Gene News and Research

Latest Gene News and Research

UBQLN2 liquid droplets emerge as key catalysts of early α-synuclein aggregation

Parkinson's disease (PD) is an age-related, progressive neurodegenerative disorder. The hallmark of PD pathogenesis is the Lewy bodies (LBs) that accumulate in neurons in the substantia nigra region of the brain, damaging these neurons and leading to the motor symptoms of the disease.

26 Nov 2025

Shared genetic roots between delirium and Alzheimer’s disease

This study reveals genetic and proteomic risk factors for delirium, offering insights into its etiology and potential biomarkers for prediction and prevention.

26 Nov 2025

Researchers discover new mutation hotspot in the human genome

Researchers have discovered new regions of the human genome particularly vulnerable to mutations. These altered stretches of DNA can be passed down to future generations and are important for how we study genetics and disease.

26 Nov 2025

Study overturns assumptions about PTPN22 risk gene’s role in interferon production

A new paper from the University of Kansas overturns the idea that a "risk gene" carried by millions of people worldwide influences production of Type 1 interferon, a workhorse of the immune system.

25 Nov 2025

Genetic signals reveal why erectile dysfunction develops and who is most at risk

This multi-ancestry genomic study identifies key genetic loci underlying erectile dysfunction and shows that ED risk is shaped by both cardiometabolic and substance use–related genetic pathways. Using EHR-linked data, the researchers uncover SIM1-related mechanisms, modest PRS performance, and bidirectional genetic links with obesity, diabetes, and addiction traits.

25 Nov 2025

New medication offers potential treatment for patients with deadliest form of blood cancer

Biomedical research that began at the University of Virginia School of Medicine has yielded a much-needed new treatment for patients with the deadliest form of blood cancer.

25 Nov 2025

Study elucidates how anti-amyloid antibody therapy lecanemab works in Alzheimer's disease

Lecanemab, sold under the name Leqembi, is a monoclonal antibody therapy for Alzheimer's disease that clears toxic amyloid plaques and delays cognitive decline.

25 Nov 2025

Computational modeling helps simulate key stages of retinogenesis

New computer modeling could help scientists better understand how the retina regenerates, opening the door to new treatments for vision loss, according to a study from the University of Surrey.

25 Nov 2025

Scientists uncover how brain enzyme OTULIN controls tau expression

Scientists have uncovered a surprising mechanism by which a brain enzyme called OTULIN controls the expression of tau, the protein that forms toxic tangles in Alzheimer's disease.

25 Nov 2025

Discovery reveals role of EGFR in resistance to KRAS inhibitors in pancreatic cancer

A study led by University of Cincinnati Cancer Center researchers sheds new light on how pancreatic cancer cells resist treatment and points to potential new combination therapies to make treatments more effective.

24 Nov 2025

Scientists reverse aging in blood stem cells by restoring lysosome function

Researchers at the Icahn School of Medicine at Mount Sinai have discovered how to reverse aging in blood-forming stem cells in mice by correcting defects in the stem cell's lysosomes.

24 Nov 2025

Single-cell RNA sequencing uncovers diverse CD4⁺ T-cell subtypes in pediatric lupus

Detailed mapping of CD4⁺ T cells from children with systemic lupus erythematosus (SLE) has revealed distinct immune cell subsets with likely roles in disease pathogenesis, according to a study led by Weill Cornell Medicine investigators.

24 Nov 2025

New insights into ribosome collisions and stress response

LMU researchers uncover the mechanism by which ribosomes raise alarms in the cell.

24 Nov 2025

Identifying vulnerabilities and new targets for hard-to-treat carcinomas

Some tumors are almost impossible to treat. That's especially true for carcinomas, which don't behave like other malignancies.

24 Nov 2025

New discovery could reshape how scientists think about Alzheimer’s treatment

Rutgers neuroscientist Peng Jiang was visiting his hometown of Qianshan, a city in China's Anhui province, when a neighbor came to his parents' house with a story that would stay with him.

24 Nov 2025

Researchers use organoids to study the earliest moments of electrical activity in the brain

Humans have long wondered when and how we begin to form thoughts. Are we born with a pre-configured brain, or do thought patterns only begin to emerge in response to our sensory experiences of the world around us? Now, science is getting closer to answering the questions philosophers have pondered for centuries.

24 Nov 2025

Kimchi consumption strengthens antigen recognition and immune regulation

Amid concerns about the simultaneous spread of multiple respiratory diseases, such as colds and influenza, with the change of seasons in current times, a recent clinical study has scientifically proven that kimchi, a traditional Korean fermented food, enhances the function of human immune cells and maintains the balance of the immune system.

24 Nov 2025

Hearing loss emerges as a key early warning sign for Alzheimer disease

Hearing loss also predicts a significantly higher risk of dementia, especially in APOE ε4 carriers, highlighting its value as an early risk marker.

23 Nov 2025

Study finds GLP-1 drugs improve strength and reverse aging biology in mice

Researchers showed that GLP-1 receptor agonism counteracts aging across multiple organs in mice, improving strength and reversing molecular aging signatures without meaningful effects on body weight. These benefits depended largely on hypothalamic GLP-1R signaling and closely mirrored the anti-aging patterns produced by rapamycin.

23 Nov 2025

Discovery of sequence-driven DNA methylation offers new path for epigenetic engineering

All the cells in an organism have the exact same genetic sequence. What differs across cell types is their epigenetics-meticulously placed chemical tags that influence which genes are expressed in each cell.

22 Nov 2025

Gene News and Research

Latest Gene News and Research

UBQLN2 liquid droplets emerge as key catalysts of early α-synuclein aggregation

Shared genetic roots between delirium and Alzheimer’s disease

Researchers discover new mutation hotspot in the human genome

Study overturns assumptions about PTPN22 risk gene’s role in interferon production

Genetic signals reveal why erectile dysfunction develops and who is most at risk

New medication offers potential treatment for patients with deadliest form of blood cancer

Study elucidates how anti-amyloid antibody therapy lecanemab works in Alzheimer's disease

Computational modeling helps simulate key stages of retinogenesis

Scientists uncover how brain enzyme OTULIN controls tau expression

Discovery reveals role of EGFR in resistance to KRAS inhibitors in pancreatic cancer

Scientists reverse aging in blood stem cells by restoring lysosome function

Single-cell RNA sequencing uncovers diverse CD4⁺ T-cell subtypes in pediatric lupus

New insights into ribosome collisions and stress response

Identifying vulnerabilities and new targets for hard-to-treat carcinomas

New discovery could reshape how scientists think about Alzheimer’s treatment

Researchers use organoids to study the earliest moments of electrical activity in the brain

Kimchi consumption strengthens antigen recognition and immune regulation

Hearing loss emerges as a key early warning sign for Alzheimer disease

Study finds GLP-1 drugs improve strength and reverse aging biology in mice

Discovery of sequence-driven DNA methylation offers new path for epigenetic engineering

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