Gene News and Research

Latest Gene News and Research

Researchers identify genetic toolkit to reprogram cells into immune sentinels

An international team led by researchers at Lund University in Sweden has identified the molecular tools needed to reprogram ordinary cells into specialized immune cells.

29 Aug 2025

Daily use of low-dose colchicine may slow growth of blood mutations linked to disease

Taking low-dose colchicine daily may slow the progression of a common acquired gene mutation found in the blood of older adults that can lead to certain blood cancers and increased risk of cardiovascular disease, according to a subanalysis of the LoDoCo2 trial published in JACC, the flagship journal of the American College of Cardiology, and simultaneously presented at ESC Congress 2025.

29 Aug 2025

Clonogenic hepatocytes identified as engines of liver development

In a new study published in the Journal of Hepatology, researchers from the San Raffaele Telethon Institute for Gene Therapy (SR-Tiget) show that only 15–20% of hepatocytes in newborn mice - dubbed clonogenic hepatocytes - are responsible for generating over 90% of the adult liver mass.

29 Aug 2025

Signaling mechanisms driving olfactory neurogenesis in zebrafish

Cellular differentiation of stem cells into specialized cells requires many steps, including division, to create more cells; fate determination, which is a commitment to a specific lineage or developmental path; and migration, to integrate the cell into its final location.

29 Aug 2025

Research sheds new light on depression’s biological roots

Researchers at McGill University and the Douglas Institute have identified two specific types of brain cells that are altered in people with depression.

28 Aug 2025

Study brings hope for a more personalized approach to treat ER+ breast cancer

A new study from researchers at Baylor College of Medicine brings hope for a more personalized approach to treat estrogen receptor-positive (ER+) breast cancer, the most common type of this cancer.

28 Aug 2025

Molecular profiling identifies prostate cancer patients who benefit most from chemotherapy

Testing the molecular profile of tumors identifies which patients with advanced prostate cancer are more likely to benefit from chemotherapy and live longer, sparing patients less likely to benefit from unpleasant side effects, according to a new study led by UCL researchers.

28 Aug 2025

Probiotic enhances cholesterol drug efficacy but raises safety concerns at high doses

A recent study published in Engineering has shed light on the complex interactions between probiotics and drugs, particularly focusing on the effects of the probiotic Lacticaseibacillus paracasei Zhang (LCZ) on the cholesterol-lowering drug lovastatin.

28 Aug 2025

Single gene discovery reveals key sex difference in immune response

A new study has uncovered a key difference between the immune system of males and females - and it comes down to a single gene.

28 Aug 2025

Killifish study reveals multi-generational impacts of exposure to crude oil and flame retardants

A tiny fish with transparent embryos is helping University of California, Davis, researchers shed light on how exposure to crude oil and flame retardants can affect behavior, skeletal growth, cardiac health and other internal functions in offspring and subsequent generations.

28 Aug 2025

Hormone therapy type may influence postmenopausal cognitive health

The type of estradiol-based hormone therapy taken during and after menopause, such as patches or pills, may be associated with differences in memory performance, according to a study published on August 27, 2025, in Neurology, the medical journal of the American Academy of Neurology.

28 Aug 2025

Regenerative strategy offers hope for women with pelvic organ prolapse

Pelvic organ prolapse (POP) is a disorder that primarily affects older women who have experienced multiple vaginal childbirths.

27 Aug 2025

Abnormal fusion protein drives childhood brain tumor through condensate formation

A study looking at the biophysical properties of an abnormal protein driving cancer cells is giving scientists new therapeutic clues for how to treat ependymoma, the third most common childhood brain tumor.

27 Aug 2025

Gene editing therapy exa-cel improves quality of life in sickle cell disease and beta thalassemia

Treatment with exagamglogene autotemcel (exa-cel) led to robust and sustained improvements in quality of life for patients with severe sickle cell disease (SCD) or transfusion-dependent beta thalassemia, according to two studies published in Blood Advances.

27 Aug 2025

Gene News and Research

Latest Gene News and Research

Researchers identify genetic toolkit to reprogram cells into immune sentinels

Daily use of low-dose colchicine may slow growth of blood mutations linked to disease

Clonogenic hepatocytes identified as engines of liver development

Signaling mechanisms driving olfactory neurogenesis in zebrafish

Research sheds new light on depression’s biological roots

Study brings hope for a more personalized approach to treat ER+ breast cancer

Molecular profiling identifies prostate cancer patients who benefit most from chemotherapy

Probiotic enhances cholesterol drug efficacy but raises safety concerns at high doses

Single gene discovery reveals key sex difference in immune response

Killifish study reveals multi-generational impacts of exposure to crude oil and flame retardants

Hormone therapy type may influence postmenopausal cognitive health

Regenerative strategy offers hope for women with pelvic organ prolapse

Abnormal fusion protein drives childhood brain tumor through condensate formation

Gene editing therapy exa-cel improves quality of life in sickle cell disease and beta thalassemia

CURE GABA-A and Grann Pharmaceuticals announce global partnership to advance rare neurological therapies

Shared gene signatures reveal metabolic dysfunction in liver cirrhosis and acute-on-chronic liver failure

Genetic variants mimicking IL-6 inhibition linked to lower cardiovascular risk

Mitochondria fight infection by starving parasites of essential nutrients

Investigating toxicity of common bisphenol replacements in food packaging

Probiotics limit the spread of drug-resistant genes in preemies

eBook: Using iPSCs models for human disease research and drug discovery eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging