Acetaminophen News and Research

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The pain-reliever acetaminophen (also known as paracetomol) is one of the best-selling over-the-counter medications, used by more than 200 million Americans a year. It is sold under many brand names, including Tylenol, and is an ingredient in nearly 200 medications, both over-the-counter (such as Excedrin, Midol, NyQuil, and Sudafed) and prescription (such as Vicodin).

New pain management regimen reduced opioid exposure in trauma patients

A pain management regimen comprised mostly of over-the-counter medication reduced opioid exposure in trauma patients while achieving equal levels of pain control, according to a new study by physician-researchers at The University of Texas Health Science Center at Houston (UTHealth).

22 Jan 2021

Multimodal pain regimen minimizes opioid exposure, relieves acute pain in trauma patients

A multimodal pain regimen (MMPR) designed to minimize opioid exposure and relieve acute pain associated with traumatic injury kept patient self-reported pain scores low while also reducing the daily and total amount of opioid drugs given to trauma patients.

21 Jan 2021

Oral methotrexate can be an effective intervention for people with knee OA

A new study presented at ACR Convergence, the American College of Rheumatology's annual meeting, shows that after three months of treatment with oral methotrexate, adults with primary knee osteoarthritis (OA) with inflammation had significant improvements in physical function and inflammation, a sign that this inexpensive, generic pill may be an important intervention for knee OA.

6 Nov 2020

Researchers simplify and streamline guidelines for managing knee osteoarthritis

The burden of knee osteoarthritis is set to continue to increase around the world. Aging populations and rising levels of obesity, combined with an absence of a cure for the disease, will lead to an increased strain on health-care systems. Due to this, there is a focus on how to best manage the disease.

29 Oct 2020

Scientists uncover surprising players in acute liver failure

Acute liver failure is a devastating, rapidly progressing disease that results in death in 80% of cases, unless an emergency liver transplant is performed. In the developed world, its leading cause is a substantial overdose of acetaminophen, also known as paracetamol.

27 Oct 2020

New guidelines reduce number of opioid pills prescribed to patients after surgery

To address the opioid epidemic, surgeons have embraced guidelines to reduce the number of opioid pills they prescribe to patients after surgery, and the efforts have helped to significantly reduce the number of opioids in circulation.

5 Oct 2020

Using a pain reliever can increase risk-taking behavior

While acetaminophen is helping you deal with your headache, it may also be making you more willing to take risks, a new study suggests.

8 Sep 2020

Polygenic risk score can predict risk of drug-induced liver injury

Scientists who were working on a way to determine the viability of batches of tiny liver organoids have discovered a testing method that may have far broader implications.

7 Sep 2020

Other forms of treatments are as effective as opioids for acute musculoskeletal injuries

Two new evidence reviews related to acute musculoskeletal injuries like strains and sprains suggest other forms of treatments are as effective as opioids and have less risk of harms to patients.

18 Aug 2020

Novel strategy provides new hope to fight COVID-19

A novel strategy has been developed by Novateur Ventures, which provides new hope in battle against COVID-19. The study titled 'A Novel Strategy to Mitigate the Hyperinflammatory Response to COVID-19 by Targeting Leukotrienes' was published in Frontiers in Pharmacology, a leading peer-reviewed journal.

12 Aug 2020

Researchers identify new treatment for osteoarthritis

The study results revolve around the long-established idea that machines within animal and human cells turn the sugars, fats, and proteins we eat into energy used by the body's millions of cells.

10 Aug 2020

Custom smartwatch tracks drug levels inside the body in real time

Engineers at the UCLA Samueli School of Engineering and their colleagues at Stanford School of Medicine have demonstrated that drug levels inside the body can be tracked in real time using a custom smartwatch that analyzes the chemicals found in sweat.

7 Aug 2020

Study: Suicide-related OTC analgesics cases have increased dramatically among females and children

Over-the-counter (OTC) analgesics like acetaminophen, ibuprofen, and acetylsalicylic acid (aspirin) have long been a staple in households for managing pain, fevers, and other common ailments.

27 Jul 2020

Study shows inert drug ingredients could lead to unanticipated side effects

Some supposedly inert ingredients in common drugs -- such as dyes and preservatives -- may potentially be biologically active and could lead to unanticipated side effects, according to a preliminary new study by researchers from the UC San Francisco School of Pharmacy and the Novartis Institutes for BioMedical Research (NIBR).

24 Jul 2020

$Ibuprofen use does not affect fracture healing in children, study shows$

Ibuprofen use does not affect fracture healing in children, study shows

Doctors have traditionally avoided prescribing nonsteroidal anti-inflammatory medications (NSAIDs) such as ibuprofen to patients with fractures.

22 Jul 2020

Electro-oxidation process can revolutionize the field of wastewater treatment

Pesticides, pharmaceutical products, and endocrine disruptors are some of the emerging contaminants often found in treated domestic wastewater, even after secondary treatment.

9 Jul 2020

Researchers discover novel class of safer analgesics

Researchers at LSU Health New Orleans Neuroscience Center of Excellence and colleagues have discovered a new class of pipeline drugs to relieve pain and reduce fever without the danger of addiction or damage to the liver or kidneys.

6 Jul 2020

Study examines changes in prescription patterns during COVID-19 pandemic

A new study by investigators from Brigham and Women's Hospital examines changes in prescription patterns in the United States during the COVID-19 pandemic.

29 May 2020

Biomechanical footwear reduces pain associated with knee osteoarthritis

Wearing shoes specifically designed with a novel sole (biomechanical footwear) significantly reduces the pain associated with knee osteoarthritis.

12 May 2020

Analysis: We knew the coronavirus was coming, yet we failed 5 critical tests

The arrival of COVID-19 has provided a nuclear-level stress test to the American health care system, and our grade isn't pretty: at least 73,000 dead, 1.2 million infected and 30 million unemployed; nursing homes, prisons and meatpacking plants that have become hotbeds of infection.

11 May 2020