Acetaminophen News and Research

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The pain-reliever acetaminophen (also known as paracetomol) is one of the best-selling over-the-counter medications, used by more than 200 million Americans a year. It is sold under many brand names, including Tylenol, and is an ingredient in nearly 200 medications, both over-the-counter (such as Excedrin, Midol, NyQuil, and Sudafed) and prescription (such as Vicodin).

Wraser purchases Trezix oral capsule product from e5 Pharma

WraSer Pharmaceuticals, LLC (WraSer) announced that it has purchased the Trezix® Oral Capsule product from e5 Pharma, LLC. With the purchase, WraSer is granted full rights to market and distribute Trezix® in the United States.

20 Aug 2009

Medication safety program on safe prescribing procedures for narcotic drugs launched

Warnings by the Food and Drug Administration (FDA) and increasing misuse and overdoses are telling reminders of the dangers pain medications can present. A recent study reveals that one in 10 high school students have tried opioid drugs and the prevalence of young adults using narcotics for non-medical use is the highest in 15 years.

20 Aug 2009

Accidental childhood poisonings mostly due to medicines

More than two-thirds of all emergency department visits for childhood poisoning involve prescription and over-the-counter medications, more than twice the rate of poisonings from consumer products, reports a new study from the Centers for Disease Control and Prevention (CDC).

4 Aug 2009

Scientists report new process for producing potentially safer form of acetaminophen

Scientists in Louisiana are reporting development of a process for producing large batches of a new and potentially safer form of acetaminophen, the widely used pain-reliever now the source of growing concern over its potentially toxic effects on the liver.

15 Jul 2009

Discovery of genetic marker linked to the risk of acetaminophen-induced liver injury

Acetaminophen (Tylenol and generics) is one of the most commonly used over-the-counter drugs in the United States. While generally safe, acetaminophen is known to cause severe liver injury if taken in high doses. But likely due to genetics, even the recommended dose can induce serious liver damage in a significant number of people.

4 May 2009

New, more effective and less costly method for testing drugs for potential toxicity

Adverse reactions to drugs represent one of the leading causes of death in the United States. But there may be a way to predict who is most likely to suffer a toxic side effect to a drug before they have even taken it.

4 May 2009

Early treatment for hepatitis C offers a good chance of a cure

Australian researchers say as many as 70% of hepatitis C carriers can possibly be cured of the disease with early treatment - this is excellent news as hepatitis C, if left untreated can lead to serious liver disease.

22 Apr 2009

Oxycodone effective against shingles pain

The painkiller oxycodone is effective at treating the acute pain of shingles, an illness that often causes severe pain which can become long-lasting and sometimes even permanent.

26 Mar 2009

Gleevec reduces risk of cancer returning in patients with life-threatening gastrointestinal stromal tumors

Data published online and in an upcoming print issue of The Lancet show that Gleevec (imatinib mesylate) tablets, when taken after surgery, substantially reduces the rate of recurrence of Kit-positive gastrointestinal stromal tumors (GIST) compared with placebo.

20 Mar 2009

Cherries show promise in osteoarthritis pain relief

For the estimated 27 million Americans who suffer from osteoarthritis, pain relief may come with a cherry on top.

20 Mar 2009

Clinical practice guidelines for osteoarthritis of the knee

Osteoarthritis (OA) is known as the "wear and tear" arthritis. It can affect any joint in the body particularly after years of use.

26 Feb 2009

Aspirin counteracts new mechanisms of acetaminophen-induced liver damage

Overdoses of acetaminophen (also known as paracetamol) account for most drug overdoses in a number of countries, including the United States. Such overdoses damage the liver, causing acute liver failure, which can be fatal.

27 Jan 2009

Aspirin shown to help prevent liver damage

According to scientists at Yale University ordinary aspirin may help prevent liver damage in millions of people suffering from the side effects of common drugs, alcohol abuse and obesity-related liver disease.

27 Jan 2009

Sun Pharmaceutical receives FDA approvals for 4 generics

Sun Pharmaceutical Industries Ltd. announced that together with its subsidiaries, it has received final approval from U.S. FDA for several Abbreviated New Drug Applications (ANDA).

7 Jan 2009

Acute gastric injury due to high-dose analgesics?

Analgesics, NSAIDs and acetaminophen, are commonly used for the relief of fever, headaches, and other minor aches and pains.

30 Dec 2008

FDA advisory committee to dscuss PMA for Genzyme's Synvisc-One

Genzyme Corporation has announced that its Premarket Approval (PMA) application supplement for Synvisc-One (hylan G-F 20) will be discussed this Tuesday, December 9th, at a public meeting of the FDA's Orthopaedic and Rehabilitation Devices Advisory Committee in Gaithersburg, Maryland.

8 Dec 2008

Antibiotics causing most drug-induced liver injury

Antibiotics are the single largest class of agents that cause idiosyncratic drug-induced liver injury (DILI), reports a new study in Gastroenterology, an official journal of the American Gastroenterological Association (AGA) Institute.

1 Dec 2008

Medications containing barbiturates or narcotics may make migraine worse

A team of researchers led by investigators at the Albert Einstein College of Medicine of Yeshiva University has determined that certain commonly-prescribed medications may have the unintended consequence of increasing the frequency of migraine attacks.

18 Nov 2008

Pain-relieving gel makes mammograms a less painful experience

Women dreading the prospect of another painful mammogram can, according to researchers, relieve some of the breast discomfort by using a pain-relieving gel.

16 Sep 2008

Anti-inflammatory drugs may mask prostate cancer marker

Regular use of nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin and ibuprofen, may reduce serum levels of the prostate biomarker, PSA (prostate specific antigen), and hence may alter the detection of prostate cancer in individuals who take these medications.

14 Sep 2008