Acid Reflux News and Research

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Acid reflux disease is a condition that often results when a valve located at the end of the esophagus malfunctions. When this valve relaxes inappropriately, it may allow stomach acid to splash up and irritate the lining of the esophagus, creating the sensation called heartburn, and other uncomfortable symptoms. Frequent, persistent heartburn is the primary symptom associated with acid reflux disease or GERD.

Patent for Aciphex ruled valid and enforceable

PriCara, Division of Ortho-McNeil-Janssen Pharmaceuticals, Inc., announced today that the U.S. Federal Circuit Court of Appeals affirmed the judgments of the United States District Court for the Southern District of New York that the patent for Aciphex (rabeprazole sodium 20 mg tablets) is valid and enforceable.

21 Jul 2008

Radiofrequency ablation is an effective treatment for dysplasia in people with Barrett's esophagus

Interim results from a nationwide clinical trial led by a University of North Carolina at Chapel Hill researcher suggest that radiofrequency ablation is an effective treatment for dysplasia in people with Barrett's esophagus, a condition that can lead to deadly gastrointestinal cancer.

19 May 2008

FDA grants priority review for ACIPHEX (rabeprazole sodium) sNDA for treatment of GERD in adolescents

Eisai Corporation of North America, a wholly-owned subsidiary of Tokyo-based Eisai Co., Ltd., has announced that the Food and Drug Administration (FDA) has accepted an ACIPHEX supplemental New Drug Application (sNDA) for the short-term (up to eight weeks) treatment of gastroesophageal reflux disease (GERD) in patients ages 12-16.

3 Mar 2008

Merck to pay over $650 million for fraudulent price reporting and kickbacks claims

Merck & Company has agreed to pay more than $650 million to resolve allegations that the pharmaceutical manufacturer failed to pay proper rebates to Medicaid and other government health care programs and paid illegal remuneration to health care providers to induce them to prescribe the company's products, the Justice Department has announced.

8 Feb 2008

Heartburn during pregnancy

Heartburn symptoms are one of the most commonly reported complaints among pregnant women.

10 Dec 2007

Incisionless surgery for acid reflux disease

Surgeons at the Ohio State University Medical Center have performed the first incisionless operations in the United States using a device recently approved by the Food and Drug Administration to stop gastroesophageal reflux disease.

24 Oct 2007

Children who are obese or who are at risk for obesity show early signs of heart disease

Childhood obesity in the United States is an epidemic -- nationwide, 19 percent of children ages 6 to 11 and 17 percent of those 12 to 19 are overweight, according to the Centers for Disease Control and Prevention (CDC). Those who are overweight during childhood also have an increased risk of obesity in adulthood and are at greater risk for complications such as diabetes, high blood pressure and heart disease, because obesity increases total blood volume, which leads to extra stress on the heart.

18 Oct 2007

Nighttime acid reflux and sleep

According to results of a survey presented at the 72nd Annual Scientific Meeting of the American College of Gastroenterology, nighttime acid reflux, along with some of the less typical manifestations or symptoms of gastroesophageal reflux disease (GERD), is associated with significant sleep impairment.

16 Oct 2007

Night-time acid reflux can impact sleep

16 Oct 2007

GERD can masquerade as persistent cough or even severe chest pain

Many people may not realize that symptoms such as chronic cough or chest pain can be caused by acid reflux into the esophagus, because they do not experience classic heartburn symptoms or acid regurgitation.

16 Oct 2007

Obese people six times more likely to develop oesophageal cancer

Rates of oesophageal cancer have been rising rapidly, and in some countries, they have risen faster than those of every other major cancer, say the authors.

10 Oct 2007

Married esophageal cancer patients fare worse in some quality of life aspects than single patients

In a surprising finding, American scientists have found that when battling oesophageal cancer, married patients don't fare as well as their single counterparts in certain aspects of their quality of life.

27 Sep 2007

New clues to why persistent acid reflux can turn into cancer

New research from scientists at UT Southwestern Medical Center and the Dallas Veterans Affairs Medical Center underscores the importance of preventing recurring acid reflux while also uncovering tantalizing clues on how typical acid reflux can turn potentially cancerous.

13 Aug 2007