Gene News and Research

Latest Gene News and Research

New therapeutic approach targets PCSK9 to regulate blood cholesterol levels

When the amount of cholesterol in the blood is too high, hypercholesterolemia can develop, causing serious damage to the arteries and cardiovascular health.

11 Jun 2025

Glucocorticoid receptor plays dual role in prostate cancer progression

A recent study from the Institute of Biomedicine at the University of Eastern Finland shows that the glucocorticoid receptor can both promote and inhibit prostate cancer progression, depending on the circumstances.

11 Jun 2025

Enhanced Genomics appoints Dietrich Stephan, Ph.D. as Chair of the Board to lead ambitious growth strategy

Enhanced Genomics (‘Enhanced’ or ‘the Company’), the biotechnology company pioneering 3D multi-omics to rapidly identify high-confidence, genetically validated drug targets for common diseases, today announced the appointment of Dietrich Stephan, Ph.D. as Chair of the Board of Directors.

11 Jun 2025

Maternal iron deficiency disrupts embryonic sex determination in mice

Developmentally expressed genes play a fundamental role in the formation of a wide range of organs. The Y chromosome-located mammalian sex-determining gene Sry, required for the formation of testis, is activated only within a narrow time window during embryogenesis.

11 Jun 2025

CHAF1B drives lung squamous cell carcinoma progression by repressing SETD7

CHAF1B, a histone chaperone component of the chromatin assembly factor-1 complex, is overexpressed in multiple cancers and linked to tumor progression, but its role in lung squamous-cell carcinoma (LUSC) remained unclear.

11 Jun 2025

Targeting metabolic reprogramming in breast cancer treatment

Breast cancer remains the most prevalent malignancy among women worldwide, posing a critical challenge to global health.

11 Jun 2025

Uncovering the genetic link between type 2 diabetes and brain structure

Type 2 diabetes mellitus (T2DM) is a highly prevalent metabolic disorder worldwide. Beyond glucose dysregulation, it exerts significant effects on the central nervous system.

11 Jun 2025

Protein ELAV identified as key regulator of circular RNAs in the brain

Deep within our nerve cells, a molecule is at work that has no beginning and no end. Instead of a straight chain, as is it common for most RNA strands, it forms a closed loop.

10 Jun 2025

When old diseases find new ways in: Europe’s latest diphtheria outbreak explained

A large multicountry outbreak of toxigenic Corynebacterium diphtheriae occurred among migrants entering Europe in 2022, driven primarily by cutaneous infections and involving multiple genetic lineages. Despite the unprecedented surge, transmission to resident populations was limited, but rising antimicrobial resistance and delayed treatment highlight ongoing public health risks.

10 Jun 2025

Study reveals a unique vulnerability in melanoma patients with neurofibromin 1 mutations

Increased activity in a specific biological pathway may explain why many patients with a deadly form of skin cancer do not respond to the latest cancer treatments, a new study shows.

10 Jun 2025

Methylation clocks may mislead anti-aging therapy evaluation

A new research perspective was published in Aging (Aging-US) Volume 17, Issue 5, on May 5, 2025, titled "Methylation clocks for evaluation of anti-aging interventions."

10 Jun 2025

Study of monozygotic twins reveals genetic factors linked with differences in environmental sensitivity

An international team of researchers led by King's College London have identified genetic factors that may make some individuals more or less sensitive to the environments they experience.

10 Jun 2025

Structural insights into IVD enzyme function and isovaleric acidemia

IVD is a key enzyme in leucine catabolism, catalyzing the conversion of isovaleryl-CoA to 3-methylcrotonyl-CoA.

10 Jun 2025

Patient-derived xenograft models may become an indispensable tool in precision oncology

Cancer remains one of the most pressing global health challenges, with millions of new diagnoses each year. While precision medicine and targeted therapies have transformed treatment strategies, many patients still face drug resistance and disease recurrence.

10 Jun 2025

Would you trust a life form engineered in a lab? Here’s why it matters

A new report from Rice University’s Baker Institute outlines six core ethical challenges in synthetic biology, including risks, equity, and environmental impacts.

9 Jun 2025

Study links reelin to cocaine-induced brain and behavior changes

Cocaine, a drug of abuse, activates just a portion - 10 to 20 percent - of the neurons in the brain's nucleus accumbens, a critical region linked to motivation and addiction.

9 Jun 2025

Study reveals the genetic underpinnings of a rare and aggressive ovarian cancer

A new study explains the genetic underpinnings of a rare and aggressive form of ovarian cancer – and offers a potential pathway for new treatments.

9 Jun 2025

New computational tool identifies the gene combinations underlying complex illnesses

Northwestern University biophysicists have developed a new computational tool for identifying the gene combinations underlying complex illnesses like diabetes, cancer and asthma.

9 Jun 2025

Spatial transcriptomics could transform musculoskeletal research

Conventional transcriptomic techniques have revealed much about gene expression at the population and single-cell level—but they overlook one crucial factor: spatial context.

9 Jun 2025

Study reveals mechanisms behind antibiotic-related immune disruptions in infants

In 2017, scientists at Cincinnati Children's revealed that using antibiotics to protect newborns from dangerous infections often comes with a long-term consequence-a permanently underdeveloped immune system that can make children prone to poor outcomes from future lung infections.

9 Jun 2025

Gene News and Research

Latest Gene News and Research

New therapeutic approach targets PCSK9 to regulate blood cholesterol levels

Glucocorticoid receptor plays dual role in prostate cancer progression

Enhanced Genomics appoints Dietrich Stephan, Ph.D. as Chair of the Board to lead ambitious growth strategy

Maternal iron deficiency disrupts embryonic sex determination in mice

CHAF1B drives lung squamous cell carcinoma progression by repressing SETD7

Targeting metabolic reprogramming in breast cancer treatment

Uncovering the genetic link between type 2 diabetes and brain structure

Protein ELAV identified as key regulator of circular RNAs in the brain

When old diseases find new ways in: Europe’s latest diphtheria outbreak explained

Study reveals a unique vulnerability in melanoma patients with neurofibromin 1 mutations

Methylation clocks may mislead anti-aging therapy evaluation

Study of monozygotic twins reveals genetic factors linked with differences in environmental sensitivity

Structural insights into IVD enzyme function and isovaleric acidemia

Patient-derived xenograft models may become an indispensable tool in precision oncology

Would you trust a life form engineered in a lab? Here’s why it matters

Study links reelin to cocaine-induced brain and behavior changes

Study reveals the genetic underpinnings of a rare and aggressive ovarian cancer

New computational tool identifies the gene combinations underlying complex illnesses

Spatial transcriptomics could transform musculoskeletal research

Study reveals mechanisms behind antibiotic-related immune disruptions in infants

eBook: Using iPSCs models for human disease research and drug discovery eBook

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?