The Thermo Scientific NanoDrop™ Eight UV-Vis Spectrophotometer increases the success of analyses with effective characterization of the quantity and quality of eight samples at a time. The device is well-suited for pharma/biotech and academic researchers measuring a greater number of protein and nucleic acid samples.

With the NanoDrop Eight Spectrophotometer, one can measure eight samples simultaneously in less than 20 seconds. The built-in Thermo Scientific™ Acclaro™ Sample Intelligence technology enables the identification of contaminants in the sample and informs the original sample concentration. Optional software enables users to easily comply with 21 CFR Part 11 regulations.

Product overview

NanoDrop Eight is a multichannel spectrophotometer that allows the easy quantification of samples with confidence. It's a state-of-the-art microvolume UV-Vis spectrophotometer with enhanced hardware and the finest software features from the Thermo Scientific™ NanoDrop™ One/OneC Spectrophotometer.

Acclaro Contaminant Identification ensures samples are high quality

The NanoDrop Eight Spectrophotometer measures the actual concentration of protein or nucleic acid without the interference or the effects of sample contaminants. Knowledge of the sample composition helps downstream experiments to proceed right the first time.

  • Identifying contaminants — The spectrophotometer identifies ordinary contaminants found in protein and nucleic acid samples that can hinder downstream reactions or falsely elevate calculated concentrations
  • Corrected calculations — The device applies chemometric algorithms to ascertain the actual concentration of the analyte minus the contaminant
  • Differentiating DNA from RNA — The algorithms can pinpoint mammalian RNA contaminating a dsDNA sample or mammalian dsDNA contaminating an RNA sample

NanoDrop Eight Spectrophotometer enhancements

The NanoDrop Eight instrument provides many advantages beyond its predecessor, the NanoDrop 8000 Spectrophotometer:

  • Broader dynamic range — To measure higher concentration samples without dilution — up to 145 mg/mL IgG or 10,000 ng/μL dsDNA.
  • Ergonomic ambidextrous pipetting — The pedestal array is aligned perpendicular to the front of the instrument to provide a natural pipetting motion for users. The pipette guide is magnetic and adjustable from side to side, enabling right- and left-handed users to swiftly, comfortably dispense samples.
  • Auto-Measure and Auto-Blank functions — These functions enable streamlining of multi-sample processing with immediate measurements that take place when the pedestal arm is down. With a single tap of the screen, these functions can be turned ON or OFF.
  • Automated exports for LIMS — It sets a directory for data to be exported automatically. The LIMS software sweeps the folder to pull in NanoDrop Eight instrument data for archiving.

Regulatory compliance made easy

The optional Thermo Scientific™ SciVault™ Software helps the laboratory comply with US FDA data regulations at every step.

  • Compliance with US FDA 21 CFR Part 11 Regulation — Regulates user account access, reviews audit logs, and applies digital signatures
  • Streamlined — SciVault Software integrates seamlessly into the NanoDrop Eight Software user interface
  • Network multiple instruments — Install SciVault Software on a central computer to control privileges and view audit logs across multiple NanoDrop Eight instruments in various laboratories
  • Validating systems — IQ/OQ documents and services are available to confirm that the instrument is running within the manufacturer’s specifications

Software updates to make time more productive

  • Ready to start — The NanoDrop Eight Software comes hard-coded with the widely employed measurement applications including RNA, dsDNA, Protein A280, and UV-Vis
  • Constantly improving — User input keeps NanoDrop Software continuously progressing with updates that provide enhanced capabilities and efficiencies in the laboratory
NanoDrop™ Eight Spectrophotometer.

NanoDrop Eight Spectrophotometer. Image Credit: Thermo Fisher Scientific – Materials & Structural Analysis

NanoDrop™ Eight Spectrophotometer.

NanoDrop Eight Spectrophotometer. Image Credit: Thermo Fisher Scientific – Materials & Structural Analysis

NanoDrop™ Eight Spectrophotometer.

NanoDrop Eight Spectrophotometer. Image Credit: Thermo Fisher Scientific – Materials & Structural Analysis

NanoDrop™ Eight Spectrophotometer.

NanoDrop Eight Spectrophotometer. Image Credit: Thermo Fisher Scientific – Materials & Structural Analysis

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