Gene News and Research

Latest Gene News and Research

Combined CDK4/6 and EGFR inhibition improves pancreatic cancer therapy

Clinically available KRAS inhibitors mainly target G12C, which is rare in PDAC and often acquires resistance. Oncogenic KRAS inactivates RB1 via CDK4/6, while RB1 mutation is rare.

13 Mar 2026

Pen-strep treatment rewires mechanical sensing in immune cells

Macrophages are central to mechanobiology research: their physical characteristics-stiffness, adhesion, and ECM (extracellular matrix) sensing-are inextricably linked to their phenotypic polarization and immune function.

13 Mar 2026

Scientists win awards for the discovery of genomic imprinting and tumor’s power grid

For their discovery of genomic imprinting, developmental biologists Davor Solter and Azim Surani will receive the 2026 Paul Ehrlich and Ludwig Darmstaedter Prize, endowed with €120,000, on March 14 at Frankfurt’s Paulskirche.

13 Mar 2026

Review examines clinical trial phases in drug development

Announcing a new article publication for BIO Integration journal. Clinical trials bridge basic research and clinical application, serving as essential steps in drug development.

13 Mar 2026

Predicting cancer behavior through splicing fingerprints

Cancer is caused by faulty genes, but what also shapes a cancer cell's behaviour is how a gene's instructions are trimmed and rearranged before they are turned into the proteins that keep a cell alive.

13 Mar 2026

Lifelong tracking of fish reveals early behavioral signals of aging

Scientists tracking the entire life of the African turquoise killifish have discovered that behavior alone can predict whether an animal will live a long or short life.

12 Mar 2026

New imaging method maps gene activity across entire zebrafish embryo

How does a tiny cluster of cells become an embryo with a head, trunk, and tail? And how do thousands of genes coordinate this development?

12 Mar 2026

Experimental therapy eliminates pancreatic precancerous cells in mice study

A new preclinical study in mice shows that precancerous cells in the pancreas can be eliminated before they have the chance to become tumors.

12 Mar 2026

Scientists uncover unexpected cancer target on tumor cell surfaces

For five decades, scientists have known about a notorious cancer-causing enzyme called SRC. But they always assumed it only appeared on the inside of cells, where it sent signals that fueled tumor growth and stayed hidden from the immune system.

12 Mar 2026

Study identifies immune cells and RANK protein as fertility regulators

The kick off signal for puberty begins in the brain. Specifically, in the hypothalamus, where specific neurons release a hormone that activates the hypophysis, at the base of the skull, which then releases other hormones to start gonad –ovaries or testicles –maturation.

12 Mar 2026

Adding three simple amino acids boosts mRNA and CRISPR delivery

Lipid nanoparticles, or LNPs, best known as the delivery vehicle for the COVID-19 mRNA vaccines received by billions of people, are now at the center of a much larger medical revolution.

12 Mar 2026

Immune switch plays a critical role in successful pregnancies

Early pregnancy depends on a remarkable act of coordination. Before the placenta can nourish a growing fetus, the embryo must securely "land" and connect with the mother's blood supply - a process guided by a specialized group of immune cells called uterine natural killer cells, or uNK cells.

12 Mar 2026

The 0.05 EU/mg breakthrough: How Sino Biological ProPure™ is redefining the Ultra-Low Endotoxin standard

When we discuss bacterial infections, we often think of exotoxins—those soluble proteins actively secreted by bacteria—while overlooking endotoxins, which are more insidious but equally dangerous.

From Sino Biological Inc. 12 Mar 2026

Hanson Wade - 7th Gene Therapy Analytical Development Summit Europe

Clinical and Regulatory Momentum Puts Gene Therapy Analytics in the Spotlight Ahead of the 7th Gene Therapy Analytical Development Summit.

From Hanson Wade Group - 7th Gene Therapy Analytical Development Europe 12 Mar 2026

Japan's famous matcha could reduce sneezing in people with nasal allergies

There's now another reason to love Japan's famous matcha: a study in mice suggests that the green tea powder could reduce the need to sneeze in people with nasal allergies.

11 Mar 2026

Dual-positive hybrid cells linked to shorter survival in advanced breast cancer

An enigmatic type of circulating tumor cell called a dual-positive (DP) cell is associated with shorter survival time in patients with advanced breast cancer, according to a study led by investigators at Weill Cornell Medicine and NewYork-Presbyterian.

11 Mar 2026

Detailed APOL1 gene analysis in Black patients improves kidney disease diagnosis

A closer examination of the APOL1 gene in Black patients with kidney disease can provide more accurate diagnoses than current protocols, a new study from researchers at Columbia University Vagelos College of Physicians and Surgeons has found.

11 Mar 2026

Scientists map epigenetic changes across aging brain cells

Neurodegenerative diseases affect more than 57 million people globally. The incidence of these diseases, from Alzheimer's to Parkinson's to ALS and beyond, is expected to double every 20 years.

11 Mar 2026

DNA-based barcoding reveals which nanoparticles successfully deliver genetic therapies

Drug delivery researchers have vastly improved the potential of genetic therapies by overcoming the challenge of consistently getting genes and gene-editing tools where they need to be within cells.

11 Mar 2026

Low testosterone and high fructose intake can worsen fatty liver disease

Low testosterone in itself can cause a variety of health problems, but the addition of a poor diet can exacerbate certain conditions. Metabolic dysfunction-associated steatotic liver disease (MASLD) is one example that approximately 40% of adult men worldwide currently suffer from and has become a global problem.

11 Mar 2026