Gene News and Research

Latest Gene News and Research

Eldelumab and Fenofibrate show potential for COVID-19

In a new study posted to the medRxiv* preprint server, researchers from the University of Pittsburgh and Barrow Neurological Institute report the results of their analysis of several RNA-Seq studies and used computational approaches to discover potential drugs against COVID-19.

10 Jun 2021

Research clarifies neuron-specific DNA methylation changes and characteristics in bipolar disorder

A research collaboration based in Kumamoto University, Japan has revealed the DNA methylation status of gene transcriptional regulatory regions in the frontal lobes of patients with bipolar disorder (BD).

9 Jun 2021

SARS-CoV-2 enzyme inhibitors among drugs screened for repurposing

A new bioRxiv* preprint describes the identification of some promising pharmaceutical compounds that could be developed as antiviral drugs against COVID-19.

9 Jun 2021

Study reveals how high fat diets can cause intestinal and colon cancer

For decades, physicians and dieticians have urged people to limit their intake of high fat foods, citing links to poor health outcomes and some of the leading causes of death in the U.S., such as diabetes, heart disease and cancer.

9 Jun 2021

New cell-penetrating peptide may protect against life-threatening microbial inflammation

A cell-penetrating peptide developed by researchers at Vanderbilt University Medical Center can prevent, in an animal model, the often-fatal septic shock that can result from bacterial and viral infections.

9 Jun 2021

Researchers identify a common mechanism underlying diverse brain disorders

Researchers at Vanderbilt University Medical Center have identified a common mechanism underlying a spectrum of epilepsy syndromes and neurodevelopmental disorders, including autism, that are caused by variations in a gene encoding a vital transporter protein in the brain.

9 Jun 2021

DNA on-off switches for SARS-CoV-2 host receptor as potential therapeutic targets

Researchers in the United States and Canada have identified DNA on/off “switches” within the angiotensin-converting enzyme 2 (ACE2) gene that may control the expression of this host cell receptor before, during and after infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

9 Jun 2021

Smoking and vaping increase ACE2 levels and virus spike binding in airway epithelium

A new bioRxiv preprint attempts to make some sense of why certain people experience more severe forms of COVID-19 as compared to others by pointing to the increase in virus binding that occurs in the presence of smoking or vaping.

9 Jun 2021

Researchers review the therapeutic potential of resveratrol nasal formulations in COVID-19

In a recently published article in the journal Frontiers in Immunology, scientists have reviewed the existing literature on antiviral and anti-inflammatory efficacy of resveratrol-based inhaled formulations in preventing SARS-CoV-2 infection and reducing COVID-19 severity.

9 Jun 2021

Researchers identify novel gene that controls sleep/wake cycle in mice

That internal nagging feeling that drives you to seek sleep at night and wake in the morning to eat, work, and play, is, it turns out, genetic, and it's not just in people.

9 Jun 2021

Researchers map potential toxicity of lanthanide metals used in medicine

Lanthanides are rare-earth heavy metals with useful magnetic properties and a knack for emitting light. Researchers had long assumed that lanthanides' toxicity risk was low and therefore safe to implement in a number of high-tech breakthroughs we now take for granted: from OLEDs (organic light-emitting displays)¬¬ to medical MRIs and even hybrid vehicles.

9 Jun 2021

Researchers uncover new gene mutation responsible for cerebral cavernous malformation

Researchers from the Hong Kong University of Science and Technology and Beijing Tiantan Hospital have recently uncovered a new gene mutation responsible for the non-familial patients of cerebral cavernous malformation (CCM) - a brain vascular disorder which inflicted about 10~30 million people in the world.

8 Jun 2021

Researchers find new insight on the link between a gene and congenital heart disease

New insight on the link between a gene called SORBS2 and congenital heart disease has been published today in eLife, with findings that may help explain the cause of the disease in some patients.

8 Jun 2021

How SARS-CoV-2 variant B.1.1.7 adapted to evade innate immunity

Researchers in the United States and the UK have conducted a study showing how the B.1.1.7 (Alpha) lineage of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) adapted to suppress host innate immune responses in lung epithelial cells.

8 Jun 2021

Could the intranasal route be an alternate avenue of COVID-19 vaccination?

A new study has been published in the journal Vaccines that summarizes the history of vaccines, reviews the current progress in COVID-19 vaccine technology, and discusses the status of intranasal COVID-19 vaccines as a potential pathway to immunization.

8 Jun 2021

Researchers review environmental risk assessments for recombinant COVID-19 viral vector vaccines

In a recent review, published in the journal Vaccines, researchers in Belgium look at the recombinant viral vector-vaccine candidates that are primarily against SARS-CoV-2 still in development and discuss their features from an environmental risk point of view.

8 Jun 2021

New study could help guide oncologists in selecting the best treatment for kidney cancers

Not all kidney cancers behave the same, with wildly different responses to immunotherapy or other treatments – and wildly different outcomes for patients as a result.

8 Jun 2021

New chip mimicking bovine endometrium could play key role in cattle’s pregnancy success

To investigate factors that can jeopardize pregnancy success in cattle, researchers at the University of São Paulo (USP) in Brazil used a kind of chip to mimic the environment of the endometrium, the tissue that lines the inside of the uterus.

8 Jun 2021

Bacteria causing urinary tract infections can originate in meat-production chain

In young women, Staphylococcus saprophyticus is a main cause of urinary tract infections (UTI), reaching 20% prevalence. Understanding the epidemiology of this microorganism can help identify its origin, distribution, causes, and risk factors.

8 Jun 2021

New generative model has wide implications in developmental biology, regenerative medicine

Various forms of complex multicellular organisms have evolved on Earth, ranging from simple Volvox carterii which possess only 2 cell- types to us humans with more than 200 cell types. All originate from a single celled zygote, and their developmental processes depend on switch-like gene regulation.

8 Jun 2021

Gene News and Research

Latest Gene News and Research

Eldelumab and Fenofibrate show potential for COVID-19

Research clarifies neuron-specific DNA methylation changes and characteristics in bipolar disorder

SARS-CoV-2 enzyme inhibitors among drugs screened for repurposing

Study reveals how high fat diets can cause intestinal and colon cancer

New cell-penetrating peptide may protect against life-threatening microbial inflammation

Researchers identify a common mechanism underlying diverse brain disorders

DNA on-off switches for SARS-CoV-2 host receptor as potential therapeutic targets

Smoking and vaping increase ACE2 levels and virus spike binding in airway epithelium

Researchers review the therapeutic potential of resveratrol nasal formulations in COVID-19

Researchers identify novel gene that controls sleep/wake cycle in mice

Researchers map potential toxicity of lanthanide metals used in medicine

Researchers uncover new gene mutation responsible for cerebral cavernous malformation

Researchers find new insight on the link between a gene and congenital heart disease

How SARS-CoV-2 variant B.1.1.7 adapted to evade innate immunity

Could the intranasal route be an alternate avenue of COVID-19 vaccination?

Researchers review environmental risk assessments for recombinant COVID-19 viral vector vaccines

New study could help guide oncologists in selecting the best treatment for kidney cancers

New chip mimicking bovine endometrium could play key role in cattle’s pregnancy success

Bacteria causing urinary tract infections can originate in meat-production chain

New generative model has wide implications in developmental biology, regenerative medicine

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Asthma Awareness: Fighting Asthma in 2021