Acetaminophen News and Research

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The pain-reliever acetaminophen (also known as paracetomol) is one of the best-selling over-the-counter medications, used by more than 200 million Americans a year. It is sold under many brand names, including Tylenol, and is an ingredient in nearly 200 medications, both over-the-counter (such as Excedrin, Midol, NyQuil, and Sudafed) and prescription (such as Vicodin).

Researchers uncover how common pain reliever causes liver failure

Acetaminophen is a common pain reliever found in every pharmacy. However, it is also the No. 1 cause of acute liver failure in the United States. In the liver, acetaminophen is converted into a new compound that covalently binds to proteins at an amino acid called cysteine.

11 Oct 2018

Low-dose aspirin use associated with reduced ovarian cancer risk

Taking a low-dose aspirin daily may help women lower their risk of developing ovarian cancer. A new study co-led by Moffitt Cancer Center found that women who reported taking a low-dose aspirin every day had a 23 percent lower risk of ovarian cancer compared to nonaspirin users.

4 Oct 2018

Phase 3 ECHELON-2 clinical trial evaluating ADCETRIS plus CHP meets primary endpoint

Seattle Genetics, Inc. and Takeda Pharmaceutical Company Limited announced today that the phase 3 ECHELON-2 clinical trial met its primary endpoint.

1 Oct 2018

Immunologist to study how Chikungunya causes devastating effects in older adults

Emerging viruses such as Ebola, SARS and swine flu are familiar sounding, yet seemingly distant diseases to many Americans. But that's not the case with Chikungunya, a mosquito-borne virus that recently struck close to home and has proven deadly for the elderly.

25 Sep 2018

ADCETRIS drug receives approval in Japan as frontline treatment option for Hodgkin lymphoma

Seattle Genetics, Inc. today announced that its collaborator, Takeda Pharmaceutical Company Limited, has received approval from the Japanese Ministry of Health, Labour and Welfare for ADCETRIS (brentuximab vedotin) in combination with doxorubicin, vinblastine and dacarbazine as a frontline treatment option for CD30-positive Hodgkin lymphoma patients in Japan.

24 Sep 2018

Christiana Care Health System successfully reduces opioid prescriptions

Before surgeon Emily Penman, M.D., begins a mastectomy or lumpectomy, her lightly sedated patient receives a nerve block, an injection of medicine to control pain after surgery.

21 Aug 2018

Tandem Diabetes Care introduces t:slim X2 Insulin Pump with Basal-IQ Technology in the US

Tandem Diabetes Care, Inc. , a medical device company and manufacturer of the only touchscreen insulin pumps with continuous glucose monitoring (CGM) integration, today announced its launch of the t:slim X2 Insulin Pump with Basal-IQ™ Technology, a predictive low glucose suspend (PLGS) feature designed to help reduce the frequency and duration of low glucose events (hypoglycemia).

17 Aug 2018

FDA approves first targeted RNA-based treatment for rare, fatal genetic disease

The U.S. Food and Drug Administration today approved Onpattro (patisiran) infusion for the treatment of peripheral nerve disease (polyneuropathy) caused by hereditary transthyretin-mediated amyloidosis (hATTR) in adult patients.

10 Aug 2018

Study shows spillover effect of evidence-based opioid prescribing for major procedures

To curb the use of opioids after major elective operations and prevent these pain relievers from falling into the wrong hands, surgeons at the University of Michigan developed prescribing recommendations based on published medical evidence for one operation, gall bladder removal, and then discovered a spillover effect that led them to prescribe roughly 10,000 fewer pills for other major operations, according to study results appearing as an "article in press" on the website of the Journal of the American College of Surgeons ahead of print.

27 Jul 2018

A simple pill for meth addicts on the cards

Researchers from Australia's Curtin University have developed a simple pill that could be used to treat methamphetamine addicts. It would soon be tried in a clinical trial to prove its efficacy and utility said the researchers.

18 Jul 2018

GSA's new publication provides support for safe use of OTC analgesics by older adults

The latest issue in the From Policy to Practice report series from The Gerontological Society of America addresses recent labeling changes for OTC analgesics and highlights important considerations when recommending the use of these products in older adults.

17 Jul 2018

Simple tips to treat minor cuts

Cuts from a sharp knife or a piece of glass are very common. They often occur while people are preparing food, washing dishes or even crafting. All it takes is a slip of the knife or a dish breaking, and suddenly there's blood.

10 Jul 2018

Doling out pain pills post-surgery: An ingrown toenail not the same as a bypass

What's the right painkiller prescription to send home with a patient after gallbladder surgery or a cesarean section?

22 Jun 2018

Study finds IV acetaminophen to be no more effective than oral counterpart for colectomy patients

Intravenous acetaminophen is no more effective than oral acetaminophen for patients undergoing colorectal procedures, Mount Sinai researchers report in a first-of-its-kind study.

19 Jun 2018

$Chronic use of opioids related to increased risk of fracture nonunion$

Chronic use of opioids related to increased risk of fracture nonunion

Dr. Robert Zura, Professor and Chair of Orthopaedic Surgery at LSU Health New Orleans School of Medicine, was part of a research team reporting that not only may opioid use increase the risk of bone fractures, but opioids may also impair healing.

18 Jun 2018

Special issue focuses on how endocrine-disrupting chemicals influence behavior

Rutgers School of Public Health Professor Dr. Emily Barrett, PhD, and North Carolina State University Professor Dr. Heather Patisaul, PhD, have guest edited a special issue of the journal Hormones and Behavior.

13 Jun 2018

Study finds molecular handle that chikungunya virus uses to enter into cells and cause arthritis

Chikungunya virus is a growing threat to the United States and other regions of the world as the mosquito that carries the virus expands its reach. Telltale symptoms of chikungunya infection are fever and joint pain that last about a week.

17 May 2018

Acetaminophen use helps reduce acute kidney injury risk in pediatric heart surgery patients

Children who underwent cardiac surgery were less likely to develop acute kidney injury if they had been treated with acetaminophen in the first 48 hours after their procedures, according to a Vanderbilt study just published in JAMA Pediatrics.

15 May 2018

LogicBio team to present data on preclinical effectiveness of GeneRide platform

LogicBio Therapeutics, Inc., a genetic medicine company founded to develop safe medicines with lasting therapeutic benefit for children with life-threatening diseases, today announced it will be presenting data on the company's technology and robust preclinical pipeline at the annual meeting of the American Society of Gene & Cell Therapy at the Hilton Chicago, from May 16-19, 2018.

14 May 2018

Nonsteroidal anti-inflammatory drug ranked to be most effective in treating knee OA

An estimated 45 percent of people are at risk of developing knee osteoarthritis (OA) in their lifetime. According to a network meta-analysis research article published in the May 1, 2018 issue of the Journal of the American Academy of Orthopaedic Surgeons, the nonsteroidal anti-inflammatory drug naproxen was ranked most effective in individual knee OA treatment for improving both pain and function, and is considered a relatively safe and low-cost treatment method.

2 May 2018