Gene News and Research

Latest Gene News and Research

Machine learning models can help diagnose ALS earlier from a blood sample

Using machine learning models, researchers at Michigan Medicine have identified a potential way to diagnose amyotrophic lateral sclerosis, or ALS, earlier from a blood sample, a study suggests.

10 Dec 2025

Study shines new light on how cancer avoids the mitotic stopwatch pathway

When cell division (mitosis) takes too long, it can be a sign that something is wrong with the cells, for example DNA damage or chromosomal instability.

10 Dec 2025

$EpilepsyGTx raises $33 million Series A to develop single dose gene therapy for focal refractory epilepsy$

EpilepsyGTx raises $33 million Series A to develop single dose gene therapy for focal refractory epilepsy

EpilepsyGTx, a biotechnology company focused on research and development of cutting-edge gene therapies to treat refractory epilepsy, today announced it has raised $33 million in a Series A financing to advance its lead program EPY201 through Phase 1/2a clinical trials.

10 Dec 2025

VALANX Biotech establishes Board of Directors

VALANX Biotech (VALANX), a biotech company developing novel antibody-drug-conjugate (ADC) assets enabled by its GoldenSite™ site-specific protein conjugation technology, today announced the formation of its Board of Directors.

10 Dec 2025

Sterilized fermented beverage targets obesity and type 2 diabetes pathways in computational study

Researchers profiled a terminally sterilized probiotic-fermented MFH beverage and identified aporphine alkaloids and flavonoids with favorable predicted ADMET properties. Integrated network pharmacology, molecular docking, and 100-ns MD simulations suggest multi-target engagement of metabolic-inflammatory pathways relevant to obesity and type 2 diabetes.

9 Dec 2025

Researchers discover new biomarker of "complicated" mild- to severe-pediatric traumatic brain injury

Researchers at the University of Pittsburgh and UPMC Children's Hospital of Pittsburgh discovered a promising new biomarker of "complicated" mild- to severe-pediatric traumatic brain injury, or TBI.

9 Dec 2025

Nanoflower-treated stem cells deliver healthier mitochondria to stressed cells

This study shows that vacancy-engineered MoS₂ nanoflowers drive mitochondrial biogenesis in human mesenchymal stem cells by activating SIRT1–PGC-1α signaling and reducing oxidative stress. These treated cells transfer more functional mitochondria to injured recipient cells, restoring energy metabolism and redox balance in multiple in vitro models.

9 Dec 2025

AI-driven method uncovers genetic interactions that fuel cancer progression

University of South Australia scientists have developed a powerful new way to uncover the genetic interactions that fuel cancer progression, paving the way for earlier and more precise treatments.

9 Dec 2025

Small molecule discovery could open the door to new class of treatments for hard-to-treat cancers

Researchers at the UCLA Health Jonsson Comprehensive Cancer Center have identified a small molecule that can inhibit a cancer-driving protein long considered impossible to target with drugs - a discovery that could open the door to a new class of treatments for leukemia and other hard-to-treat cancers.

9 Dec 2025

Brain function discovery helps explain why childhood adversity raises metabolic disease risk in women

McGill University researchers have identified a brain function that helps explain why childhood stress raises metabolic health risks for some women later in life.

9 Dec 2025

Australian researchers pinpoint specific genetic changes linked to severe AMD

Australian researchers have for the first time pinpointed specific genetic changes that increase the risk of severe, sight-threatening forms of age-related macular degeneration (AMD).

9 Dec 2025

Everyday PFAS exposure alters placental function in early pregnancy

This study measured real-life PFAS concentrations in first-trimester human placentas and used these data to create a pregnancy-relevant PFAS mixture. In 3D trophoblast spheroid models, the mixture altered invasion, hormone secretion, and gene expression without broadly reducing viability at environmentally relevant doses.

8 Dec 2025

Genome-edited immune cell therapy shows promise for treating aggressive blood cancer

A groundbreaking new treatment using genome-edited immune cells, developed by scientists at UCL (University College London) and Great Ormond Street Hospital (GOSH), has shown promising results in helping children and adults fight a rare and aggressive form of blood cancer called T-cell acute lymphoblastic leukemia (T-ALL).

