Gene News and Research

Latest Gene News and Research

Study reports that depleting gut bacteria in mice with genetic risk for AD reduces neuropathology in a sex-dependent manner

Researchers highlight recent research investigating whether gut microbiota regulates tau pathology and tau-mediated neurodegeneration in an ApoE isoform–dependent manner.

21 Feb 2023

Researchers report the circulation of a novel MERS-like coronavirus in Malayan pangolins

Researchers reported the circulation of a novel MERS-like coronavirus among Malayan pangolins, Manis javanica HKU4-associated CoV (MjHKU4r-CoV).

21 Feb 2023

Researchers provide a framework for unifying and categorizing neurodegenerative diseases based on eight hallmarks

Researchers presented eight hallmarks of neurodegenerative diseases (NDDs), their in vivo biomarkers, and interactions to help categorize NDDs and specify patients within a specific NDD.

21 Feb 2023

First fully human ovarian organoids provide insights about female reproductive health and disease

Despite the fact that we all start out as an egg cell in one of our mother's ovaries, these human reproductive organs are surprisingly under-studied.

21 Feb 2023

HKU research advances understanding of the fundamental biological processes of gene regulation

A research team from the University of Hong Kong led by Professor Xiang David Li from the Department of Chemistry in collaboration with Dr Yuanliang Zhai from the HKU School of Biological Sciences and Dr Jason Wing Hon Wong and Dr Xiucong Bao from the HKU School of Biomedical Sciences recently made a key breakthrough in understanding how genetic information encoded in our DNA is 'read' and why errors in 'reading' such information can often lead to developmental defects or cancers.

20 Feb 2023

395 genes found to be differently expressed in people with type 2 diabetes

Researchers have identified 395 genes that are differently expressed in people with type 2 diabetes. One of the genes proved to be very strongly associated with impaired insulin secretion.

20 Feb 2023

Utilizing CRISPR to discover new therapy options for COPD

In this interview, we speak to Ceri Wiggins, a Director at AstraZeneca, about the many applications of CRISPR and its role in discovering new COPD therapies.

From Society for Laboratory Automation and Screening (SLAS) 20 Feb 2023

After a previous BA.1 infection, Omicron BA.4/5 infection is more likely than BA.2

In a recent study published in the journal Eurosurveillance, researchers investigated whether prior severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and/or coronavirus disease 2019 (COVID-19) vaccination protected against SARS-CoV-2 Omicron variant of concern (VOC) BA.4/5 sub-VOC or BA.2 sub-VOC infections.

19 Feb 2023

Genome editing prevents hypertrophic cardiomyopathy in mice

In a recent study published in the journal PLoS Digital Health, researchers pursued one-time cures for hypertrophic cardiomyopathy (HCM). They used a previously constructed murine model of HCM, designated as R403Q-129SvEv, to evaluate two different genetic therapies, as follows:

19 Feb 2023

Gut dysbiosis and sepsis susceptibility among pregnant women

Researchers describe the role of gut dysbiosis during pregnancy in promoting excessive macrophage pyroptosis, which increases vulnerability to sepsis.

19 Feb 2023

UTHSC researchers secure $308,000 grant from Department of Defense for dementia study

Repeated traumatic brain injuries (TBI) in soldiers and military personnel can cause behavioral, neurological, and cognitive effects and lead to dementia.

19 Feb 2023

Toxic protein may be the cause of muscular dystrophy and arhinia

Balancing care responsibilities with paid work provides working caregivers with emotional benefits

19 Feb 2023

Researchers use the drug fasudil to reverse two key symptoms of schizophrenia

A team from Nagoya University in Japan used the drug fasudil to reverse two common symptoms associated with schizophrenia: reduced density of pyramidal neurons and cognitive dysfunction associated with methamphetamine treatment.

17 Feb 2023

Exploring the potential of betalain-engineered vegetables in conferring anti-inflammatory properties

Metabolic engineering is a field of plant biotechnology that seeks to genetically modify plant metabolic pathways to generate plant varieties with improved health benefits.

17 Feb 2023

Scientists discover how a "poisoned" form of protein could spur cancer formation

Scientists at Scripps Research, with collaborators in Japan, have discovered how a "poisoned" form of a protein could set off a cascade of events that encourage the growth of some cancers.

17 Feb 2023

California requires hospitals to turn to a patient’s next of kin, closing a longtime loophole

About four years ago, Dr. Gene Dorio sat on the ethics committee of a Southern California hospital whose administrators insisted they could decide whether to disconnect a ventilator from an unconscious patient — even though the man's wife and adult children wanted to continue life support.

17 Feb 2023

Gene News and Research

Latest Gene News and Research

Study reports that depleting gut bacteria in mice with genetic risk for AD reduces neuropathology in a sex-dependent manner

Researchers report the circulation of a novel MERS-like coronavirus in Malayan pangolins

Researchers provide a framework for unifying and categorizing neurodegenerative diseases based on eight hallmarks

First fully human ovarian organoids provide insights about female reproductive health and disease

HKU research advances understanding of the fundamental biological processes of gene regulation

395 genes found to be differently expressed in people with type 2 diabetes

Utilizing CRISPR to discover new therapy options for COPD

After a previous BA.1 infection, Omicron BA.4/5 infection is more likely than BA.2

Genome editing prevents hypertrophic cardiomyopathy in mice

Gut dysbiosis and sepsis susceptibility among pregnant women

UTHSC researchers secure $308,000 grant from Department of Defense for dementia study

Toxic protein may be the cause of muscular dystrophy and arhinia

Researchers use the drug fasudil to reverse two key symptoms of schizophrenia

Exploring the potential of betalain-engineered vegetables in conferring anti-inflammatory properties

Scientists discover how a "poisoned" form of protein could spur cancer formation

California requires hospitals to turn to a patient’s next of kin, closing a longtime loophole

A new trial to assess if butyrate can prevent colon cancer

Similar genes may lead to different patterns of fat distribution in women

Genes encoding T cell receptors vary greatly between persons and populations, study reveals

Repurposing or improving drugs for spinocerebellar ataxia type 5

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research