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New passive vaccine reverses dangerous symptoms of cocaine overdose

Scientists are reporting development and successful testing in laboratory mice of a substance that shows promise for becoming the first antidote for cocaine toxicity in humans. According to a report in ACS' journal Molecular Pharmaceutics, the new so-called "passive vaccine" reversed the motor impairment, seizures and other dangerous symptoms of a cocaine overdose, which claims thousands of lives each year among users of the illicit drug.

19 Apr 2012

First specific antidote for cocaine toxicity

Scientists at The Scripps Research Institute have shown that an injectable solution can protect mice from an otherwise lethal overdose of cocaine. The findings could lead to human clinical trials of a treatment designed to reverse the effects of cocaine in case of emergency. Cocaine is involved in more than 400,000 emergency-room visits and about 5,000 overdose deaths each year in the United States.

19 Apr 2012

Half of young adult tobacco smokers also have used marijuana in the last 30 days

Half of young adult tobacco smokers also have smoked marijuana in the last 30 days, according to a recent Facebook-based survey conducted by UCSF researchers, indicating a greater prevalence of marijuana and tobacco co-use among smokers age 18-25 than previously reported.

19 Apr 2012

Addiction to opioids has higher risk of death than alcohol or other drugs

People with an opioid addiction had the highest risk of death when compared with rates for alcohol and other drugs, according to a new study by the Centre for Addiction and Mental Health (CAMH).

18 Apr 2012

New study describes therapeutic approach to halt cancer progression

A new study describes a therapeutic approach to halting cancer progression by exploiting a previously unrecognized "addiction" of leukemia cells to specific signaling molecules. The research, published by Cell Press online on April 16th in the journal Cancer Cell, identifies non-classical oncogenes critical for tumor development and survival, and describes a potentially less toxic strategy that selectively targets these molecules.

17 Apr 2012

More than one third of patients with invasive cancer are undertreated for their pain

More than one third of patients with invasive cancer are undertreated for their pain, with minorities twice as likely to not receive analgesics, according to research from The University of Texas MD Anderson Cancer Center.

17 Apr 2012

Lung cancer rates continue to rise among UK women

Lung cancer cases continue to rise in women with more than 18,000 UK women diagnosed with the disease in 2009 according to the latest Cancer Research UK figures released today.

16 Apr 2012

Med-Tek introduces proprietary Opioid Management Program

Med-Tek a developer of Healthcare Technology Networks ("HTN") designed to improve outcomes for patients, physicians, employers and their constituents today announces the launch of its proprietary Opioid Management Program (OMP).

9 Apr 2012

Viewpoints: An 'easy' SCOTUS case?; Is painkiller addiction really an epidemic?

Nothing in the Supreme Court arguments in the health care case last week, or in the subsequent commentary, has changed my opinion that this is an easy case. It's the court that made it look hard (Linda Greenhouse, 4/4).

7 Apr 2012

AP: Prescription painkiller sales have 'exploded,' leading experts to fear 'addiction epidemic'

Sales of the nation's two most popular prescription painkillers have exploded in new parts of the country, an Associated Press analysis shows, worrying experts who say the push to relieve patients' suffering is spawning an addiction epidemic.

6 Apr 2012

Purdue Pharma launches Intermezzo for middle-of-the-night insomnia

Purdue Pharma L.P. announced today that Intermezzo (zolpidem tartrate) sublingual tablet CIV is now available in 1.75 mg and 3.5 mg dosage strengths by prescription in retail pharmacies nationwide.

6 Apr 2012

Some smokers quit smoking on first try while others have to quit repeatedly

Some people quit smoking on the first try while others have to quit repeatedly. Using such mobile technology as hand-held computers and smartphones, a team of researchers from Penn State and the University of Pittsburgh is trying to find out why.

5 Apr 2012

First Edition: April 5, 2012

In today's headlines, reports about how the budget debate is mixing into presidential poiltics.

5 Apr 2012

NIDA to showcase PEERx teen initiative at National RX Drug Abuse Summit

A unique, new campaign targeting teens will be on exhibit at the first national summit addressing the prescription drug abuse epidemic. The National Institute on Drug Abuse (NIDA) will showcase "PEERx," a NIDA initiative that uses interactive videos and other tools to educate teens about the dangers of prescription drug abuse and help them to spread the word.

4 Apr 2012

Brains of people with anorexia and obesity are wired differently

The brains of people with anorexia and obesity are wired differently, according to new research. Neuroscientists for the first time have found that how our brains respond to food differs across a spectrum of eating behaviors - from extreme overeating to food deprivation.

4 Apr 2012

NIDA awards $1.4M grant to aid development of formal addiction medicine training programs

Boston Medical Center physician Jeffrey Samet, MD, chief, section of general internal medicine, in collaboration with Co-Principal Investigator, Patrick O'Connor, MD, chief section of general internal medicine at Yale School of Medicine, were awarded a five-year, $1.4 million grant from the National Institute On Drug Abuse to aid the development of formal addiction medicine training programs.

3 Apr 2012

TLR4/MD-2 protein complex triggers morphine-induced inflammation

A University of Colorado Boulder-led research team has discovered that two protein receptors in the central nervous system team up to respond to morphine and cause unwanted neuroinflammation, a finding with implications for improving the efficacy of the widely used painkiller while decreasing its abuse potential.

3 Apr 2012

Health reform means ER use jumps in Colo.; Calif. insurance premiums rise; Ore. waits to see who wants in on coordinated care

Even people who just got health insurance use the emergency departments to access their care, according to a new study by University of Colorado School of Medicine researchers. It's not just people who lost insurance or people living long without it, the researchers note -- any change in health insurance status, whether positive or negative, tends to send people to the ER because they don't know where else to go.

3 Apr 2012

Nektar commences dosing in NKTR-192 Phase 1 clinical study for treatment of acute pain

Nektar Therapeutics announced today that the first subjects were dosed last week in a Phase 1 clinical study to evaluate the pharmacokinetics and safety of NKTR-192, the company's novel short-acting mu-opioid analgesic candidate.

2 Apr 2012

FDA releases two draft guidance documents to help fight tobacco epidemic

Today the U.S. Food and Drug Administration (FDA) released two separate draft guidance documents to help fight the tobacco epidemic and stop children from using tobacco. The draft guidance documents implement provisions of the Family Smoking Prevention and Tobacco Control Act that will ultimately provide the public with previously unknown information about the chemicals in tobacco products and help prevent misleading marketing about the risks associated with tobacco products.

31 Mar 2012