The pain-reliever acetaminophen (also known as paracetomol) is one of the best-selling over-the-counter medications, used by more than 200 million Americans a year. It is sold under many brand names, including Tylenol, and is an ingredient in nearly 200 medications, both over-the-counter (such as Excedrin, Midol, NyQuil, and Sudafed) and prescription (such as Vicodin).
Acetaminophen is a common pain reliever found in every pharmacy. However, it is also the No. 1 cause of acute liver failure in the United States. In the liver, acetaminophen is converted into a new compound that covalently binds to proteins at an amino acid called cysteine.
Taking a low-dose aspirin daily may help women lower their risk of developing ovarian cancer. A new study co-led by Moffitt Cancer Center found that women who reported taking a low-dose aspirin every day had a 23 percent lower risk of ovarian cancer compared to nonaspirin users.
Seattle Genetics, Inc. and Takeda Pharmaceutical Company Limited announced today that the phase 3 ECHELON-2 clinical trial met its primary endpoint.
Emerging viruses such as Ebola, SARS and swine flu are familiar sounding, yet seemingly distant diseases to many Americans. But that's not the case with Chikungunya, a mosquito-borne virus that recently struck close to home and has proven deadly for the elderly.
Seattle Genetics, Inc. today announced that its collaborator, Takeda Pharmaceutical Company Limited, has received approval from the Japanese Ministry of Health, Labour and Welfare for ADCETRIS (brentuximab vedotin) in combination with doxorubicin, vinblastine and dacarbazine as a frontline treatment option for CD30-positive Hodgkin lymphoma patients in Japan.
Before surgeon Emily Penman, M.D., begins a mastectomy or lumpectomy, her lightly sedated patient receives a nerve block, an injection of medicine to control pain after surgery.
Tandem Diabetes Care, Inc. , a medical device company and manufacturer of the only touchscreen insulin pumps with continuous glucose monitoring (CGM) integration, today announced its launch of the t:slim X2 Insulin Pump with Basal-IQ™ Technology, a predictive low glucose suspend (PLGS) feature designed to help reduce the frequency and duration of low glucose events (hypoglycemia).
The U.S. Food and Drug Administration today approved Onpattro (patisiran) infusion for the treatment of peripheral nerve disease (polyneuropathy) caused by hereditary transthyretin-mediated amyloidosis (hATTR) in adult patients.
To curb the use of opioids after major elective operations and prevent these pain relievers from falling into the wrong hands, surgeons at the University of Michigan developed prescribing recommendations based on published medical evidence for one operation, gall bladder removal, and then discovered a spillover effect that led them to prescribe roughly 10,000 fewer pills for other major operations, according to study results appearing as an "article in press" on the website of the Journal of the American College of Surgeons ahead of print.
Researchers from Australia's Curtin University have developed a simple pill that could be used to treat methamphetamine addicts. It would soon be tried in a clinical trial to prove its efficacy and utility said the researchers.
The latest issue in the From Policy to Practice report series from The Gerontological Society of America addresses recent labeling changes for OTC analgesics and highlights important considerations when recommending the use of these products in older adults.
Cuts from a sharp knife or a piece of glass are very common. They often occur while people are preparing food, washing dishes or even crafting. All it takes is a slip of the knife or a dish breaking, and suddenly there's blood.
What's the right painkiller prescription to send home with a patient after gallbladder surgery or a cesarean section?
Intravenous acetaminophen is no more effective than oral acetaminophen for patients undergoing colorectal procedures, Mount Sinai researchers report in a first-of-its-kind study.
Dr. Robert Zura, Professor and Chair of Orthopaedic Surgery at LSU Health New Orleans School of Medicine, was part of a research team reporting that not only may opioid use increase the risk of bone fractures, but opioids may also impair healing.
Rutgers School of Public Health Professor Dr. Emily Barrett, PhD, and North Carolina State University Professor Dr. Heather Patisaul, PhD, have guest edited a special issue of the journal Hormones and Behavior.
Chikungunya virus is a growing threat to the United States and other regions of the world as the mosquito that carries the virus expands its reach. Telltale symptoms of chikungunya infection are fever and joint pain that last about a week.
Children who underwent cardiac surgery were less likely to develop acute kidney injury if they had been treated with acetaminophen in the first 48 hours after their procedures, according to a Vanderbilt study just published in JAMA Pediatrics.
LogicBio Therapeutics, Inc., a genetic medicine company founded to develop safe medicines with lasting therapeutic benefit for children with life-threatening diseases, today announced it will be presenting data on the company's technology and robust preclinical pipeline at the annual meeting of the American Society of Gene & Cell Therapy at the Hilton Chicago, from May 16-19, 2018.
An estimated 45 percent of people are at risk of developing knee osteoarthritis (OA) in their lifetime. According to a network meta-analysis research article published in the May 1, 2018 issue of the Journal of the American Academy of Orthopaedic Surgeons, the nonsteroidal anti-inflammatory drug naproxen was ranked most effective in individual knee OA treatment for improving both pain and function, and is considered a relatively safe and low-cost treatment method.