Acetaminophen News and Research

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The pain-reliever acetaminophen (also known as paracetomol) is one of the best-selling over-the-counter medications, used by more than 200 million Americans a year. It is sold under many brand names, including Tylenol, and is an ingredient in nearly 200 medications, both over-the-counter (such as Excedrin, Midol, NyQuil, and Sudafed) and prescription (such as Vicodin).

Unexpected function of enzyme in sounding alarm about liver damage could lead to new treatments

On a normal day, the cells of a human liver do what they do best - making key blood proteins, clearing toxins from the blood and sending their remains down the digestive tract in a never-ending stream of bile.

9 Apr 2019

Acetaminophen can limit positive empathy for others, study shows

A new study by an Ohio University faculty member showed that acetaminophen limited positive empathy a person has for others while taking it.

8 Apr 2019

Common pain reliever may increase stroke risk in people with diabetes

Acetaminophen (otherwise known by brand names such as Tylenol) is one of the most widely used pain relievers.

3 Apr 2019

Woman who does not feel pain

A woman has been identified by doctors to be able to withstand pain. Surgeons were surprised to encounter her when they noticed that she made a completely painless recovery after a surgery.

28 Mar 2019

Machine learning approach sheds light on the biology of liver and kidneys after toxin exposure

Exposure to potentially harmful chemicals is a reality of life. Our ancestors, faced with naturally occurring toxins, evolved mechanisms to detoxify and expel damaging substances.

15 Mar 2019

Liver tissue model can help investigate the effects of RNA interference

Novel therapies based on a process known as RNA interference hold great promise for treating a variety of diseases by blocking specific genes in a patient's cells. Many of the earliest RNAi treatments have focused on diseases of the liver, because RNA-carrying particles tend to accumulate in that organ.

6 Mar 2019

Study finds drug interactions in ER's are common but could be prevented

In a recent Rutgers study, 38 percent of patients discharged from the emergency department had at least one drug interaction resulting from a newly prescribed medicine.

26 Feb 2019

The American Heart Association issues new reference toolkit for healthcare providers

With nearly half of American adults having elevated blood pressure, it’s important for everyone to understand that some common habits may affect blood pressure, making the condition more difficult to control.

21 Feb 2019

Penn's novel ERAS protocol for spinal surgery patients reduces opioid use

A novel "Enhanced Recovery After Surgery" (ERAS) protocol developed by Penn Medicine for patients undergoing spinal and peripheral nerve surgery significantly reduced opioid use.

25 Jan 2019

Opioid drugs often overprescribed to children for pain relief, say CHOP surgeons

Opioid drugs prescribed to children for pain relief after a typical pediatric orthopaedic procedure may be significantly overprescribed, according to a new study by researchers at Children's Hospital of Philadelphia (CHOP).

17 Jan 2019

Researchers harness visible light to develop safer building block for drug discovery

When you reach for a bottle of acetaminophen, you may be looking for relief from a headache. But if you take more than what is recommended, the drug can damage your liver.

22 Nov 2018

Researchers develop powerful method to solve structures of small molecules

Small molecules -- from naturally occurring metabolites and hormones to synthetic medicines and pesticides -- can have big effects on living things. But for scientists to understand how the molecules work and how to design beneficial ones, they need to know the precise arrangement of atoms and chemical bonds.

9 Nov 2018

Intake of painkillers during pregnancy linked to early puberty in future offspring

The more weeks a women takes pain-reliving medication during pregnancy, the earlier their daughters enter puberty. This is shown by a new study from Aarhus University.

23 Oct 2018

Researchers uncover how common pain reliever causes liver failure

Acetaminophen is a common pain reliever found in every pharmacy. However, it is also the No. 1 cause of acute liver failure in the United States. In the liver, acetaminophen is converted into a new compound that covalently binds to proteins at an amino acid called cysteine.

11 Oct 2018

Low-dose aspirin use associated with reduced ovarian cancer risk

Taking a low-dose aspirin daily may help women lower their risk of developing ovarian cancer. A new study co-led by Moffitt Cancer Center found that women who reported taking a low-dose aspirin every day had a 23 percent lower risk of ovarian cancer compared to nonaspirin users.

4 Oct 2018

Phase 3 ECHELON-2 clinical trial evaluating ADCETRIS plus CHP meets primary endpoint

Seattle Genetics, Inc. and Takeda Pharmaceutical Company Limited announced today that the phase 3 ECHELON-2 clinical trial met its primary endpoint.

1 Oct 2018

Immunologist to study how Chikungunya causes devastating effects in older adults

Emerging viruses such as Ebola, SARS and swine flu are familiar sounding, yet seemingly distant diseases to many Americans. But that's not the case with Chikungunya, a mosquito-borne virus that recently struck close to home and has proven deadly for the elderly.

25 Sep 2018

ADCETRIS drug receives approval in Japan as frontline treatment option for Hodgkin lymphoma

Seattle Genetics, Inc. today announced that its collaborator, Takeda Pharmaceutical Company Limited, has received approval from the Japanese Ministry of Health, Labour and Welfare for ADCETRIS (brentuximab vedotin) in combination with doxorubicin, vinblastine and dacarbazine as a frontline treatment option for CD30-positive Hodgkin lymphoma patients in Japan.

24 Sep 2018

Christiana Care Health System successfully reduces opioid prescriptions

Before surgeon Emily Penman, M.D., begins a mastectomy or lumpectomy, her lightly sedated patient receives a nerve block, an injection of medicine to control pain after surgery.

21 Aug 2018

Tandem Diabetes Care introduces t:slim X2 Insulin Pump with Basal-IQ Technology in the US

Tandem Diabetes Care, Inc. , a medical device company and manufacturer of the only touchscreen insulin pumps with continuous glucose monitoring (CGM) integration, today announced its launch of the t:slim X2 Insulin Pump with Basal-IQ™ Technology, a predictive low glucose suspend (PLGS) feature designed to help reduce the frequency and duration of low glucose events (hypoglycemia).

17 Aug 2018