ACE Inhibitors News and Research

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ACE inhibitors act to reduce hypertension by interfering with the conversion of angiotensin I to artery-constricting angiotensin II. Blocking the production of angiotensin II results in arterial vasodilation and an accompanying reduction in blood pressure. ACE inhibitors currently are recommended as first-line therapy for hypertension in certain patient populations, because of their safety and efficacy.

Crateagus extract postpones cardiac events in patients with congestive heart failure

An herbal medicinal substance, Crataegus Extract WS:1442, safely extends the lives of congestive heart failure patients already receiving pharmacological treatment for the disease, according to a study presented at the American College of Cardiology's 56th Annual Scientific Session.

30 Mar 2007

Blood pressure drug shows potential as lung cancer treatment

A hormone that is important in the control of blood pressure also shrinks lung cancer tumors in mice, suggesting a new way to prevent or treat the deadly cancer, according to scientists at Wake Forest University School of Medicine.

19 Mar 2007

Beta-blockers should not be a doctor's first choice for treating high blood pressure

Beta-blocker drugs such as Tenormin, Inderal and Lopressor should not be a doctor's first choice for treating high blood pressure, according to a large new review of studies.

20 Feb 2007

Value based insurance design

Like a one-size-fits-all shirt that doesn't fit anyone very well, American health insurance plans charge every person the same out of pocket cost for medical services - regardless of their effect on a person's health.

30 Jan 2007

Angioplasty no better than drugs for heart attack victims who delay treatment

In what will come as a surprise to many doctors, researchers in the United States how found that contrary to current belief, heart attack survivors with mild or no symptoms who wait three days or more to seek medical help, will achieve little benefit from the procedures used to open clogged arteries.

15 Nov 2006

Diabetes risk down three times with newer hypertension drugs

According to researchers patients given a mix of modern blood pressure drugs are one-third less likely to develop diabetes than those on older pills.

7 Sep 2006

Immunotherapy for heart failure

World Congress of Cardiology Report - Heart failure (HF) is a complex, progressive clinical syndrome that can result from any structural or functional cardiac disorder, such as coronary artery disease or hypertension (high blood pressure), which impairs the ability of the heart to function properly as a pump.

5 Sep 2006

One of the largest Japanese cardiovascular trials confirms angiotensin receptor blockade protects people who have a wide range of cardiovascular diseases

The first controlled large-scale intervention trial of angiotensin receptor blockade in Japanese patients has confirmed that the cardiovascular protective effects of the drug valsartan is greater than to those seen with other therapies giving the same level of blood pressure control.

5 Sep 2006

Women receive lower-quality heart attack care than men

A new study shows that a puzzling gap between the sexes persists in hospital care for heart attack patients, despite specific efforts by hospitals to improve the way they treat all patients immediately after a heart attack.

10 Jul 2006

Hospital quality measures do not fully account for the variation in hospital death rates for heart attack patients

Hospital quality measures do not fully account for the variation in hospital death rates for heart attack patients, according to a study in the July 5 issue of Journal of the American Medical Association.

4 Jul 2006

New guidelines for treating high blood pressure discounts beta-blockers

Drug treatment for high blood pressure is set to undergo a major shake-up after new guidance was issued for the NHS.

28 Jun 2006

Popular hypertension drugs triple the risk of birth defects

A study by American researchers has found that certain widely used hypertension drugs, once considered safe in the early stages of pregnancy, can almost triple the risk of birth defects.

8 Jun 2006

Blood pressure drugs associated with reduced risk of cancers

Thousands of individuals currently taking angiotension converting enzyme (ACE) inhibitors, a type of medication commonly used to lower blood pressure, may be doing more than treating their hypertension.

31 May 2006

Trandolapril and verapamil reduce risk of developing diabetes in Hispanic patients

The combination of drugs traditionally used to control blood pressure might not be ideal for Hispanic patients, University of Florida researchers warn.

23 May 2006

MRI provides an early alert for polycystic kidney disease

A new method using magnetic resonance imaging (MRI) accurately tracks structural changes that predict functional changes earlier than standard blood and urine tests in people with autosomal dominant polycystic kidney disease (PKD).

17 May 2006

Smokers more likely to receive jolt from defibrillators

If some patients with heart disease don't take their doctor's advice to quit smoking, they are probably going to get "shocking" reminders.

8 May 2006

Only 43 percent of older people with diabetes receive medicines that could protect their heart and kidneys

...despite the fact that virtually all of them could benefit from those drugs, a new University of Michigan study finds. And even among those with the most to gain from the medicines, the rate of use barely reaches 53 percent.

18 Apr 2006

Angiotension-converting enzyme inhibitors may reduce cardiovascular risk

Angiotension-converting enzyme (ACE) inhibitors, medications commonly used to treat hypertension (high blood pressure), may reduce cardiovascular risk and the risk of death in patients with coronary artery disease, according to a new analysis of previously conducted clinical trials reported in the Archives of Internal Medicine.

13 Apr 2006

Enzyme released by cardiac mast cells during heart attack contributes to arrhythmia

In times of cardiac crisis, mast cells in the heart secrete a powerful enzyme, renin, that indirectly triggers dangerous arrhythmias, according to a team of researchers at the Weill Medical College of Cornell University in New York City.

4 Apr 2006

New model is able to accurately predict survival for patients with heart failure

A new model developed at the University of Washington provides an accurate estimate of one-, two-, and three-year survival rates and average years of survival for patients with heart failure.

15 Mar 2006