8 Dec 2025

Study reveals new genetic insights into reticular pseudodrusen in people with AMD

A study funded in part by the National Institutes of Health (NIH) has revealed important insights into the genetics of deposits in the eye, known as reticular pseudodrusen (RPD), that are linked to greater risk of vision loss among people with age-related macular degeneration (AMD).

8 Dec 2025

Industrial and farm chemicals quietly alter the balance of gut microbes

This study systematically screened over 1,000 agricultural and industrial chemicals and found that many can inhibit human gut bacteria in vitro. Beyond antimicrobial effects, these chemicals act as selective pressures that can reshape microbial competition, tolerance mechanisms, and metabolic pathways.

8 Dec 2025

Timing of genetic mutation dictates childhood leukemia aggressiveness

A team of researchers at the Icahn School of Medicine at Mount Sinai has uncovered why children with the same leukemia-causing gene mutation can have dramatically different outcomes: it depends on when in development the mutation first occurs.

8 Dec 2025

Serious side effects after CAR T cell therapy for multiple myeloma share a common immune root cause

Serious side effects, including neurotoxicity and intestinal inflammation, that appear weeks or months after patients receive CAR T cell therapy for multiple myeloma share a common immune root cause, are associated with high rates of death unrelated to cancer relapse-primarily infection-and may be avoidable.

8 Dec 2025

JAX wins $30 million contract to create computational "digital twins" of the human heart

Developing new drugs is one of the riskiest and most expensive endeavors in science. Today, The Jackson Laboratory (JAX) announced a bold initiative to improve that trajectory, powered by an up to $30 million contract from the Advanced Research Projects Agency for Health (ARPA-H) Computational ADME-Tox and Physiology Analysis for Safer Therapeutics (CATALYST) program.

8 Dec 2025

A slow-growing, bone-covered, noncancerous mass named as ossifying spindled and epithelioid tumor

It's not often that a pathologist gets to make a diagnosis that works for the patient by preventing treatment from occurring.

8 Dec 2025

New combination treatment offers significant benefits for people with recurring grade 3 astrocytoma

Huntsman Cancer Institute at the University of Utah (the U) participated in a clinical trial that found that a new combination treatment plan helped people with recurring grade 3 astrocytoma, an aggressive form of brain cancer, live longer.

8 Dec 2025

Gene News and Research

Latest Gene News and Research

Machine learning models can help diagnose ALS earlier from a blood sample

Study shines new light on how cancer avoids the mitotic stopwatch pathway

EpilepsyGTx raises $33 million Series A to develop single dose gene therapy for focal refractory epilepsy

VALANX Biotech establishes Board of Directors

Sterilized fermented beverage targets obesity and type 2 diabetes pathways in computational study

Researchers discover new biomarker of "complicated" mild- to severe-pediatric traumatic brain injury

Nanoflower-treated stem cells deliver healthier mitochondria to stressed cells

AI-driven method uncovers genetic interactions that fuel cancer progression

Small molecule discovery could open the door to new class of treatments for hard-to-treat cancers

Brain function discovery helps explain why childhood adversity raises metabolic disease risk in women

Australian researchers pinpoint specific genetic changes linked to severe AMD

Everyday PFAS exposure alters placental function in early pregnancy

Genome-edited immune cell therapy shows promise for treating aggressive blood cancer

Study reveals new genetic insights into reticular pseudodrusen in people with AMD

Industrial and farm chemicals quietly alter the balance of gut microbes

Timing of genetic mutation dictates childhood leukemia aggressiveness

Serious side effects after CAR T cell therapy for multiple myeloma share a common immune root cause

JAX wins $30 million contract to create computational "digital twins" of the human heart

A slow-growing, bone-covered, noncancerous mass named as ossifying spindled and epithelioid tumor

New combination treatment offers significant benefits for people with recurring grade 3 astrocytoma

Genomics - Industry Focus eBook (2nd edition) eBook

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre