ACE Inhibitors News and Research

RSS

ACE inhibitors act to reduce hypertension by interfering with the conversion of angiotensin I to artery-constricting angiotensin II. Blocking the production of angiotensin II results in arterial vasodilation and an accompanying reduction in blood pressure. ACE inhibitors currently are recommended as first-line therapy for hypertension in certain patient populations, because of their safety and efficacy.

Beta-blockers reduce mortality in patients with heart failure and moderate kidney dysfunction

Beta-blockers remain effective for preventing death in heart failure with reduced ejection fraction (HFrEF) and sinus rhythm, even in patients with moderate or moderately-severe kidney dysfunction, according to late breaking research presented in a Hot Line Session today at ESC Congress 2019 together with the World Congress of Cardiology.

3 Sep 2019

ESC guidelines highlight detrimental impact of pollution, noise on patients with chronic coronary syndromes

The detrimental impact of pollution and noise on patients with chronic coronary syndromes is highlighted for the first time in European Society of Cardiology (ESC) Guidelines published online today in European Heart Journal, and on the ESC website.

31 Aug 2019

FDA approves novel device to treat symptoms associated with advanced heart failure

The U.S. Food and Drug Administration today approved the Barostim Neo System for the improvement of symptoms in patients with advanced heart failure who are not suited for treatment with other heart failure devices, such as cardiac resynchronization therapy.

18 Aug 2019

Women more likely to be under-treated for heart disease

The large-scale analysis carried out by La Trobe University researchers and published in Heart found that many Australians living with CHD are under-prescribed recommended medications, are not monitored for major risk factors and have treatments that do not achieve recommended goals.

23 Jul 2019

Blood pressure medication associated with increased risk of diverticulosis

A type of blood pressure lowering medication, called a calcium-channel blocker, may be linked with an increased risk of a type of bowel condition called diverticulosis.

3 Jul 2019

Chemotherapy can wreak havoc on the heart

Cheryl Krafft was diagnosed with an aggressive form of non-Hodgkin's lymphoma and was put on a very high-powered chemotherapy regimen to rid her body of the cancer. What she was not counting on was the chemotherapy causing another equally deadly problem.

21 Jun 2019

Research paves way for new treatment to protect people from cardiovascular disease

New University of Alberta research is paving the way for the first medical treatment to help protect people from cardiovascular disease by boosting the body's natural defenses.

17 Jun 2019

Antihypertensive drug use linked with reduction in dementia risk

Various clinical trials indicate what effects can be expected from standardized intervention programs on the basis of existing evidence.

3 Jun 2019

Study shows improvements in cardiovascular risk for women developing Type 2 diabetes despite prescription bias

A Diabetes UK-funded study suggests that Type 2 diabetes leads to a smaller increase in the risk of cardiovascular disease for women today than it has done in the past.

15 Apr 2019

New device approved by FDA for treating patients with moderate-to-severe heart failure

The U.S. Food and Drug Administration today approved the Optimizer Smart system for treating patients with chronic, moderate-to-severe heart failure who are not suited for treatment with other heart failure devices such as cardiac resynchronization therapy to restore a normal timing pattern of the heartbeat.

22 Mar 2019

Research: Pure omega-3 prescription drug significantly reduces the occurrence of ischemic events

Taking a high dose of icosapent ethyl--a pure and stable prescription form of the omega-3 fatty acid known as EPA--significantly reduces the occurrence of first, subsequent and total ischemic events, including heart attacks, strokes and related deaths, among people at high cardiovascular risk despite already being on statin therapy, according to research presented at the American College of Cardiology's 68th Annual Scientific Session.

19 Mar 2019

Two-drug combinations containing calcium channel blocker significantly lowers BP

In the largest randomized controlled trial of treatment for high blood pressure ever conducted in sub-Saharan Africa, two frontline two-drug combinations that included the long-acting calcium channel blocker, amlodipine, were able to drive down blood pressure levels more than a third two-drug combination that did not include amlodipine, according to research presented at the American College of Cardiology's 68th Annual Scientific Session.

19 Mar 2019

Novel treatment targeting fibroblasts may prevent heart failure after heart attack

Heart attack survivors are at greater risk of developing heart failure, a chronic condition in which more than half of those diagnosed will die within five years.

5 Mar 2019

Study finds underutilization of aspirin to prevent colorectal cancer in high risk patients

Colorectal cancer is the third most common cause of cancer deaths in the United States and advanced colorectal polyps are a major risk factor.

7 Feb 2019

Low-salt diet may be more beneficial for females than males

A low-salt diet may be more beneficial in lowering blood pressure in females than males, report scientists who found that while actual salt retention isn't higher in females, there is still an effect that drives pressure up.

11 Dec 2018

Drug therapy can improve outcomes for acutely ill heart patients

A drug therapy used for patients with chronic heart failure also improves markers of poor prognosis in individuals who are hospitalized with acute heart failure, new Yale-led research shows.

12 Nov 2018

UA professor wins NIH grant to advance research in preventing heart failure

A University of Arizona College of Medicine - Phoenix researcher has received a $393,493 grant from the National Institutes of Health to further her research in reducing the risk of heart failure in patients with high blood pressure.

1 Nov 2018

New statement provides detailed overview of how to diagnose, treat resistant hypertension

Resistant hypertension affects 12 percent to15 percent of patients treated for high blood pressure according to a new scientific statement from the American Heart Association.

14 Sep 2018

Hypertension drugs may be used to preserve memory of lupus patients

Researchers from The Feinstein Institute for Medical Research have discovered that the activation of brain cells called microglia likely contributes to the memory loss and other cognitive impairments suffered by many patients with systemic lupus erythematosus.

5 Sep 2018

$Entresto drug can be initiated early and safely in heart failure patients with reduced ejection fraction$

Entresto drug can be initiated early and safely in heart failure patients with reduced ejection fraction

Data from the TRANSITION study presented today at the European Society of Cardiology Congress in Munich, Germany has shown that Entresto® can be initiated early and safely in a wide range of heart failure patients with reduced ejection fraction who have been stabilized after hospitalization due to an acute heart failure episode.

25 Aug 2018