Gene News and Research

Latest Gene News and Research

Variations in low-complexity regions in monkeypox genome found to impact virus transmissibility

In a new study, researchers investigated whether low-complexity regions (LCRs) were more accountable for the current 2022 IIb clade monkeypox (MPX) virus (MPXV) outbreak rather than single-nucleotide polymorphisms (SNPs).

24 Oct 2022

Investigating the evidence of synthetic origins of SARS-CoV-2

Researchers investigated whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) originated naturally from an animal-to-human spillover or synthetically during coronavirus research experiments.

24 Oct 2022

Clinical trial confirms the safety, efficacy of shortened radiation therapy for high-risk prostate cancer patients

A new randomized study confirms that men with high-risk prostate cancer can be treated with five versus eight weeks of radiation therapy.

24 Oct 2022

Celebrating the Alderley Park Grand Opening

HQ Plasmid Center of Excellence based at UK life science hotspot now open for business.

From Charles Rivers Laboratories Cell and Gene Therapy 24 Oct 2022

Dog ownership during infancy might attenuate the risk of persistent wheezing

In a new study, researchers examined the gene-environment (GxE) interactions between pet ownership in infancy and the 17q12-21 (asthma-risk) locus concerning wheezing.

24 Oct 2022

Combining host gene expression profiling and metagenomic pathogen detection from plasma nucleic acid enables accurate sepsis diagnosis

Researchers developed integrated host-microbe plasma metagenomics to facilitate sepsis diagnosis.

24 Oct 2022

The Black Death may have influenced the evolution of genes involved in immune responses against pathogens

Researchers gathered empirical evidence that past pandemics due to infectious pathogens shaped the present-day susceptibility of humans to diseases, such as autoimmune diseases.

24 Oct 2022

A novel approach for viral genomic surveillance

In a recent study posted to the bioRxiv* preprint server, researchers in the United States explored a novel technique to improve representation in viral genomic surveillance.

24 Oct 2022

Research suggests that ORF6 is a major SARS-CoV-2 innate immune antagonist

In a recent study posted to the bioRxiv* server, researchers in the United States demonstrated how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) open reading frame 6 (ORF6) protein contributes to viral pathogenesis and modulates the host's immune responses.

23 Oct 2022

Overview of the roles of neutrophils in systemic autoimmune and autoinflammatory diseases

Researchers assess the role of neutrophil extracellular traps (NETs) in systemic autoimmune and autoinflammatory disorders.

23 Oct 2022

Booster vaccinations in the elderly lead to impaired neutralization of SARS-CoV-2 and atypical B cells

Researchers examine neutralizing antibody responses against SARS-CoV-2 in elderly individuals who received one mRNA booster dose.

23 Oct 2022

Biochemical and structural evidence demonstrates Omicron mutations are better adapted to mouse ACE2 than to human ACE2

Researchers demonstrated the structural basis of how the receptor-binding domain nested Omicron mutations have adapted to mouse angiotensin-converting enzyme 2 rather than human ACE2.

22 Oct 2022

Study indicates that the major determinants of SARS-CoV-2 pathogenicity reside outside of the spike protein

Researchers at Boston University made a chimeric recombinant SARS-CoV-2 encoding the spike glycoprotein gene of Omicron in the backbone of an ancestral SARS-CoV-2 isolate.

22 Oct 2022

TANGO2 plays a role in heme homeostasis, research reveals

Heme, the iron-holding molecule that gives blood its red color, is essential for life. Yet, ironically, it can be quite toxic if not properly handled. In fact, numerous diseases – from various cancers to cardiovascular diseases – are associated with defects in heme homeostasis.

21 Oct 2022

Butterfly wing pattern ground plan is manipulated by non-coding regulatory DNA, study says

Butterfly wing patterns have a basic plan to them, which is manipulated by non-coding regulatory DNA to create the diversity of wings seen in different species, according to new research.

21 Oct 2022

Scientists discover molecular link between lung tumor growth and disrupted circadian rhythms

Scientists discovered an important molecular link between lung tumor growth and disrupted circadian rhythms, according to a new paper co-authored by a University of Rochester Wilmot Cancer Institute investigator and led by the Scripps Research Institute in California.

21 Oct 2022

Study reveals TBX20 as a vital regulator of direct human cardiac reprogramming

Mammalian hearts have almost no ability to grow new heart muscle cells, called cardiomyocytes, after birth. Thus, dead tissue after an adult heart attack is not repaired with new cardiomyocytes.

21 Oct 2022

Study reconsiders the recommended age for screening women with family history of breast cancer

A new study released in the American Cancer Society journal Cancer reconsiders guidelines for when to start screening with mammograms if a woman has a mother, sister, or daughter who was diagnosed with breast cancer.

21 Oct 2022

Building DNA-based synthetic condensates with programmable compositions and functionalities

Recent studies have shown that liquid-liquid phase separation – akin to how oil droplets form in water – leads to formation of diverse types of membraneless organelles, such as stress granules and nucleoli, in living cells.

21 Oct 2022

Surprising discovery in people of Polynesian ancestry offers clues to genetic underpinnings of high cholesterol

The discovery of a genetic variant that is relatively common among people of Polynesian ancestry, but incredibly rare in most other populations, is giving clues to the genetic underpinnings of high cholesterol in all people, according to new research led by University of Pittsburgh School of Public Health geneticists in partnership with several other groups, including the University of Otago and the Samoan health research community.

21 Oct 2022

Gene News and Research

Latest Gene News and Research

Variations in low-complexity regions in monkeypox genome found to impact virus transmissibility

Investigating the evidence of synthetic origins of SARS-CoV-2

Clinical trial confirms the safety, efficacy of shortened radiation therapy for high-risk prostate cancer patients

Celebrating the Alderley Park Grand Opening

Dog ownership during infancy might attenuate the risk of persistent wheezing

Combining host gene expression profiling and metagenomic pathogen detection from plasma nucleic acid enables accurate sepsis diagnosis

The Black Death may have influenced the evolution of genes involved in immune responses against pathogens

A novel approach for viral genomic surveillance

Research suggests that ORF6 is a major SARS-CoV-2 innate immune antagonist

Overview of the roles of neutrophils in systemic autoimmune and autoinflammatory diseases

Booster vaccinations in the elderly lead to impaired neutralization of SARS-CoV-2 and atypical B cells

Biochemical and structural evidence demonstrates Omicron mutations are better adapted to mouse ACE2 than to human ACE2

Study indicates that the major determinants of SARS-CoV-2 pathogenicity reside outside of the spike protein

TANGO2 plays a role in heme homeostasis, research reveals

Butterfly wing pattern ground plan is manipulated by non-coding regulatory DNA, study says

Scientists discover molecular link between lung tumor growth and disrupted circadian rhythms

Study reveals TBX20 as a vital regulator of direct human cardiac reprogramming

Study reconsiders the recommended age for screening women with family history of breast cancer

Building DNA-based synthetic condensates with programmable compositions and functionalities

Surprising discovery in people of Polynesian ancestry offers clues to genetic underpinnings of high cholesterol

eBook: Using iPSCs models for human disease research and drug discovery eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging