Acromegaly News and Research

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Acromegaly is a syndrome that results when the pituitary gland produces excess growth hormone (hGH) after epiphyseal plate closure at puberty.

Gleevec receives FDA priority review for gastrointestinal stromal tumors after surgery

Novartis has announced that Gleevec (imatinib mesylate) tablets, (known as Glivec (imatinib) outside the US, Canada and Israel), has been granted priority review status by the US Food and Drug Administration (FDA) as the first therapy to be reviewed for use after surgery in kit-positive gastrointestinal stromal tumors (GIST).

27 Aug 2008

Human growth hormone abuse raises serious health risks

Human growth hormone (HGH), when medically necessary, is a safe and effective clinical treatment for children and adults.

13 Feb 2008

FDA approves Somatuline Depot to treat acromegaly

The U.S. Food and Drug Administration has approved Somatuline Depot (lanreotide acetate injection) for the treatment of acromegaly, a rare and potentially life threatening disease in adults caused by abnormal secretion of growth hormone (GH), commonly from a benign tumor located in the pituitary gland located in the brain.

30 Aug 2007

Pituitary adenoma predisposition caused by germline mutations in the AIP gene

A recent Finnish study identifies a low-penetrance gene defect which predisposes carriers to intracranial tumors called pituitary adenomas. In particular individuals carrying the gene defect are susceptible to such tumors which secrete growth hormone.

1 Jun 2006

Research explains why recipients of growth hormone therapy may develop colon polyps

The use of growth hormone therapy has been linked in some people to the development of colon polyps, a possible precursor to colorectal cancer - but medical researchers have debated the extent of a cancer risk.

11 Apr 2006

Protein loss linked to colon polyp risk from growth hormone

10 Apr 2006

New guidelines today to diagnose and treat acromegaly

The American Association of Clinical Endocrinologists (AACE) released new guidelines today to diagnose and treat acromegaly, a rare and debilitating endocrine disorder. The guidelines are published in the May/June 2004 issue of AACE's peer-reviewed journal Endocrine Practice.

29 Aug 2004

Two more drugs added to Medicare demonstration program

The Centers for Medicare & Medicaid Services has announced it is adding two more drugs to the list of drugs covered under a Medicare demonstration program providing substantial savings to beneficiaries with serious diseases, including cancer, multiple sclerosis, and rheumatoid arthritis.

17 Aug 2004