Gene

A gene is a unit of heredity in a living organism. It normally resides on a stretch of DNA that codes for a type of protein or for an RNA chain that has a function in the organism. All living things depend on genes, as they specify all proteins and functional RNA chains.

What are Genes?

Deoxyribonucleic acid (DNA) is the chemical information database that carries the complete set of instructions for the cell as to the nature of the proteins produced by it, its life span, maturity, function and death. Genes are the working subunits of DNA. Each gene contains a particular set of instructions, usually coding for a particular protein or for a particular function.

Conditional Gene Knockout Techniques

What is SATI Gene Editing?

What are Homeobox Genes?

Ras Genes and Cancer

Tumor Suppressor Genes

Genetic Inheritance

Horizontal Gene Transfer and Antibiotic Resistance

Genes that Control Pluripotency

Horizontal Gene Transfer

What are Homeobox Genes?

Genetics and Gene Expression

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Functions of BRCA1/2 Gene Products

Gene Knockin

Gene History

Gene Knockout versus Knockdown

The Latest Advances in Cell and Gene Therapy

Gene Editing Techniques: ZFNs, TALENs or CRISPR?

Latest Gene News and Research

AI-based methods help uncover hidden roots of tumor metastasis

A cancerous tumor is not a single enemy. It is made up of many different cell populations that can behave in very different ways.

12 Aug 2026

AI-augmented analysis sheds new light on Crohn's disease complications

Scientists have combined Artificial Intelligence (AI), genetics and gut microbiome analysis to shed new light on one of the most serious complications of Crohn's disease: intestinal fibrosis, the irreversible scarring of the bowel that often leads to surgery.

12 Aug 2026

Mitochondrial gene RTN4IP1 drives triple-negative breast cancer metastasis

Triple-negative breast cancer accounts for approximately 15% of all breast cancer cases. It is characterized by the absence of estrogen receptor, progesterone receptor, and HER2 expression, rendering it insensitive to conventional endocrine and targeted therapies.

12 Aug 2026

Aging clock analysis identifies key genes in opioid dependence

A new research paper was published in Volume 18 of Aging on July 27, 2026, titled "Transcriptomic aging clock analysis identifies key genes in opioid dependence."

12 Aug 2026

Targeting single gene reverses developmental deficits in adult mice

Some of the symptoms of neurodevelopmental disorders (NDDs) such as autism spectrum disorder and epilepsy may result from dysfunction of certain neurons in the brain and their ability to change their properties in response to experiences-a process called experience-dependent plasticity.

12 Aug 2026

Molecular mapping reveals hidden cellular programs in heart transplant rejection

A new study that explores gene expression during heart transplant rejection marks a step forward for precision medicine approaches to treat organ rejection.

12 Aug 2026

Machine learning uses gene neighborhoods to identify harmful poultry bacteria

When it comes to identifying harmful bacteria, it helps to look at the company their genes keep.

12 Aug 2026

Cannabis compounds may weaken glioblastoma response to chemotherapy and radiation

Several cannabinoids reduced chemotherapy- and radiation-induced apoptosis in glioblastoma cell models, with effects linked to reduced apoptotic priming, increased pro-survival signaling, and G1 cell-cycle arrest. The findings raise concern that cannabinoid exposure could interfere with some cancer treatments, although the results are limited to laboratory models and require in vivo and clinical validation.

12 Aug 2026

Senescent brain immune cells secrete protein linked to cognitive decline

Brain-resident immune cells that have reached an old-age state called "senescence" secrete a protein that causes dysfunction in other brain cells, according to a study led by investigators at Weill Cornell Medicine.

11 Aug 2026

Huge philanthropic grant funds pioneering stem cell-based heart attack therapy

In a landmark moment for both the treatment of heart disease and philanthropic support, The Marcus Foundation has awarded the head of USC Stem Cell Center, Chuck Murry, MD, PhD, $28.7 million to advance a clinical trial testing a stem cell-based therapy designed to regenerate damaged tissue after a heart attack.

11 Aug 2026

Shared cellular pathway drives neurodegeneration in rare childhood dementia and Alzheimer’s

Researchers at University of California San Diego and their colleagues have identified a key cellular pathway that drives brain degeneration in both a rare childhood disorder and the far more common Alzheimer's disease.

11 Aug 2026

New computational tool identifies hidden genes driving asthma

Researchers at Columbia University Mailman School of Public Health, in collaboration with investigators at the University of Chicago, have developed a new computational framework that helps scientists identify genes that play central roles in diseases such as asthma but are often overlooked by existing genetic analysis methods.

11 Aug 2026

Scientists identify parasite-specific protein linked to chronic Toxoplasma infections

Toxoplasma gondii, or Toxoplasma, is a parasite that infects hundreds of millions of people around the world.

11 Aug 2026

Folic acid relies on vitamin A pathway to prevent birth defects

For decades, we've known that folic acid can help prevent serious birth defects of the brain and spinal cord, but we haven't fully understood how it does it.

11 Aug 2026

Researchers identify molecular targets to treat painful nerve neuromas

Human peripheral nerves have a remarkable ability to regenerate after damage. However, when re-growing axons fail to meet their target organ, they can transform into painful neuromas.

11 Aug 2026

Early-life stress rewires brain epigenetics to heighten sensitivity to future stress

. Early-life stress increased SETD7 and H3K4me1 in the ventral tegmental area of mice, creating an epigenetically primed state that heightened later transcriptional, neuronal, and behavioral responses to stress. Reducing Setd7 during development lowered H3K4me1 and weakened these stress-sensitizing effects, identifying a mechanism that may help explain how early adversity leaves lasting biological effects.

11 Aug 2026

Broken String Biosciences launches BaseMap ABE to enable genome-wide off-target characterization in base editing therapeutic development

Broken String Biosciences, a biotechnology company enabling gene editing teams to accelerate development of safer, more effective genetic medicines, today announced the launch of BaseMap™ ABE. Built on the Company\'s INDUCE-seq® technology, BaseMap ABE extends the platform\'s capabilities to support adenine base editing (ABE) applications.

From Broken String Biosciences 10 Aug 2026

H5N1 infections remain rare among workers exposed to infected birds

A two-year cohort study of 428 people exposed to H5N1-infected birds in England found fewer than 1% met criteria for infection, with no severe disease or secondary human transmission. The findings support continued PPE use, biosecurity, and targeted surveillance while highlighting challenges around occupational exposure, mucosal contamination, and pandemic preparedness.

10 Aug 2026