Dysbiosis News and Research

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Dysbiosis is a condition caused by an imbalance in the bacterial community (microbiome) of the human gut. Dysbiosis disrupts the ecoystsem of the gut, resulting in symptoms such as diarrhea, constipation, bloating, and indigestion, among others.

Eating more ultra-processed food links depression and diabetes

New research links ultra-processed food intake to increased diabetes risk in individuals with depression, highlighting the need for healthier dietary choices.

30 Jul 2025

How a leaky gut could be putting your heart at risk

Researchers reviewed recent studies showing that gut dysbiosis contributes to heart failure by weakening the gut barrier, enabling harmful metabolites like TMAO to trigger inflammation and cardiac damage. The review highlights a bidirectional “gut-heart axis” and points to new avenues for dietary and microbial therapies.

28 Jul 2025

Probiotic bacteria found to reshape cell behavior in vitro

This study reveals how probiotic bacteria directly influence brain cell function, highlighting gut-brain communication and potential therapeutic applications.

23 Jul 2025

Restricted diet triggers drop in microbial diversity without convergence

According to a recent exploratory study published in eGastroenterology, the answer is more complex than expected. Researchers from KU Leuven and collaborating institutions conducted a tightly controlled dietary intervention, known as the "Oatmeal Study", to examine whether restricting food variety could induce convergence in the gut microbiota across individuals.

22 Jul 2025

Boosting gut-friendly foods may slow biological aging, large US study finds

Higher scores on a dietary index linked to gut microbiota health are associated with slower biological aging in US adults, according to a large cross-sectional NHANES study. The findings suggest that improving diet quality for gut microbial diversity may help reduce age-related disease risk.

20 Jul 2025

Combination of dysbiosis, OTUD3 gene mutations, and STING signaling linked to ulcerative colitis severity

Ulcerative colitis (UC) causes misery for millions worldwide. It affects the large intestine, causing pain, cramping, and frequent bowel movements with bloody diarrhea.

18 Jul 2025

Parental cholesterol predicts asthma severity in children

Parental metabolic health influences childhood asthma severity, with paternal cholesterol showing modest protective effects against exacerbating symptoms.

18 Jul 2025

Study reveals altered gut microbiota profiles in elderly patients with acute hepatitis E

Gut dysbiosis has been reported in severe liver diseases. However, information on the impact of hepatitis E virus infection on the gut microbiota, and the association between enteric microbiota disturbances and acute hepatitis E (AHE), is limited, particularly in elderly patients with AHE (AHE-elderly).

8 Jul 2025

Oral lysozyme can restore healthy gut balance and reverse signs of vascular aging

A study reveals that lysozyme (LYZ) plays a pivotal role in age-related blood vessel inflammation by influencing gut bacteria.

8 Jul 2025

Synthetic Biology and the Pursuit of Living Diagnostics and Therapeutics

In this interview, Professor James J. Collins, founder of the field of Synthetic Biology, discusses his journey to founding the field of synthetic biology and the potential of living diagnostics.

From Pittcon 7 Jul 2025

Eating habits directly influence vaginal microbiome, research finds

A cross-sectional study of young Italian women found that higher intake of animal protein and alcohol is associated with vaginal microbiota dysbiosis, while linolenic acid (a plant-based omega-3) and dietary fiber support beneficial Lactobacillus communities.

7 Jul 2025

Vaginal microbiome fights back against stubborn BV infections

Vaginal microbiome-drug interactions affect antibiotic treatment for bacterial vaginosis, emphasizing the need for personalized approaches to enhance efficacy.

3 Jul 2025

Spaceflight exposes astronauts to hidden threats in their gut

This review highlights how the unique stressors of space travel, radiation, microgravity, and circadian disruption impact astronauts’ gut microbiomes, with potential consequences for their mood, cognition, and immunity. The authors call for targeted microbiome monitoring and dietary interventions to protect astronaut mental health on future missions.

1 Jul 2025

Gut microbiota signatures predict gestational diabetes in first trimester

A new study has identified early-pregnancy gut microbiota signatures associated with the development of gestational diabetes mellitus, a metabolic disorder that carries substantial risks to both maternal and fetal health.

1 Jul 2025

Are sweeteners really making our children’s diets healthier?

Higher consumption of low-calorie sweetened (LCS) products among UK children was not consistently linked to reduced free sugar intake, and may reflect less healthy overall dietary patterns. Over 11 years, improvements in dietary quality were slowest among those consuming the most LCS products.

29 Jun 2025

Do spicy foods help or hurt your gut health?

Capsaicin, the spicy compound in chili peppers, not only influences inflammation, metabolism, and cancer risk but also shapes the gut microbiome in complex, context-dependent ways. This comprehensive review highlights both the therapeutic promise and potential risks of capsaicin, calling for deeper research into its microbiome-mediated effects.

26 Jun 2025

Missing gut bacteria in US babies triples allergy and eczema risk

US infants lacking Bifidobacterium in their gut microbiome face significant changes in microbial composition, metabolic function, and immune-related health risks. This large, nationally representative study links early-life Bifidobacterium deficits to a three-fold increase in eczema, allergy, or asthma by age two.

25 Jun 2025

Gut microbe emerges as a promising tool in the fight against COVID-19

Researchers found that Akkermansia muciniphila boosts lung-specific antiviral immunity against SARS-CoV-2 in mice by modulating the gut–lung axis. This commensal gut bacterium shows promise as a potential biomarker and biotherapeutic candidate for COVID-19 and other respiratory infections.

25 Jun 2025

Excess trace metal levels may trigger gestational diabetes

Excess micronutrients in early pregnancy may raise gestational diabetes risks. Study links essential metal levels to GDM onset, urging a rethink on supplements.

24 Jun 2025

Genes may determine how early life exposures shape the gut microbiome

Early nutritional and antibiotic exposures affect adult gut microbiota, with genetic background and parent-of-origin significantly influencing outcomes.

19 Jun 2025