Gene News and Research

Latest Gene News and Research

Celiac disease weakens gut microbes that digest fiber

Findings suggest that impaired fiber metabolism in celiac disease is due to microbial deficits, not just diet, emphasizing the need for targeted interventions.

2 Apr 2026

Do your genes dictate how your lifestyle choices impact aging?

Lifestyle-behavioral factors and socioeconomic status play an important role in shaping healthy aging, but their effects may differ depending on your DNA, according to a new international study led by Adelaide University researchers.

2 Apr 2026

New method improves reliability of protein language model predictions

AI language models, used to generate human-like text to power chatbots and create content, are also revolutionizing biology by treating complex biological data like a language.

1 Apr 2026

AEGIS tool helps scientists study evolution of aging and lifespan

Why do some species live for only weeks while others survive for centuries? Researchers at the Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) in Jena have developed AEGIS, a freely available software tool that enables scientists to simulate evolution on a standard computer and investigate how lifespan and aging evolve under different ecological pressures and genetic constraints.

1 Apr 2026

Gene-edited treatment shows promising outcomes for severe sickle cell disease

New results from a clinical trial show promising outcomes for a gene-edited treatment for severe sickle cell disease, a genetic blood disorder with few curative options.

1 Apr 2026

Targeted therapy pralsetinib improves outcomes in RET fusion-positive NSCLCs

In some non-small cell lung cancers (NSCLCs), changes to the RET gene (known as RET fusions) can drive tumor growth.

1 Apr 2026

Molecular switch in neurons found to limit the regrowth of damaged axonal fibers

Researchers from the Icahn School of Medicine at Mount Sinai have discovered a molecular switch in neurons that limits the regrowth of damaged axonal fibers.

1 Apr 2026

DNA damage in gray matter neurons linked to MS progression

For decades, multiple sclerosis research has focused on myelin, the insulation around the brain's wiring. Scientists paid less attention to another loss that was happening in parallel: neurons in the cortex, the seat of higher thinking and cognition, were quietly dying.

1 Apr 2026

Sleep duration and genetics interact to affect functional health

1 Apr 2026

Polygenic embryo testing raises ethical concerns beyond disease prevention

For more than four decades, in vitro fertilization (IVF) has helped families have children. Scientists estimate that more than 10 million people worldwide have been born through IVF and related assisted reproductive technologies, according to the International Committee for Monitoring Assisted Reproductive Technologies.

31 Mar 2026

How could bisphenol A raise depression risk? Study identifies six key molecular targets

An integrative Translational Psychiatry study linked BPA exposure to major depressive disorder by identifying 571 shared targets and six core genes, with genetic, transcriptomic, docking, and mouse-model data supporting plausible mechanistic pathways. The strongest signals pointed to AKT1, SRC, PLCG2, and JAK3 as potential contributors, while EGFR appeared protective.

31 Mar 2026

How vitamin D in the first 1,000 days may shape lifelong health

This narrative review argues that vitamin D is clearly important for skeletal health during the first 1,000 days of life and may also shape immune, metabolic, and selected neurodevelopmental pathways during early development. However, the authors stress that human evidence for most non-skeletal outcomes remains heterogeneous, with benefits appearing most consistent in populations with baseline deficiency.

31 Mar 2026

Innate immunity genes may influence earlier breast cancer onset in BRCA1 carriers

Damaging variants in genes involved in a rapid immune response (innate immunity) are significantly linked to earlier breast cancer onset in carriers of the harmful BRCA1 genetic mutation, reveal preliminary findings published online in the Journal of Medical Genetics.

31 Mar 2026

Lipid nanoparticles help CAR T cells melt pancreatic cancer barriers

Often diagnosed when surgery is no longer an option, pancreatic cancer is one of the most difficult cancers to treat and has one of the lowest rates of survival among major malignancies.

31 Mar 2026

Gene signature maps cholangiocarcinoma subtypes for precision treatment

Intrahepatic cholangiocarcinoma (iCCA), the second most common primary liver cancer after hepatocellular carcinoma, remains one of the most challenging malignancies to treat due to its highly concealed and heterogeneous nature.

31 Mar 2026

Antibiotic resistance genes found in both diseased and healthy lungs

The researchers examined patients with COPD, asthma, pulmonary fibrosis (IPF), and sarcoidosis, and compared them with healthy individuals.

31 Mar 2026

Excessive RNA editing enzyme alters brain circuit formation in Down syndrome

A collaborative research study co-led by scientists at the Icahn School of Medicine at Mount Sinai and the Liber Institute for Brain Development has for the first time identified a biological process that may help explain how the brain develops differently in people with Down syndrome.

31 Mar 2026

Broken String Biosciences rebrands to reflect strategic evolution as demand grows for unbiased genome-wide off-target analysis

Broken String Biosciences, a biotechnology company enabling gene editing teams to accelerate development of safer, more effective genetic medicines, today introduced new branding and comprehensive website as part of its strategic repositioning.

From Broken String Biosciences 31 Mar 2026

Why vaginal microbiota transplants aren’t working yet

Vaginal microbiota transplantation without antibiotics fails to restore microbiome balance, yet engraftment suggests avenues for enhancing treatment efficacy.

31 Mar 2026

New genetic ‘roadmap’ advances precision therapy for intrahepatic cholangiocarcinoma

The 1,341-gene signature for intrahepatic cholangiocarcinoma offers a framework for precise diagnosis and tailored therapies, addressing tumor heterogeneity.

From BGI Genomics 31 Mar 2026