Gene News and Research

Latest Gene News and Research

Researchers identify early functional deficiencies in neurons derived from Parkinson's patients

Researchers from IDIBELL and the University of Barcelona have described that neurons derived from Parkinson's patients show impairments in their transmission before neurodegeneration.

7 Jul 2021

Study addresses potential interrelations between AID/APOBECs and the SARS-CoV-2 virus

Together with their multifaceted action mechanisms, activation-induced cytidine deaminase (AID) and so-called APOBEC proteins are important factors in the body's immune response and offer fast and effective protection against a large number of DNA and RNA viruses.

7 Jul 2021

Study identifies specialized immune cells that sculpt inhibitory neurons to regulate brain wiring

From the bark of a puppy to the patter of rain against the window, our brains receive countless signals every second. Most of the time, we tune out inconsequential cues--the buzz of a fly, the soft rustle of leaves in the tree--and pay attention to important ones--the sound of a car horn, a bang on the door.

7 Jul 2021

Research shows how loss of de-N-glycosylation enzyme causes detrimental effects

Peptide: N-glycanase (NGLY1) is an evolutionarily conserved enzyme for removing N-linked glycans (N-glycans) from glycoproteins and is involved in proteostasis of N-glycoproteins in the cytosol. In 2012, a rare genetic disorder called NGLY1 deficiency was discovered by an exome analysis.

7 Jul 2021

Uncovering cellular mechanism related to gene silencing therapies

Gene silencing therapies are used to interfere with, or "silence", the expression of genes that are associated with disorders. Now, a team at TMDU has uncovered some of the cellular mechanisms by which the silencing therapies act in cells.

7 Jul 2021

Skin pigmentation mechanism confers major protection against UV-related cancers

A skin pigmentation mechanism that can darken the color of human skin as a natural defense against ultraviolet (UV)-associated cancers has been discovered by scientists at Massachusetts General Hospital (MGH).

7 Jul 2021

SARS-CoV-2 Lambda variant spreading rapidly in South America, report reveals

A new research paper by researchers in Peru describes a new variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) known as the Lambda variant (C.37). The Lambda variant was first reported in Lima, Peru, in December 2020, and from April 2021, nearly all the coronavirus infections in the country are caused by it.

7 Jul 2021

New discovery provides clues to elucidate the pathogenesis of muscle diseases

A research collaboration based in Kumamoto University, Japan has discovered that muscles and the resident stem cells (satellite cells) responsible for muscle regeneration retain memory of their location in the body.

6 Jul 2021

NYUAD researchers unlock an epigenetic code that allows liver regeneration

NYU Abu Dhabi researchers uncovered a code that sets the genome of the liver to account for the remarkable ability for this organ to regenerate.

6 Jul 2021

Comprehensive genetic study provides new insights on cleft lip and palate

Cleft lip and palate is one of the most common congenital malformations. Its causes are mainly genetic. However, it is still largely unknown exactly which genes are affected.

6 Jul 2021

Researchers unravel mechanisms that produce individualized metabolism in leukemia

A research collaboration based in Kumamoto University (Japan) has shown that lysine-specific demethylase 1 (LSD1), an enzyme involved in gene expression, produces individualized metabolism depending on the type of acute myeloid leukemia cells.

6 Jul 2021

Deletion of an embryonic gene in liver cells completely wipes out bile ducts of newborn mice

Scientists from the University of Pittsburgh School of Medicine described a new phenomenon in which the deletion of a single gene involved in liver embryogenesis completely wipes out bile ducts of newborn mice.

6 Jul 2021

Brain cells snap DNA strands in numerous locations to make memories

The urgency to remember a dangerous experience requires the brain to make a series of potentially dangerous moves: Neurons and other brain cells snap open their DNA in numerous locations--more than previously realized, according to a new study--to provide quick access to genetic instructions for the mechanisms of memory storage.

6 Jul 2021

Gene-edited cellular therapeutics can successfully treat cardiovascular and pulmonary diseases

Scientists at UC San Francisco have shown that gene-edited cellular therapeutics can be used to successfully treat cardiovascular and pulmonary diseases, potentially paving the way for developing less expensive cellular therapies to treat diseases for which there are currently few viable options.

6 Jul 2021

New method expands view into activity of single cells

Researchers have devised a way to multiply by more than ten-fold the accessible details of gene activity in individual cells. It's a big leap in the effort to understand cancer development, brain function, immunity and other biological processes driven by the complex interactions of multitudes of different cell types.

6 Jul 2021

Study explores the effects of SARS-CoV-2 (and other betacoronaviruses) on cellular mRNA processing

A new study has been released on the bioRxiv* preprint server, which deals with a comprehensive survey on alternative splicing concerning SARS-CoV-2 infection. This study has also included two other betacoronavirurses (SARS-CoV and MERS), a control set of unrelated viruses, and a bacterium, namely, Streptococcus pneumonia. The study findings suggest that several cellular parameters are affected owing to a betacoronavirus infection, which in turn affects some genes and invariably various biological functions.

6 Jul 2021

Developing a face mask that can detect COVID-19

A face mask has been developed that can detect COVID-19. News-Medical spoke to the researchers behind this idea to find out more about how it works.

6 Jul 2021

COVID-19 recovered vaccinated individuals more protected from Delta variant

The B.1.617 lineage of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first detected in October 2020, has led to new outbreaks of the infection and new waves of the pandemic. This infectious lineage has resulted in the generation of sub-lineages such as B.1.617.1 (Kappa), B.1.617.2 (Delta) and B.1.617.3.

6 Jul 2021

Researchers seek to find a cure for the deadliest solid tumor in children

Australian researchers and oncologists have been awarded $2.4 million to investigate the causes and treatments for neuroblastoma, the deadliest and most common solid tumor in children under the age of five.

5 Jul 2021

Research reveals the role of dopamine in how songbirds learn complex new sounds

Neuroscientists at the University of Massachusetts Amherst have demonstrated in new research that dopamine plays a key role in how songbirds learn complex new sounds.

5 Jul 2021

Gene News and Research

Latest Gene News and Research

Researchers identify early functional deficiencies in neurons derived from Parkinson's patients

Study addresses potential interrelations between AID/APOBECs and the SARS-CoV-2 virus

Study identifies specialized immune cells that sculpt inhibitory neurons to regulate brain wiring

Research shows how loss of de-N-glycosylation enzyme causes detrimental effects

Uncovering cellular mechanism related to gene silencing therapies

Skin pigmentation mechanism confers major protection against UV-related cancers

SARS-CoV-2 Lambda variant spreading rapidly in South America, report reveals

New discovery provides clues to elucidate the pathogenesis of muscle diseases

NYUAD researchers unlock an epigenetic code that allows liver regeneration

Comprehensive genetic study provides new insights on cleft lip and palate

Researchers unravel mechanisms that produce individualized metabolism in leukemia

Deletion of an embryonic gene in liver cells completely wipes out bile ducts of newborn mice

Brain cells snap DNA strands in numerous locations to make memories

Gene-edited cellular therapeutics can successfully treat cardiovascular and pulmonary diseases

New method expands view into activity of single cells

Study explores the effects of SARS-CoV-2 (and other betacoronaviruses) on cellular mRNA processing

Developing a face mask that can detect COVID-19

COVID-19 recovered vaccinated individuals more protected from Delta variant

Researchers seek to find a cure for the deadliest solid tumor in children

Research reveals the role of dopamine in how songbirds learn complex new sounds

World Brain Day 2021: An interview with Professor Alan Thompson

Preventing lethal blood clots

Curbing COVID-19 through border controls and restricted entry