hopkins Medicine researchers report that a snag in the normal process of cleaning up broken DNA in brain cells may hasten the progression of Parkinson's disease.

19 May 2022

pH News and Research

Further Reading

Study brings precision medicine closer to reality for diffuse large B cell lymphoma

AI model can accurately identify patients at high risk of undiagnosed structural heart disease

Dr. Paul Brooks is CN Bio's New Chief Business Officer

Biodegradable, non-ionic polymeric nanovesicles efficiently encapsulate and deliver siRNA

Insilico Medicine nominates novel preclinical candidate targeting 3CL protease for COVID-19 treatment

Stressful work environment and unemployment linked to opioid misuse among U.S. adults

Ohio University to launch a summer program focused on diabetes research for undergraduate students

AI tool helps doctors predict cancer risk in lung nodules seen on chest CT

Anti-SARS-CoV-2 antibodies persist in breast milk, even after gastrointestinal digestion

Medication, lifestyle intervention effective in preventing Type 2 diabetes, but not cardiovascular disease

Repurposed drug clofoctol blocks SARS-CoV-2 replication in mouse study

Can human coronaviruses infect the GI tract?

Study reveals how ZBP1 could lead to a cytokine storm during COVID-19

Montefiore Einstein Cancer Center partners with the Price Family Foundation to advance cancer equity

Research provides new insight into how Crimean-Congo hemorrhagic fever virus causes disease

New training scheme for convolutional neural networks automates cell segmentation and counting

Researchers discover how one type of T cell creates functionally distinct, but genetically identical daughter cells

UNC-Chapel Hill secures $65 million NIH grant for establishing Antiviral Drug Discovery Center

Novel brain-permeable Cdk5 inhibitor alters neurobehavior in mice

‘Sting’ protein’s response to clean up damaged brain cells may accelerate Parkinson’s disease progression

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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