Acute Lymphoblastic Leukemia News and Research

RSS

Acute lymphoblastic leukemia (ALL) is a cancer of the white blood cells, the cells in the body that normally fight infections. There are two main types of white blood cells-lymphoid cells and myeloid cells. ALL affects lymphoid cells.

Research reviews role of protein tyrosine phosphatase in molecular biology

As the proteomics technology develops and human genomic analysis becomes easier to execute, molecules involved in the regulation of biochemical signaling pathways have become interesting subjects for researchers.

28 Dec 2018

CHLA researcher reveals how leukemia burrows within the bone marrow

Actually, cancer can hide. A researcher at Children's Hospital Los Angeles tells us exactly how leukemia burrows within bone marrow, where it is shielded from chemotherapy treatments.

21 Dec 2018

Genetic marker, predictor of early relapse in common childhood cancer discovered

Nova Southeastern University researchers recently discovered that by testing the level of NER (nucleotide excision repair) gene expression, pediatric oncologists can determine the likelihood of early relapse (less than three years) in their acute lymphoblastic leukemia patients.

14 Dec 2018

Physician-scientists present updated efficacy data on CAR T-cell gene immunotherapy

Physician-scientists from Children's Hospital of Philadelphia presented updated efficacy and safety data on Kymriah--the first-ever U.S. Food and Drug Administration approved personalized CAR T-cell gene immunotherapy for aggressive blood cancers at the 60th American Society of Hematology annual meeting, as well as first-of-its-kind research on overcoming CAR T-cell resistance.

5 Dec 2018

New strategies may improve performance of CAR-T cell therapy in treating cancer

Mayo Clinic researchers have developed two new strategies that may improve the performance of chimeric antigen receptor therapy in treating cancer. They are presenting results of their preclinical research at the 2018 annual meeting of the American Society of Hematology in San Diego.

3 Dec 2018

Research highlights ability of Bio-Rad's ddPCR in quantifying minimal residual disease

More than 30 abstracts presented at the 60th American Society of Hematology Annual Meeting & Exposition in San Diego, December 1-4, featured research highlighting the ability of Bio-Rad's Droplet Digital PCR to provide high sensitivity and accuracy in quantifying minimal residual disease -- those remaining cancer cells after therapy that are associated with relapse -- in blood diseases such as leukemia.

3 Dec 2018

SSB enters into collaboration with Immunochina to develop new immunotherapy equipment

Sartorius Stedim Biotech, a leading international supplier of the biopharmaceutical industry, through its China affiliate, and Beijing-based Immunochina Pharmaceuticals, announced today that both parties have entered into a collaboration.

3 Dec 2018

CAR T therapy can lead to long-lasting remissions in patients with r/r diffuse large B-cell lymphoma

In an update to a global clinical trial stretching from Philadelphia to four continents, the chimeric antigen receptor (CAR) T cell therapy Kymriah (tisagenlecleucel, formerly CTL019) led to long-lasting remissions in patients with relapsed/refractory (r/r) diffuse large B-cell lymphoma (DLBCL).

3 Dec 2018

Triple combination cancer immunotherapy improves survival in mouse model of melanoma

Adoptive cell transfer is a promising cancer immunotherapy that involves isolating T cells from cancer patients that are capable of targeting their tumor, selecting the more active T cells and expanding those in the lab, and then transfusing them back into patients.

30 Nov 2018

Abramson Cancer Center becomes the 28th member institution of National Comprehensive Cancer Network

The Abramson Cancer Center (ACC) at the University of Pennsylvania announced today that it is joining the National Comprehensive Cancer Network (NCCN) as its 28th member institution.

20 Nov 2018

St. Jude Hospital announces availability of largest collections of leukemia samples

St. Jude Children's Research Hospital today announced the availability of one of the world's largest collections of leukemia samples from children and adults.

15 Nov 2018

Amgen announces presentation of new clinical data showcasing early oncology pipeline at ASH 2018

Amgen today announced that new clinical data will be presented at the 60th American Society of Hematology Annual Meeting & Exposition in San Diego, Dec. 1-4, 2018. Data across an array of malignancies will be featured in 45 abstracts, including nine oral presentations, from the Company’s broad portfolio andearly-stage pipeline.

From AMGEN 5 Nov 2018

Why patients with ALL relapse after CAR-T cell therapy

Researchers have made a new discovery about a rare mechanism that triggers the relapse of acute lymphoblastic leukemia (ALL) after CAR T cell therapy.

1 Oct 2018

Why patients with ALL relapse after CAR-T cell therapy

Researchers have made a new discovery about a rare mechanism that triggers the relapse of acute lymphoblastic leukemia (ALL) after CAR T cell therapy.

1 Oct 2018

New analysis confirms value of minimal residual disease as prognostic indicator in multiple myeloma

Adaptive Biotechnologies today announced that Blood, the Journal of the American Society of Hematology, published online an analysis of patient samples from the Intergroupe Francophone du Myéloma 2009 trial.

1 Oct 2018

FDA permits marketing of ClonoSEQ assay to detect minimal residual disease in blood cancer patients

Today the U.S. Food and Drug Administration permitted marketing of ClonoSEQ assay, a next generation sequencing-based test for minimal residual disease in patients with acute lymphoblastic leukemiaor multiple myeloma. MRD is a measure of the amount of cancer cells remaining in a person's bone marrow.

30 Sep 2018

Lower clinical trial enrollment associated with relapse risk in AYA leukemia patients

Adolescent and young adult patients with acute lymphoblastic leukemia were significantly more likely to relapse than pediatric ALL patients, and factors including lower clinical trial enrollment and shorter duration of therapy were associated with relapse.

27 Sep 2018

Acute Lymphoblastic Leukemia News and Research

Further Reading

Research reviews role of protein tyrosine phosphatase in molecular biology

CHLA researcher reveals how leukemia burrows within the bone marrow

Genetic marker, predictor of early relapse in common childhood cancer discovered

Physician-scientists present updated efficacy data on CAR T-cell gene immunotherapy

New strategies may improve performance of CAR-T cell therapy in treating cancer

Research highlights ability of Bio-Rad's ddPCR in quantifying minimal residual disease

SSB enters into collaboration with Immunochina to develop new immunotherapy equipment

CAR T therapy can lead to long-lasting remissions in patients with r/r diffuse large B-cell lymphoma

Triple combination cancer immunotherapy improves survival in mouse model of melanoma

Abramson Cancer Center becomes the 28th member institution of National Comprehensive Cancer Network

St. Jude Hospital announces availability of largest collections of leukemia samples

Amgen announces presentation of new clinical data showcasing early oncology pipeline at ASH 2018

Why patients with ALL relapse after CAR-T cell therapy

Why patients with ALL relapse after CAR-T cell therapy

New analysis confirms value of minimal residual disease as prognostic indicator in multiple myeloma

FDA permits marketing of ClonoSEQ assay to detect minimal residual disease in blood cancer patients

Lower clinical trial enrollment associated with relapse risk in AYA leukemia patients

Study: Children with acute lymphoblastic leukemia are immunologically disparate at birth

New system accelerates discovery of chemical compounds that inhibit enzyme implicated in cancers

Research shows new way to target drug delivery for brain tumors

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Latest News