Gene

A gene is a unit of heredity in a living organism. It normally resides on a stretch of DNA that codes for a type of protein or for an RNA chain that has a function in the organism. All living things depend on genes, as they specify all proteins and functional RNA chains.

What are Genes?

Deoxyribonucleic acid (DNA) is the chemical information database that carries the complete set of instructions for the cell as to the nature of the proteins produced by it, its life span, maturity, function and death. Genes are the working subunits of DNA. Each gene contains a particular set of instructions, usually coding for a particular protein or for a particular function.

Gene Editing Techniques: ZFNs, TALENs or CRISPR?

Tumor Suppressor Genes

Functions of BRCA1/2 Gene Products

Gene Knockout versus Knockdown

Conditional Gene Knockout Techniques

What is SATI Gene Editing?

Genetics and Gene Expression

Gene History

What are Homeobox Genes?

Ras Genes and Cancer

See more featured articles »

Horizontal Gene Transfer

Genetic Inheritance

Gene Knockin

Genes that Control Pluripotency

Horizontal Gene Transfer and Antibiotic Resistance

The Latest Advances in Cell and Gene Therapy

Latest Gene News and Research

Fondazione Telethon achieves milestone with Waskyra approval for Wiskott-Aldrich Syndrome

Fondazione Telethon announces the positive opinion issued by the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) recommending marketing authorization in the European Union for Waskyra, an ex vivo gene therapy for Wiskott-Aldrich Syndrome (WAS), a rare and life-threatening primary immunodeficiency.

14 Nov 2025

DeepTarget: A new tool for drug repurposing in oncology

One person's side effect could be another person's treatment if we expand our perspective on small molecule drug targets, according to a new study published November 5, 2025, in npj Precision Oncology.

14 Nov 2025

New insights into periodontitis reveal gender-specific inflammatory mechanisms

A study out of the University of North Carolina at Chapel Hill has unveiled new insights into the inflammatory processes behind periodontitis, a common and debilitating gum disease. Research conducted by UNC Adams School of Dentistry's Julie Marchesan, DDS, PhD, and UNC School of Medicine's Jenny Y. Ting, PhD, found that a part of the immune system called the inflammasome plays a key role in disease development, and that blocking this system prevents bone resorption only in males.

14 Nov 2025

Subtle changes in the composition of short tandem repeats may shape disease risk

Scientists at The Hospital for Sick Children (SickKids) have revealed a previously overlooked layer of genetic variation that could help explain why people experience disease differently, and why some treatments work better for certain populations.

14 Nov 2025

New molecular test revolutionizes fungal infection diagnosis

Certain serious fungal infections occur in regions of the United States with specific environments and are often tied to soil exposure.

14 Nov 2025

Terasaki Institute and Caltech join forces on groundbreaking embryo formation study

The Terasaki Institute for Biomedical Innovation (TIBI) is pleased to announce its collaboration with the California Institute of Technology (Caltech) on a newly awarded $2.8 million Discovery Stage Research (DISC0) grant from the California Institute for Regenerative Medicine (CIRM).

14 Nov 2025

Hypertension may induce early gene expression changes in brain cells

Hypertension impairs blood vessels, neurons and white matter in the brain well before the condition causes a measurable rise in blood pressure, according to a new preclinical study from Weill Cornell Medicine investigators.

14 Nov 2025

Exploring m6A RNA modification as a therapeutic target in cardiovascular disorders

Emerging research highlights the transformative potential of m6A RNA modification in the diagnosis and treatment of cardiovascular diseases (CVDs).

14 Nov 2025

Transforming colorectal cancer research with patient-derived xenograft models

Patient-derived xenograft (PDX) models are emerging as a transformative tool in colorectal cancer (CRC) research, offering unparalleled insights into tumor biology, drug resistance, and personalized treatment approaches.

14 Nov 2025

Indero announces breakthrough method for early-phase evaluation of topical drugs using quantitative gene expression

Indero is proud to announce the successful completion of an internally funded study that introduces a novel approach to evaluating topical new chemical entities (NCE) in early-phase clinical research.

14 Nov 2025

Tiny antibiotic traces found to greatly accelerate resistance spread

Antibiotic resistance is widely recognized as one of the most urgent public health challenges of the twenty first century.

13 Nov 2025

Scientists reveal how prolonged UV exposure weakens cellular defense against skin cancer

Sunlight is vital for human health as it helps the body produce essential nutrients, such as vitamin D. However, too much sun exposure can significantly increase the risk of skin cancer.

13 Nov 2025

Scientists map the genetic control system behind FOXP3 in immune cells

The immune system faces a delicate balancing act: it must be aggressive enough to fight infections and cancer, yet restrained enough to avoid attacking the body's own tissues.

13 Nov 2025

New approach revives DNA from historic medical tissues

Research institutions around the world house valuable genetic information that could help unlock countless medical mysteries. However, because DNA degrades over time, it is difficult for researchers to analyze DNA samples older than 20 years using conventional analytical approaches.

13 Nov 2025

Pig kidney transplant breakthrough uncovers immune rejection secrets

Researchers have uncovered and then overcome an obstacle that has led to the failure of pioneering efforts in xenotransplantation, in which an animal kidney is transplanted into a human.

13 Nov 2025

Single-cell study reveals how HPV shapes immune landscape in penile cancer

Although penile cancer represents less than 1% of male malignancies, it carries substantial physical and psychological burden, with a five-year survival rate near 50%.

13 Nov 2025

Celleo Biotech uses INTEGRA's PIPETBOY GENIUS to improve reproducibility and efficiency

Celleo Biotech is using the PIPETBOY GENIUS serological pipet controller from INTEGRA Biosciences to streamline the development and manufacturing of novel cell and gene therapies.

From INTEGRA Biosciences 13 Nov 2025

Cellarity's AI model predicts drug-induced liver injury

Cellarity, a clinical-stage biotechnology company developing Cell State-Correcting therapies through integrated multi-omics and AI modeling, today announced the publication of a seminal manuscript in Nature Communications, which describes a novel framework for the prediction and characterization of drug-induced liver injury (DILI), along with open-source posting of the model and validation data.

13 Nov 2025

Innovative research reveals FGD3 as a key player in breast cancer cell death

A naturally occurring protein that tends to be expressed at higher levels in breast cancer cells boosts the effectiveness of some anticancer agents, including doxorubicin, one of the most widely used chemotherapies, and a preclinical drug known as ErSO, researchers report.

13 Nov 2025

Stanford scientists discover unexpected cancer resistance in aged mice

Old laboratory mice develop substantially fewer and less-aggressive lung tumors than younger animals in a new study led by Stanford University researchers.

12 Nov 2025