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Study explores the effect of COVID-19 on platelet function

A new study posted in the pre-print server bioRxiv* aimed to analyze the impact of COVID-19 on platelet proteome and relate the functional responses of platelets and the formation of platelet-neutrophil aggregate in hospitalized COVID-19 patients.

17 Oct 2022

High TNF receptors levels could predict COVID-19 mortality and disease severity

High levels of TNFR might successfully predict the increased severity of COVID-19.

16 Oct 2022

Transition in the management of COVID-19

A review of the current approaches to managing COVID-19, including diagnostic, therapeutic, and preventive measures.

16 Oct 2022

Review on Panax ginseng therapeutic efficacy for COVID-19-associated neurological diseases

In a new study, researchers discussed the therapeutic potential of Panax ginseng for COVID-19 (coronavirus disease 2019)-induced neurological diseases.

14 Oct 2022

Researchers develop an HERV-enveloped recombinant baculoviral DNA vaccine against SARS-CoV-2

Researchers developed a human endogenous retrovirus (HERV)-enveloped recombinant baculoviral DNA vaccine to target the SARS-CoV-2 Delta variant, and tested its cross-protection efficacy using mice models.

13 Oct 2022

Study explores cell signaling dysregulation and COVID-19 severity

Researchers assessed the impact of dysregulation in cell signaling events on coronavirus disease 2019 (COVID-19) severity.

12 Oct 2022

Metformin reduces risk of severe COVID-19 in diabetic patients

A new study determines whether antidiabetic agents can reduce complications in COVID-19 patients with diabetes.

10 Oct 2022

Chronic liver disease in COVID-19 patients

A recent study summarizes the clinical outcomes of COVID-19 patients with chronic liver disease.

10 Oct 2022

UMSOM researchers identify how multiple genes of SARS-CoV-2 affect disease severity

University of Maryland School of Medicine researchers have identified how multiple genes of SARS-CoV-2 affect disease severity, which could lead to new ways in how we develop future vaccines or develop newer treatments.

7 Oct 2022

Silver nanoparticle and polyurethane composite provides potential coating options to limit fomite transmission of SARS-CoV-2

In a new study, researchers synthesized and evaluated a silver and polyurethane nanocomposite surface coating material that exhibits antiviral activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

7 Oct 2022

Histone mimicry by SARS-CoV-2 protein disrupts epigenetic regulation of host cells

Researchers demonstrated that the SARS-CoV-2 protein functions as a histone mimic to disrupt the epigenetic regulation of host cells.

7 Oct 2022

Neonatal mice-based model established that allows for the transmission of clinical SARS-CoV-2 isolates

Researchers established a neonatal mice model that enabled SARS-CoV-2 transmission.

7 Oct 2022

Study suggests an immunological benefit of combining previous natural infection with vaccination against COVID-19 using a combination of different vaccine platforms

Researchers explored SARS-CoV-2-targeted immune responses among COVAC1 participants who received a novel saRNA vaccine followed by the mRNA BNT162b2 vaccine BNT162b2 vaccine, with or without prior COVID-19 history.

7 Oct 2022

Clinical trials of novel COVID-19 vaccine developed in Brazil to begin soon

Testing on humans of a novel COVID-19 vaccine developed in Brazil will begin this year. It performed well in animal trials, as reported in an article published in August in Nature Communications.

6 Oct 2022

Three-dimensional in vitro model to reproduce COVID-19-induced endothelial dysfunction

In a new study, researchers developed a three-dimensional (3D) in vitro tissue model to assess the effects of SARS-CoV-2 on the vascular endothelial cells.

5 Oct 2022

Yeast display used to generate SARS-CoV-2 RBD-specific nanobodies

Researchers engineered biparatopic nanobodies against SARS-CoV-2.

5 Oct 2022

Study shows SARS-CoV-2 infects human adipose tissue and undergoes productive infection in fat cells

Researchers demonstrated infection of human adipose tissue by SARS-CoV-2.

5 Oct 2022

Omicron reduces host antibody response by lower B-cell antigenicity

A new study explores the functional relevance of some Omicron mutations in terms of their ability to escape neutralizing antibody responses.

4 Oct 2022

What are the challenges of COVID-19 vaccination and herd immunity?

A new study reviewed the challenges of coronavirus disease 2019 (COVID-19) vaccination and herd immunity.

4 Oct 2022

How COVID-19 affects the female reproductive system

A new review in the Biology of Reproduction journal analyzed the relationship between the immune system and the female reproductive system while focusing on the effects of COVID-19-associated immune responses on the reproductive system. The study searched PubMed to identify peer-reviewed literature in English up to May 2022 and finally included 83 studies.

3 Oct 2022

ACE2 News and Research

Study explores the effect of COVID-19 on platelet function

High TNF receptors levels could predict COVID-19 mortality and disease severity

Transition in the management of COVID-19

Review on Panax ginseng therapeutic efficacy for COVID-19-associated neurological diseases

Researchers develop an HERV-enveloped recombinant baculoviral DNA vaccine against SARS-CoV-2

Study explores cell signaling dysregulation and COVID-19 severity

Metformin reduces risk of severe COVID-19 in diabetic patients

Chronic liver disease in COVID-19 patients

UMSOM researchers identify how multiple genes of SARS-CoV-2 affect disease severity

Silver nanoparticle and polyurethane composite provides potential coating options to limit fomite transmission of SARS-CoV-2

Histone mimicry by SARS-CoV-2 protein disrupts epigenetic regulation of host cells

Neonatal mice-based model established that allows for the transmission of clinical SARS-CoV-2 isolates

Study suggests an immunological benefit of combining previous natural infection with vaccination against COVID-19 using a combination of different vaccine platforms

Clinical trials of novel COVID-19 vaccine developed in Brazil to begin soon

Three-dimensional in vitro model to reproduce COVID-19-induced endothelial dysfunction

Yeast display used to generate SARS-CoV-2 RBD-specific nanobodies

Study shows SARS-CoV-2 infects human adipose tissue and undergoes productive infection in fat cells

Omicron reduces host antibody response by lower B-cell antigenicity

What are the challenges of COVID-19 vaccination and herd immunity?

How COVID-19 affects the female reproductive system

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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