Gene News and Research

Latest Gene News and Research

New insights reveal EGFR as a target in KRAS-mutated colon cancer

KRAS mutations are among the most common genetic alterations in cancer and are considered particularly difficult to treat.

26 May 2025

NUS researchers develop breakthrough gene delivery technology for immune cells

Researchers at the National University of Singapore (NUS) have developed a scalable, non-viral technology that efficiently delivers genetic material into human immune cells.

26 May 2025

Experts explain how H5 avian influenza adapts to infect more animals

The Gs/Gd lineage of highly pathogenic H5 avian influenza viruses—including H5N1—has rapidly evolved, spreading globally and infecting a growing range of birds, mammals, and occasionally humans. This review highlights the expanding risks, the challenges of cross-species transmission, and urgent needs for surveillance, vaccination, and a unified One Health response.

25 May 2025

New blood test speeds up diagnosis of rare childhood diseases

A new, rapid testing method will greatly help the diagnosis of rare diseases in babies and children, according to research to be presented to the annual conference of the European Society of Human Genetics today (Monday).

25 May 2025

Genetic discovery sheds light on infection-triggered neuropathy

Neuropathy, a disorder in which damage to nerves can impair sensation and movement, has many causes, including infection.

25 May 2025

Rare cancer gene found in sperm donor sparks European regulatory concerns

A case in which a sperm donor was later found to be carrying a cancer-causing pathogenic variant in his gametes has highlighted the problems of regulating gamete donation at European and international level, the annual conference of the European Society of Human Genetics will hear today (Saturday).

23 May 2025

Fungal antiviral responses controlled by RNA editing and transcription factor dynamics

The expression of symptoms of viral infections is a byproduct of complex virus-host molecular pathways.

23 May 2025

New cryogenic mass spectrometry approach reveals inner structure of lipid nanoparticles

Scientists have developed a method for analysing the structure of lipid nanoparticles that could be used to improve vaccine and drug delivery, targeting a wide range of health issues.

23 May 2025

Tuberculosis bacteria use molecular switch to pause and restart growth

The bacteria that cause tuberculosis (TB) may have an "on-off switch" that lets them pause and restart growth, according to a new study from the University of Surrey and the University of Oxford.

23 May 2025

Aging metabolism reduces effectiveness of CAR-T cell therapy

A Ludwig Cancer Research study has discovered that the metabolic decline that accompanies aging impairs the efficacy of CAR-T cell therapy, an immunotherapy in which T cells of the immune system are taken from patients, engineered to target cancer cells and reinfused into the same patients for treatment.

23 May 2025

Experimental ALS drug shows unprecedented recovery in some patients

When Columbia neurologist and scientist Neil Shneider speaks to his ALS patients who volunteer for experimental therapies, he's unwaveringly honest.

23 May 2025

Waters acquires Halo Labs, expanding biological analysis portfolio

Waters Corporation today announced that it has acquired Halo Labs™, an innovator of specialized imaging technologies to detect, identify, and count interfering materials (particles) in therapeutic products, such as cell, protein, and gene therapies.

From Waters Corporation 23 May 2025

Powerful new toolkit targets vision loss in advanced retinal degeneration

Inherited retinal degenerations (IRDs) are a group of genetic disorders that lead to progressive vision loss as the light-sensing cells of the eye-the photoreceptors-die due to mutations in genes needed for their function and survival.

23 May 2025

FOXP4 gene variants reveal new genetic link to long COVID risk

Researchers have identified genetic variants in the FOXP4 gene that significantly increase the risk of developing long COVID, independently of COVID-19 severity. The study also reveals that ancestry, smoking, and other factors contribute to the complex genetics of long COVID.

23 May 2025

Study uncovers first proof of introners jumping between species

DNA is the genetic code that provides the biological instructions for every living species, but not every bit of DNA helps the species survive. Some pieces of DNA are more like parasites, along for the ride and their own survival.

22 May 2025

Unlocking the secrets of human longevity and healthy aging

Human healthy aging and longevity are complex phenomena influenced by a dynamic interplay of genetic, epigenetic, metabolic, immune, and environmental factors.

22 May 2025

Cysteine depletion triggers rapid weight loss in mice

Mice genetically engineered to lack the ability to make the amino acid cysteine, and fed a cysteine-free diet, lost 30 percent of their body weight in just one week, a new study shows.

22 May 2025

Insulin resistance in the brain may link Alzheimer’s and epilepsy

Researchers at the University of São Paulo (USP) in Brazil have succeeded in showing, in an animal model, that the process of insulin resistance in the brain affects both Alzheimer's disease and epilepsy and may be a linking factor between the two diseases.

22 May 2025

New gene delivery systems can reach cells in the brain and spinal cord with exceptional accuracy

Research teams funded by the National Institutes of Health (NIH) have created a versatile set of gene delivery systems that can reach different neural cell types in the human brain and spinal cord with exceptional accuracy.

21 May 2025

New study links fetal mutations to early pregnancy loss

In a study published in Nature today "Sequence diversity lost in early pregnancy," scientists from deCODE genetics, a subsidiary of Amgen, estimate that around one in 136 pregnancies are lost due to new mutations in the fetus.

21 May 2025